先后获得武汉大学微生物学专业学士和硕士学位后于1988年留校任教；1997年晋升为副教授；2002年在职获得博士学位；2004年晋升为教授 ，2005年遴选为博士生导师；曾赴美国、日本的多所高校交流访问；

先后主持国家自然科学基金项目8项，973子课题1项，多项国家自然科学基金，省、部级重点项目的主要参加者；承担多项横向研究课题；

1. Yunqian Qiao, Jiao Wang, He Wang, Baozhong Chai, Chufeng Rao, Xiangdong Chen*, Shishen Du*(2019),,4-hydroxyphenylpyruvate dioxygenase thermolability is responsible for temperature-dependent melanogenesis in Aeromonas salmonicida subsp. salmonicida, Appl. Environ, Microbiol. 85(1), e01926-18

2. Xiaoming Zhang, Tingting Jin, Liping Deng, Chao Wang, Yuhua Zhang, Xiangdong Chen* (2018), Stress-Induced, Highly Efficient, Donor Cell-Dependent Cell-toCell Natural Transformation in Bacillus subtilis, J Bacteriol 200(17): e00267-18.

3. Ruili Zhao, Rui Zhao, Yishuai Tu, Xiaoming Zhang, Liping Deng, Xiangdong Chen* (2018) A novel α-galactosidase from the thermophilic probiotic Bacillus coagulans with remarkable protease-resistance and high hydrolytic activity. PLoS ONE 13(5): 1-16,e0197067

4. Jiao Wang, Yingchun Liu, Ying Liu, Kaixin Du, Shuqi Xu, Yuchen Wang, Mart Krupovic, Xiangdong Chen* (2018) A novel family of tyrosine integrases encoded by the temperate pleolipovirus SNJ2, Nucleic Acids Res, 46(5):2521–2536, https://doi.org/10.1093/nar/gky005

5. Yuchen Wang, Beibei Chen, Mengzhuo Cao, Linshan Sima, David Prangishvili, Xiangdong Chen*, Mart Krupovic* (2018) Rolling-circle replication initiation protein of haloarchaeal sphaerolipovirus SNJ1 is homologous to bacterial transposases of the IS91 family insertion sequences, J Gen., Virol, 99: 416-421, doi: 10.1099/jgv.0.001009

6. Yuchen Wang, Beibei Chen, Linshan Sima, Mengzhuo Cao, and Xiangdong Chen* (2017) Construction of Expression Shuttle Vectors for the Haloarchaeon Natrinema sp. J7 Based on Its Chromosomal Origins of Replication，Archaea，Volume 2017, Article ID 4237079, 11 pages

7. Baozhong Chai, Yunqian Qiao, He Wang, Xiaoming Zhang, Jiao Wang,Choushi Wang, Ping Zhou and Xiangdong Chen* (2017) Identification of YfiH and the Catalase CatA As Polyphenol Oxidases of Aeromonas media and CatA as a Regulator of Pigmentation by Its Peroxyl Radical Scavenging Capacity，Fron., Microbiol. 8:1939. doi: 10.3389/fmicb.2017.01939，12pages

8. Yuchen Wang, Linshan Sima, Jie Lv, Suiyuan Huang, Ying Liu, Jiao Wang, Mart Krupovic, Xiangdong Chen*，(2016), Identification, characterization and application of the replicon region of the halophilic temperate sphaerolipovirus SNJ1. J Bacteriol., 198(4):1952-1964

9. Salla T. Jaakkola, Friedhelm Pfeiffer,Janne J. Ravantti, Qinggong Guo,Ying Liu, Xiangdong Chen, Hongling Ma, Chunhe Yang,Hanna M. Oksanen , Dennis H. Bamford*，(2016), The complete genome of a viable archaeum isolated from 123-million-year-old rock salt, Environ. Microbiol. 18(2), 565–579

