2002-2004 匹兹堡大学医学院儿童医院血液与肿瘤学系　博士后
1996-2001 中南大学湘雅医学院肿瘤研究所　　　　　　硕-博士
1992-1996 湖南师范大学生物系　　　　　　　　　　　学士

2011—至今　湖北省楚天学者计划特聘教授
2010—至今　武汉大学生命科学学院　　　　　　　　　　教授,博士生导师
2007-2010　 匹兹堡大学医学院儿童医院血液与肿瘤学系　研究助理教授
2004-2007　 匹兹堡大学儿童医院血液与肿瘤学系　　　　高级研究助理
2001-2002　 中南大学湘雅医学院肿瘤研究所　　　　　　讲师

国家自然科学基金面上项目，2018/1-2021/12，主持
国家重点研发计划，2016/9-2020/12， 学术骨干
国家自然科学基金面上项目，2015/1-2018/12，主持
国家重大科学研究计划，2014/1-2018/12，学术骨干
国家重大科学研究计划，2012/1-2016/12，学术骨干
国家自然科学基金面上项目，2012/1-2015/12，主持
国家自然科学基金面上项目，2011/1-2013/12，主持
教育部博士点博导类科研基金，2012/1-2014/12，主持
湖北省自然科学基金面上项目，2011/1-2012/12，主持

代表性论文：
1. Gu L, Zhu Y, Lin X, Li Y, Cui K, Prochownik EV, Li Y* (2018). Amplification of glyceronephosphate O-acyltransferase and recruitment of USP30 stabilize DRP1 to promote hepatocarcinogenesis. Cancer Research, 78:5808-5819.

2. Li W, Cui K, Prochownik EV, Li Y* (2018). The deubiquitinase USP21 stabilizes MEK2 to promote tumor growth. Cell Death & Disease 9: 482. doi: 10.1038/s41419-018-0523.

3. Zhu Y, Gu L, Li Y, Lin X, Shen H, Cui K, Chen L, Zhou F, Zhao Q, Zhang J, Zhong B, Prochownik E, Li Y*(2017). MiR-148a inhibits colitis and colitis-associated tumorigenesis in mice. Cell Death & Differentation doi:10.1038/cdd.2017.151.

4. Shen H, Xing C, Cui K, Li Y, Zhang J, Du R, Zhang X, Li Y*(2017). MicroRNA-30a attenuates mutant KRAS-driven colorectal tumorigenesis via direct suppression of ME1. Cell Death & Differentation 24:1253-1262.

5. Cheng L, Zhu Y, Han H, Zhang Q, Cui K, Shen H, Zhang J, Yan J, Prochownik E, Li Y*(2017). MicroRNA-148a deficiency promotes hepatic lipid metabolism and hepatocarcinogenesis in mice. Cell Death & Disease 8:e2916.

6. Kulkarni S, Dolezal JM, Wang H, Jackson L, Lu J, Frodey BP, Dosunmu-Ogunbi A, Li Y, Fromherz M, Kang A, Santana-Santos L, Benos PV, Prochownik EV*(2017). Ribosomopathy-like properties of murine and human cancers. PLoS One 12:e0182705.

7. Han H, Chen Y, Cheng L, Prochownik EV, Li Y*(2016). microRNA-206 impairs c-Myc-driven cancer in a synthetic lethal manner by directly inhibiting MAP3K13. Oncotarget 7:16409-16419.

8. Han H, Li W, Shen H, Zhang J, Zhu Y, Li Y*(2016). microRNA-129-5p, a c-Myc negative target, affects hepatocellular carcinoma progression by blocking the Warburg effect. J Mol Cell Biol. 8:400-410.

9. Li Y*, Zhu Y, Prochownik EV. (2016) MicroRNA-based screens for synthetic lethal interactions with c-Myc. RNA Disease 3. pii: e1330.

10. Shen H, Li W, Tian Y, Xu P, Wang H, Zhang J, Li Y*(2015).Upregulation of miR-362-3p Modulates Proliferation and Anchorage-Independent Growth by Directly Targeting Tob 2 in Hepatocellular Carcinoma. Journal of Cellular Biochemistry 8:1563–1573.

11. Lu L, Han H, Tian Y, Li W, Zhang J, Feng M, Li Y*(2015). Aurora kinase A mediates c-Myc's oncogenic effects in hepatocellular carcinoma. Molecular Carcinogenesis 11:1467–1479.

12. Han H, Sun D, Li W, Shen H, Zhu Y, Li C, Chen Y, Lu L, Li W, Zhang J, Tian Y and Li Y*(2013). A c-Myc-MicroRNA functional feedback loop affects hepatocarcinogenesis. Hepatology 6:2378–2389.

13. Wu Q, Xu FL, Li Y, Prochownik EV, Saunders WS*(2010). The c-Myc target Glycoprotein1balpha links cytokinesis failure to oncogenic signal transduction pathways in cultured human cells. PLoS One 5:10819-10825.

14. Li Y, Xu FL, Lu J, Saunders WS, Prochownik EV*(2010). Widespread genomic instability mediated by a pathway involving glycoprotein Ib alpha and Aurora B kinase. J Biol Chem 17: 13183-13192.

15. Li Y, Lu J, Prochownik EV*(2009). Modularity of the oncoprotein-like properties of platelet glycoprotein Ibalpha. J Biol Chem 3: 1410-1418.

16. Li Y, Lu J, Cohen D, Prochownik EV*(2008). Transformation, genomic instability and senescence mediated by platelet/megakaryocyte glycoprotein Ibalpha. Oncogene 11:1599–1609.

17. Prochownik EV, Li Y (2007). The ever expanding role for c-Myc in promoting genomic instability. Cell Cycle 9:1024-1033.

18. Li Y, Lu J, Prochownik EV*(2007). c-Myc-mediated genomic instability proceeds via a megakaryocytic endomitosis pathway involving Gp1balpha. Proc Natl Acad Sci USA 9:3490-3495.

19. Li Y, Lu J, Prochownik EV*(2007). Dual role for SUMO E2 conjugase Ubc 9 in modulating the transforming and growth-promoting properties of the HMGA1b architectural transcription factor. J Biol Chem 18:13363-13434.

20. Li Y, Rogulski K, Zhou Q, Sims PJ, Prochownik EV*(2006). The negative c-Myc target onzin affects proliferation and apoptosis via its obligate interaction with phospholipid scramblase 1. Mol Cell Biol 9:3401-3444.

21. Rogulski K, Li Y, Rothermund K, Pu L, Watkins S, Yi F, Prochownik EV*(2005). Onzin, a c-Myc-repressed target, promotes survival and transformation by modulating the Akt-Mdm2-p53 pathway. Oncogene 51:7524-7565.

22. Li Y, Chen Z*(2004). Molecular cloning and characterization of LCRG1, a novel gene localized to the tumor suppressor locus D17S800-D17S930. Cancer Lett 1:75-85. .