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祁争健

领域:新材料产业 学校:东南大学职称:教授

荧光探针和生物成像:

基于萘酰亚胺、异氟尔酮、呫吨和罗丹明B等荧光团对生物体内中P450蛋白酶、半胱氨酸、谷胱甘肽和金属离子等的特异性识别和生物活体成像。




Talanta, 2018, 186, 413-420

Sensors and Actuators B-Chemical, 2019, 293,265-272


Journal of Luminescence, 2019, 207, 613-619


Spectrochimica Acta Part A: Molecular andBiomolecular Spectroscopy, 2019, 216, 365-374
有机(聚合物)电致发光材料及器件:
OLED:


PLED:


有机硅功能材料:                          
"Click reaction"构建有机硅功能材料及其在生物、医药和环境保护等领域的应用。


                                       

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具体了解该专家信息,请致电:027-87555799 邮箱 haizhi@uipplus.com

教育背景

工作经历

项目课题经历

论文、成果、著作等

已主持完成国家自然科学基金、国家科技支撑子项、江苏省科技支撑、江苏省技术储备、江苏省中青年科技骨干培养、南京市重大专利转化和企业委托等项目多项,参与并完成国家“七五”、“八五”科技攻关课题和江苏省自然科学基金等项目。目前主持或参与在研江苏省科技成果转化项目、国家重大科学仪器设备开发专项和企业委托项目等多项。已发表SCIEI等研究论文40余篇,申请国家发明专利12件,获授权7件。


代表作及发明专利

1.  F. Ma, Y. Cheng, Y. Zheng, H. Ji, K. Hasrat, Z. Qi, Rational design of thermally activated delayed fluorescence emitters with aggregation-induced emission employing combined charge transfer pathways for fabricating efficient non-doped OLEDs, Journal of Materials Chemistry C, 7 (2019) 9413-9422.

2. Xue, TZ, Dai, YP, Zhang, XX,Cheng, Y, Gu, XF, Ji, HF, Misal, S, Qi, ZJ*, Ultrasensitive nearinfrared fluorescent probe with large stokes shift for real-time tracing of CYP1A1 inliving cells and zebrafish model. Sensors and Actuators B-Chemical, 2019, 293,265-272.

3. H. Ji, X. Zhang, Y. Dai, T. Xue, S. Misal, Z. Qi, A highly selective ratiometric fluorescent probe based on naphthalimide for detection and imaging of CYP1A1 in living cells and zebrafish, Analyst, 2019, DOI: 10.1016/j.saa.2019.117490.

4. Ma FL, Cheng, Y, Zhang, XX, Gu,XF, Zheng, Y, Hasrat, K, Qi, ZJ*, Enhancing performance for blue TADF emittersby introducing intramolecular CH center dot center dot center dot N hydrogenbonding between donor and acceptor. Dyes and Pigments, 2019, 166, 245-253.

5. X. Zhao, F. He, Y. Dai, F. Ma, Z. Qi, A single fluorescent probe for one- and two-photon imaging hydrogen sulfide and hydrogen polysulfides with different fluorescence signals, Dyes and Pigments, 2020, DOI: 10.1016/j.dyepig.2019.107818.

6. Y. Dai, Y. Zheng, T. Xue, F. He, H. Ji, Z. Qi, A novel fluorescent probe for rapidly detection cysteine in cystinuria urine, living cancer/normal cells and BALB/c nude mice, Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 225 (2019) 117490-117490.

7. Dai YP, Xue TZ, Zhang XX, MissaS, Ji HF, Qi ZJ*, A novel probe for colorimetric and nearinfrared fluorescencedetection of cysteine in aqueous solution, cells and zebrafish. SpectrochimicaActa Part A: Molecular and Biomolecular Spectroscopy, 2019, 216, 365-374.

8. Zhang XX, Zhou Y, Gu XF, Cheng Y,Hong MX, Yan LQ, Ma FL, Qi ZJ*, Synthesis of a selective ratiometricfluorescent probe based on Naphthalimideand its application in human cytochromeP450 1A. Talanta, 2018, 186, 413-420.

9. Gu XF, Zhang XX, Liu Z, Cheng, Y, MaFL, Dai YP, Xue TZ, Zheng Y, Qi ZJ*, Anovel near-infrared "turn on" fluorescent probe for selective detection of Fe3+ and its application in vitro imaging. Journal of Luminescence,2018, 207, 613-615.

10. Cheng Y, Ma FL, Gu XF, Liu Z,Zhang XX, Xue TZ, Zheng Y, Qi ZJ*, A novel isophorone-based red-emitting/ NIR  probe for thiophenol  and  its  application  in real water sample and vivo.Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2019, 210,281-288.