10. 晋婷婷，付正伟，沈萍，陈向东*，(2016)，枯草芽孢杆菌携带PBSX类缺陷性原噬菌体的普遍性调查，微生物学通报, 43(6): 1244-1252

11. 张春芝（进修教师）、陈贝贝、 雷明瑄、郭庆功、陈向东*，一株奥奈达希瓦氏菌烈性噬菌体的分离、纯化及鉴定，微生物学通报，Sep. 20, 2016, 43(9): 1953?1959

12. Ying Liu, Jiao Wang, Yang Liu, Yuchen Wang, Ziqian Zhang, Hanna M. Oksanen, Dennis H. Bamford and Xiangdong Chen* (2015) Identification and characterization of SNJ2, the first temperate pleolipovirus integrating into the genome of the SNJ1-lysogenic archaeal strain. Mol. Microbiol. 98(6), 1002–1020

13Jie Lv, Shuai Wang, Yuchen Wang, Yuping Huang, Xiangdong Chen*, (2015), Isolation and Molecular Identification of Auxotrophic Mutants to Develop a Genetic Manipulation System for the Haloarchaeon Natrinema sp. J7-2. Archaea Volume 2015, Article ID 483194, 16 pages

14. Yunjun Mei*, Congcong He, Yongchi Huang, Ying Liu, Ziqian Zhang, Xiangdong Chen*, Ping Shen, (2015), Salinity Regulation of the Interaction of Halovirus SNJ1 with Its Host and Alteration of the Halovirus Replication Strategy to Adapt to the Variable Ecosystem. PLoS ONE 10(4): e0123874. doi: 10.1371/journal.pone.0123874. eCollection 2015

15．He Wang, Yunqian Qiao, Baozhong Chai, Chenxi Qiu, Xiangdong Chen* ,(2015), Identification and Molecular Characterization of the Homogentisate Pathway Responsible for Pyomelanin Production, the Major Melanin Constituents in Aeromonas media WS. PLoS ONE 10(3): e0120923. doi:10.1371/journal.pone.0120923

16. Tingting Jin, Xiaoming Zhang, Yang Zhang, Zhongsheng Hu, Zhengwei Fu, Junpeng Fan, Ming Wu, Yi Wang, Ping Shen, Xiangdong Chen* ,(2014), Biological and genomic analysis of a PBSX-like defective phage induced from Bacillus pumilus AB94180. Arch Virol. 159: 739–752

17. Salla T. Jaakkola, Karolin Zerulla, Qinggong Guo, Ying Liu, Hongling Ma, Chunhe Yang, Dennis H. Bamford, Xiangdong Chen* Jorg Soppa*, Hanna M. Oksanen* ,(2014), Halophilic Archaea Cultivated from Surface Sterilized Middle-Late Eocene Rock Salt Are Polyploid，PLOS ONE 9(10):e110533: 1-9

18. Yi Wang, Zhenmin Chen, Ruili Zhao, Tingting Jin, Xiaoming Zhang, Xiangdong Chen*,(2014), Deleting multiple lytic genes enhances biomass yield and production of recombinant proteins by Bacillus subtilis, Microb Cell Fact. 13:129: 1-11

19．柴保中, 王禾, 彭珍荣, 沈萍, 陈向东*,(2014), 细菌黑色素的合成途径及生物功能研究进展，微生物学通报, 41(2): 334-343

20. Jie Lv, Shuai Wang, Chi Zeng, Yuping Huang, Xiangdong Chen*,(2013), Construction of a shuttle expression vector with a promoter functioning in both halophilic Archaea and Bacteria. FEMS Microbiol. Lett. 349,9-15

21. Baozhong Chai, He Wang, Xiangdong Chen*, (2012), Draft Genome Sequence of High-Melanin-Yielding Aeromonas media Strain WS. J. Bacteriol. 194 (23): 6693–6694

22. Ziqian Zhang, Ying Liu, Shuai Wang, Di Yang, Yichen Cheng, Jiani Hu, Jin Chen, Yunjun Mei, Ping Shen, Dennis H. Bamford, Xiangdong Chen*, (2012), Temperate membrane-containing halophilic archaeal virus SNJ1 has a circular dsDNA genome identical to that of plasmid pHH205. Virology. 434: 233–241

23. Hongbo Wei, Shexiao Zou, Xiaolin Yang, Daiqin Yang, Xiangdong Chen*, (2012), Development of multiplex real-time quantitative PCR for simultaneous detection of Chlamydia trachomatis and Ureaplasma parvum，Clin. Biochem. 45(9):663-667.

