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苏畅

领域:生物产业 学校:武汉大学职称:副研究员

真菌致病性...

具体了解该专家信息,请致电:027-87555799 邮箱 haizhi@uipplus.com

教育背景

2003-2009 中科院上海生命科学研究院生物化学与细胞生物学研究所,博士
1999-2003 南开大学生物科学专业,学士

工作经历

2016-至今 武汉大学生命科学学院,副研究员
2015-2016 加州大学欧文分校医学院,研究助理
2010-2015 加州大学欧文分校医学院,博士后

项目课题经历

论文、成果、著作等

1. Chang Su*, Yang Lu*, and Haoping Liu. (2016) N-acetylglucosamine sensing by a GCN5-related N-acetyltransferase induces transcription via chromatin histone acetylation in fungi,Nature Communications,2016.10.03,7 (* equal contribution)

2. Yang Lu, Chang Su, and Haoping Liu. (2014) Candida albicans hyphal initiation and elongation. Trends in Microbiology 22(12): 707-14.

3. Yang Lu*, Chang Su*, Ohimai Unoje, and Haoping Liu. (2014) Quorum sensing controls hyphal initiation in Candida albicans through Ubr1-mediated protein degradation. PNAS 111(5): 1975-80. (* equal contribution)

4. Yang Lu, Chang Su, Norma V. Solis, Scott G. Filler, and Haoping Liu. (2013) Synergistic regulation of hyphal elongation by hypoxia, CO2, and nutrient conditions controls the virulence of Candida albicans. Cell Host & Microbe 14(5): 499-509.

5. Chang Su*, Yang Lu*, and Haoping Liu. (2013) Reduced TOR signaling sustains hyphal development in Candida albicans by lowering Hog1 basal activity. Molecular Biology of the Cell 24(3): 385-97. (* equal contribution)

6. Yang Lu, Chang Su, and Haoping Liu. (2012) A GATA transcription factor recruits Hda1 in response to reduced Tor1 signaling to establish a hyphal chromatin state in Candida albicans. PLoS Pathogens 8(4): e1002663.

7. Yang Lu, Chang Su, Allen Wang, and Haoping Liu. (2011) Hyphal development in Candida albicans requires two temporally linked changes in promoter chromatin for initiation and maintenance. PLoS Biology 9(7): e1001105.

8. Chang Su, Yandong Li, Yang Lu, and Jiangye Chen. (2009) Mss11, a transcriptional activator, is required for hyphal development in Candida albicans. Eukaryotic Cell 8(11):1780-91.

9. Yang Lu, Chang Su, Xuming Mao, Prashna Pala Raniga, Haoping Liu, and Jiangye Chen. (2008) Efg1-mediated recruitment of NuA4 to promoters is required for hypha-specific Swi/Snf binding and activation in Candida albicans. Molecular Biology of the Cell 19(10): 4260-72.

10. Yandong Li, Chang Su, Xuming Mao, Fang Cao, and Jiangye Chen. (2007) Roles of Candida albicans Sfl1 in hyphal development. Eukaryotic Cell 6(11): 2112-21.

专利、著作版权等

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