11.Yan LQ, Li RJ, Shen W, Qi ZJ*, Multiple–color AIEcoumarin based Schiff  bases and potential  application  inyellow  OLEDs.  Journal of  Luminescence,  2018, 19,151-155.

12. Li RJ, Yan LQ, Wang ZW, Qi ZJ*,Anaggregationinducedemissive NIR luminescent based on ESIPT and TICTmechanismsandits application to the detection of Cys. Journal of MolecularStructure, 2017,1136,1-6.

13. Liqiang Yan, Renjie Li, Fulong Maand Zhengjian Qi*, A simple salicylaldehydebased fluorescent “turn on”probefor  selective detection of  Zn2+  in water solution and its application in live cell imaging. Analytical Methods, 2017, 9, 1119-1124.

14. Li Qiang Yan, Zhi Neng Kong, YongXia and Zhengjian Qi*, Anovel coumarin-based red fluorogen with AIE, selfassembly, and TADF  properties.  New Journal of Chemistry, 2016, 40,7061-7067.

15. Liqiang Yan, Zhineng Kong, WeiShen, Wenqi Du, Yan Zhou and Zhengjian Qi*, An aggregationinduced emission(AIE) ratiometric      fluorescent cysteine probe with an exceptionally large blueshift.  RSC Advances, 2016, 6, 5636-5640.

16. Liqiang Yan, Tingting Qing, RenjieLi, Zhongwei Wang and Zhengjian Qi*, Synthesis and optical properties ofaggregationinduced emission(AIE) molecules based on the ESIPT mechanism as pHand Zn2+ responsivefluorescent sensors. RSC Advances, 2016, 6, 63874-63879.

17. Liqiang Yan, Yan Zhou, Wenqi Du,Zhineng Kong, Zhengjian Qi*, A new turn on coumarinbased fluorescence probefor Ga3+ detection in aqueous solution. SpectrochimicaActa Part A: Molecularand Biomolecular Spectroscopy, 2016,155, 116-124.

18. Renjie Li, Liqiang Yan, ZhongweiWang, Zhengjian Qi*, Anaggregationinduced emissive NIR luminescent based onESIPT and TICT mechanismsand its application to the detection of Cys. Journalof Molecular Structure, 2017,1136, 1-6.

19. Zhineng Kong, Wenting Wu, JingYan, Baoying Wu, Yan Zhou, Wenqi Du, Zhengjian Qi*, A simple, efficient andmetalfree route to amphiphilictriblock copolymers containing PDMS and PEGsegments: synthesis, characterizationand selfassembly in aqueous media.Journal of Polymer Research, 2016, 23:245.

20. 祁争健,王中伟,李仁杰,马夫龙,一种pH响应型维生素E载药材料及其制备方法和应用, CN108329463A

21. 祁争健,陈会敏,闫力强,复合改性环氧树脂结构胶及复合改性剂和结构胶制备方法,CN108048007A

22. 祁争健,吴保嬴,孔志能,杜文琦,周妍,一种聚硅氧烷弹性体及其巯基#烯点击反应制备方法,CN106478956A

23. 祁争健,杨帆,崔美芳,一种超灵敏氧传感器及其制备方法,CN103969238B

24. 祁争健,孙岳明,洪满心,噻吩--噁二唑作为氧猝灭物质的应用,CN102516836B

25. 祁争健,洪满心,孙岳明,PPV类聚合物作为荧光指示剂在基于荧光猝灭的氧传感器中的应用,CN102516990B

26. 祁争健,罗振扬,异佛尔酮二异氰酸酯三聚体复合物的制备方法,CN1283631C

27. 祁争健,孙岳明,冯卫东,一种3-辛基噻吩-共聚-3-(2-乙基-1-己基)噻吩的制备方法,CN100487017C

28. 祁争健,韦斌,孙岳明,一种主链含双键的噻吩交替共聚物及制备方法,CN101328256B

29. 祁争健,1,2,-(3,3,4,4-四甲基二苯)乙烷的生产方法,CN1046698C


学术交流:

1. Qi Zhengjian. Small Organic Molecule Fluorescence Probe and Its Application of Rapid Detection of Trace Metal Ions, The Extractables and Leachables, 2019, Shanghai, China. (邀请报告)

2.Qi Zhengjian. Fluorescence Chemosensor & Amphiphilic Copolyme, UNIVERSITY OF CALIFORNIA, RIVERSIDE, 2015.7, America. (邀请报告)

3.Qi Zhengjian. Natural Drug-loaded material and its application in electronic mask, 9th International Conference on Flexible and Printed Electronics, 2018, Changzhou, China. (邀请报告)

4.康凤,祁争健*.HPLC法在固载型微球催化剂制备草甘膦中的应用2010.5 无锡第四届华东地区色谱、质谱学术报告会(优秀论文奖)

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