24. Jing Geng, Peng Yuan, Chun Shao, Sheng-Bing Yu, Bo Zhou, Ping Zhou, Xiang-Dong Chen*, Bacterial melanin interacts with double-stranded DNA with high affinity and may inhibits cell metabolism in vivo, Arch. Microbiol., 2010,192(5):321-329

25. Zhenmin Chen, Qing Li, Huamei Liu, Na Yu, Tianjian Xie, Mingyuan Yang, Ping Shen, Xiangdong Chen*,(2010), Greater enhancement of Bacillus subtilis spore yields in submerged cultures by optimization of medium composition through statistical experimental designs. Appl. Microbiol, Biotech. 85:1353–1360

26. Chi Zeng, Yingzi Zhao, Changzheng Cui, Hao Zhang, Jianyu Zhu, Xiaofeng Tang, Ping Shen, Yuping Huang *, Xixngaodng Chen*, (2009), Characterization of the Haloarcula hispanica amyH gene promoter, an archaeal promoter that confers promoter activity in Escherichia coli， Gene 442(1-2):1-7.

27. Xia. Wan, Baozhong. Chai, Yi. Liao, Ying. Su, Tao. Ye, Ping. Shen, Xiangdong. Chen*,(2009), Molecular and biochemical characterization of a distinct tyrosinase involved in melanin production from Aeromonas media. Appl. Microbiol, Biotech. 82(2):261-9

28. Yunjun. Mei, Dong. Chen, Dongchang. Sun, Yang. Yang, Yuping. Huang, Ping. Shen, and Xiangdong. Chen*,(2008), An Easier Method for Locating Replication Origins Based on Real-Time Polymerase Chain Reaction. Curr Microbiol.,56,633-8

29. Jing. Geng, Wei. Tang, Xia. Wan, Qing. Zhou, Xiaojun. Wang, Ping. Shen, Tiechi. Lei*, Xiangdong. Chen*,（2008）, Photoprotection of bacterial-derived melanin against UVA induced cell death and its potential application as an active sunscreen. J Euro Acade Dermatol Venereol.,22,852-858.

30. Jing. Geng, Shunbing. Yu, Xia. Wan, Xiaojuan. Wang, Ping. Shen, Ping. Zhou, Xiangdong. Chen* ,(2008), Protective action of bacterial melanin against DNA damage in full UV spectrums by a sensitive plasmid-based noncellular system. J Bioch Bioph Meth.,70,1151-1155..

31. Xia. Wan, Huihui. Liu, Yi. Liao, Yi. Su, Jing. Geng, Mingyuan. Yang, Xiangdong. Chen*, Ping Shen, (2007),. Isolation of a novel strain of Aeromonas media producing high levels of DOPA-melanin and assessment of the photoprotective role of the melanin in bioinsecticide applications. J Appl Microbiol.,103,2533–41.

32. Yunjun. Mei, Jing. Chen, Dongchang. Sun, Dong. Chen, Yang. Yang, Ping. Shen, Xiangdong. Chen*,(2007), Induction and primary characterization of a novel halophage SNJ1 from lysogenic Natrinema sp. F5 with mitomycin C. Can. J.Microbiol.,53,1106-1110.

33. Xiaojuan. Wang, Meiju. Li, Qing. Yan, Xiangdong. Chen*, Jing. Geng, Zhixiong. Xie, Ping. Shen, (2007), Across genus plasmid transformation between Bacillus subtilis and Escherichia coli and the effect of Escherichia coli on the transforming ability of free plasmid. Curr Microbiol.,54,450-6.