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杜世燊

领域:生物产业 学校:武汉大学职称:研究员

细菌细胞生长与分裂的机制...

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教育背景

2003.9 — 2007.6   武汉大学生命科学学院生命科学与技术基地班, 生物学学士

2007.8 — 2013.12  美国堪萨斯大学医学中心,微生物学博士

工作经历

2014.2 — 2018.6 堪萨斯大学医学中心博士后

2018.7 — 2019.6 堪萨斯大学医学中心研究助理教授

项目课题经历

论文、成果、著作等

1.Shishen Du, Wyatt Henke, Sebastien Pichoff, Joe Lutkenhaus*. (2019) How FtsEX localizes to the Z ring and interacts with FtsA to regulate cell division. Mol Microbiol [Epub ahead of print]


2.Shishen Du, Joe Lutkenhaus*. (2019) At the heart of bacterial cytokinesis: the Z ring. Trends Microbiol S0966-842X(19)30122-2


3.Qinggong Guo, Beibei Chen, Yishuai Tu, Shishen Du*, and Xiangdong Chen*. (2019) Prophage LambdaSo uses replication interference to suppress reproduction of co-existing temperate phage MuSo2 in Shewanella oneidensis MR-1. Environ Microbiol 21(6)2079-2094


4.Yunqian Qiao, Jiao Wang, He Wang, Baozhong Chai, Chufeng Rao, Xiangdong Chen* and Shishen Du*. (2018) 4-hydroxyphenylpyruvate dioxygenase thermolability is responsible for temperature-dependent melanogenesis in Aeromonas Salmonicida subsp. Salmonicida. Appl Environ Microbiol 13; 85 (1). pii::e01926-18


5.Shishen Du, Sebastien Pichoff, Kruse K and Joe Lutkenahus. (2018) FtsZ filaments have the opposite kinetic polarity of microtubules. Proc Natl Acad Sci USA 115(42):10768-10773 (Faculty of 1000)


6.Sebastien Pichoff#, Shishen Du# and Joe Lutkenhaus. (2018) Disruption of divisome assembly rescued by FtsN-FtsA interaction in E. coli. Proc Natl Acad Sci USA 115(29):E6855-E6862 (#:equal contribution)


7.Kyung-Tae Park, Alex Dajkovic, Mark Wissel, Shishen Du and Joe Lutkenhaus*. (2018) MinC and FtsZ mutant analysis provides insight into MinC/MinD-mediated Z Ring disassembly. J Biol Chem. 293(16)::5834-5846


8.Joe Lutkenhaus*, and Shishen Du. (2017) E. coli Cell cycle Machinery. Subcell Biochem 84: 27-65


9.Shishen Du, and Joe Lutkenhaus*. (2017) The N-succinyl-ll-diaminopimelic acid desuccinylase acts through ZapB to promote septum formation in Escherichia coli. Mol Microbiol 105(2):326-345 (Faculty 1000)


10.Shishen Du, and Joe Lutkenhaus*. (2017) Assembly and activation of the Escherichia coli divisome. Mol Microbiol 105(2):177-187


11.Shishen Du, Sebastien Pichoff, and Joe Lutkenhaus*. (2016) FtsEX acts on FtsA to regulate divisome assembly and activation in E. coli. Proc Natl Acad Sci USA 113 (34):E5052-61(Faculty 1000)


12.Kyung-Tae Park, Shishen Du, and Joe Lutkenhaus*. (2015) MinC/MinD copolymers are not required for Min function. Mol Microbiol 98 (5): 895-909


13.Sebastien Pichoff, Shishen Du, and Joe Lutkenhaus*. (2015) The bypass of ZipA by overexpression of FtsN requires a previously unknown conserved FtsN motif essential for FtsA-FtsN interaction supporting a model in which FtsA monomers recruit late cell division proteins to the Z ring. Mol Microbiol 95 (6): 971-987


14.Shishen Du, Kyung-Tae Park, and Joe Lutkenhaus*. (2015) Oligomerization of FtsZ converts the FtsZ tail motif (Conserved carboxy-terminal peptide) into a multivalent ligand with high avidity for partners ZipA and SlmA. Mol Microbiol 95 (2): 173-188


15.Shishen Du, and Joe Lutkenhaus*. (2014) SlmA antagonism of FtsZ ring assembly employs a two-pronged mechanism like MinCD. PloS Genetics 10.1371-e1004460


16.Joe Lutkenhaus*, Sebastien Pichoff, and Shishen Du. (2012) Bacterial cytokinesis: From Z ring to divisome. Cytoskeleton (Hoboken) 69: 778-790


17.Shishen Du, and Joe Lutkenhaus*. (2012) MipZ: One for the Pole, Two for the DNA. Molecular Cell 46: 239-240

专利、著作版权等

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