教育背景
2006-2010 河南大学,应用化学,学士
2010-2012 上海交通大学,有机化学,硕士(导师:张万斌教授)
2013-2013 Tohoku University,有机化学,Campus Asia Program(联合导师:Prof. Masahiro Terada)
2012-2017 上海交通大学,药学,博士(导师:张万斌教授 刘燕刚教授)
工作经历
2017-2019 上海交通大学,博士后(合作导师:张万斌教授)
2019-至今 上海交通大学化学化工学院,特别研究员
项目课题经历
主持上海市“科技创新行动计划”青年科技英才扬帆计划、2018年中国博士后科学基金面上项目一等资助,并参与国家自然科学基金重点、重点国际合作和面上项目、上海市科委和教委重大和重点科技攻关项目等多项课题研究。
论文、成果、著作等
(1)X. Huo, J. Zhang, J. Fu, R. He, W. Zhang*. Ir/Cu Dual Catalysis: Enantio- and Diastereodivergent Access to α,α-Disubstituted α-Amino Acids Bearing Vicinal Stereocenters, J. Am. Chem. Soc. 2018, 140, 2080-2084.
(2)X. Huo,† J. Fu,† X. He, J. Chen, F. Xie, W. Zhang*. Pd/Cu Dual Catalysis: Highly Enantioselective Access to α-Substituted α-Amino Acids and α-Amino Amides, Chem. Comm. 2018, 54, 599-602. (†co-first author)
(3)X. Huo, R. He, J. Fu, J. Zhang, G. Yang, W. Zhang*. Stereoselective and Site-Specific Allylic Alkylation of Amino Acids and Small Peptides via a Pd/Cu Dual Catalysis, J. Am. Chem. Soc. 2017, 139, 9819-9822. (ESI Highly Cited Paper)
(4)X. Huo,† R. He,† X. Zhang, W. Zhang*. An Ir/Zn Dual Catalysis for Enantio- and Diastereodivergent α-Allylation of α-Hydroxyketones, J. Am. Chem. Soc. 2016, 138, 11093-11096. (ESI Highly Cited Paper) (†co-first author)
(5)X. Huo, G. Yang, D. Liu, Y. Liu, I. Gridnev*, Wanbin Zhang*. Palladium-Catalyzed Allylic Alkylation of Simple Ketones with Allylic Alcohols and Its Mechanistic Study, Angew. Chem. Int. Ed. 2014, 53, 6776-6780.
(6)X. Huo, M. Quan, G. Yang, X. Zhao, D. Liu*, Y. Liu, W. Zhang*. Hydrogen-Bond-Activated Palladium-Catalyzed Allylic Alkylation via Allylic Alkyl Ethers: Challenging Leaving Groups, Org. Lett. 2014, 16, 1570-1573.
(7)P. Liu,† X. Huo,† B. Li, R. He, F. Xie, W. Zhang*. Stereoselective Allylic Alkylation of 1-Pyrroline-5-carboxylic Esters via a Pd/Cu Dual Catalysis, Org. Lett. 2018, 20, 6564-6568. (†co-first author)
(8)J. Zhang,† X. Huo,† B. Li, Y. Zou, Z. Sun, W. Zhang*. Enantioselective and Diastereodivergent Access to α-Substituted α-Amino Acids via Dual Iridium and Copper Catalysis, Adv. Synth. Catal. 2019, 361, 1130-1139. (†co-first author)
专利、著作版权等
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