2008 – 2013　贝勒医学院 博士后
2005 – 2008　路易斯安那州立大学 博士后
1998 – 2004　武汉大学生命科学学院 博士

2018.04 – 至今 武汉大学生命科学学院院长助理
2015.09 – 至今 武汉大学高等研究院兼职研究员
2015.05 – 至今 武汉大学生命科学学院遗传学系主任
2014.03 – 至今 武汉大学生命科学学院，教授，博士生导师

1. 中组部青年千人计划项目：2014-2017
2. 国家重大基础研究计划子项目（973）：2015-2019
3. 国家自然科学基金面上项目：（No.31471217, 2014-2018；No.31671294, 2016-2020；No.31872808, 2019-2022）

代表性论文：
1. Sihao Zheng, Dan Li, Zhen Lu, Guangxue Liu, Meng Wang, Poyuan Xing, Min Wang, Yang Dong, Xuejie Wang, Jingyao Li, Simin Zhang, Haoyang Peng, Grzegorz Ira, Guohong Li, Xuefeng Chen#. Bre1-dependent H2B ubiquitination promotes homologous recombination by stimulating histone eviction at DNA breaks. Nucleic Acids Research, 2018.09 (In press, corresponding author)

2. Shuqi Li,Zhiyun Xu,Jiawei Xu,Linyu Zuo,Chuanhe Yu,Pu Zheng,Haiyun Gan,Xuezheng Wang,Longtu Li,Sushma Sharma,Andrei Chabes,Di Li,Sheng Wang,Sihao Zheng,Jinbao Li,Xuefeng Chen,Yujie Sun,Dongyi Xu,Junhong Han,Kuiming Chan,Zhi Qi,Jianxun Feng,Qing Li. Rtt105 functions as a chaperone for replication protein A to preserve genome stability. The EMBO Journal, 2018,37,e99154
　　
3. Zhen Wang, Qiao-Yun Long, Lin Chen, Jia-Dong Fan, Zhao-Ning Wang, Lian-Yun Li#, Min Wu#, Xuefeng Chen#. Inhibition of H3K4 demethylation induces autophagy in cancer cell lines. BBA-Molecular Cell Research, 2017, 1864:2428–2437 (# Co-corresponding author)
　　
4. Xin Zhao,Chengwen Wei,Jingjing Li,Poyuan Xing,Jingyao Li,Sihao Zheng and Xuefeng Chen#. Cell cycle-dependent control of homologous recombination. Acta Biochimica et Biophysica Sinica, 2017, 49(8): 655–668 (Invited review, corresponding author)
　　
5. Xuefeng Chen#, Hengyao Niu, Yang Yu, Jingjing Wang, Shuangyi Zhu, Jianjie Zhou, Alma Papusha, Dandan Cui, Xuewen Pan, Youngho Kwon, Patrick Sun# and Grzegorz Ira#. Enrichment of Cdk1-cyclins at DNA double-strand breaks stimulates Fun30 phosphorylation and DNA end resection. Nucleic Acids Research, 2016, 44: 2742-2753 (# Co-corresponding author)
　　
6. Wenchao Huang, Changchun Yu, Jun Hu, Lili Wang, Zhiwu Dan, Wei Zhou, Chunlan He, Yafei Zeng, Guoxin Yao, Jianzhao Qi, Zhihong Zhang, Renshan Zhu, Xuefeng Chen and Yingguo Zhu. Pentatricopeptide-repeat family protein RF6 functions with hexokinase 6 to rescue rice cytoplasmic male sterility. Proc. Natl. Acad. Sci. USA, 2015, 112: 14984–14989

7. Marenda A. Wilson, YoungHo Kwon, Yuanyuan Xu, Woo-Hyun Chung, Peter Chi, Hengyao Niu, Ryan Mayle, Xuefeng Chen, Anna Malkova, Patrick Sung & Grzegorz Ira. Pif1 helicase and Polδ promote recombination-coupled DNA synthesis via bubble migration. Nature, 2013, 502(7471):393-396

8. Xuefeng Chen, Dandan Cui, Alma Papusha, Xiaotian Zhang, Chia-Dwo Chu, Jiangwu Tang, Kaifu Chen, Xuewen Pan and Grzegorz Ira. The Fun30 ATP-dependent nucleosome remodeler promotes resection of DNA double-strand break ends. Nature, 2012, 489(7417): 576-580
　　
9. Xuefeng Chen, Hengyao Niu, Woo-Hyun Chung, Zhu Zhu, Alma Papusha, Eun Yong Shim, Sang Eun Lee, Patrick Sung and Grzegorz Ira. Cell cycle regulation of DNA double-strand break end resection by Cdk1-dependent Dna2 phosphorylation. Nature Structural & Molecular Biology, 2011, 18(9):1015-1019
　　
10. Xuefeng Chen, Baojin Ding, Danielle LeJeune, Christine Ruggiero, Shisheng Li. Rpb1 sumoylation in response to UV radiation or transcriptional impairment in yeast. PLoS ONE, 2009, 4(4): e5267
　　
11. Danielle LeJeune,Xuefeng Chen,Christine Ruggiero,Shannon Berryhill,Baojin Ding,Shisheng Li. Yeast Elc1 plays an important role in global genomic repair but not in transcription coupled repair. DNA Repair, 2009, 8(1): 40-50
　　
12. Baojin Ding, Christine Ruggiero, Xuefeng Chen, Shisheng Li. Tfb5 is partially dispensable for Rad26 mediated transcription coupled nucleotide excision repair in yeast. DNA Repair, 2007, 6(11):1661-1669
　　
13. Xuefeng Chen, Christine Ruggiero, Shisheng Li. Yeast Rpb9 plays an important role in ubiquitylation and degradation of Rpb1 in response to UV induced DNA damage. Molecular and Cellular Biology, 2007, 27: 4617–4625
　　
14. Shisheng Li, Baojing Ding, Christine Ruggiero, Xuefeng Chen and Michael J. Smerdon. The roles of Rad16 and Rad26 in repairing repressed and actively transcribed genes in yeast. DNA Repair, 2007, 6(11):1596-1606
　　
15. Shisheng Li, Xuefeng Chen, Christine Ruggiero, Baojing Ding, and Michael J. Smerdon. Modulation of Rad26- and Rpb9-mediated DNA repair by different promoter elements. Journal of Biological Chemistry, 2006, 281(48): 36643-36651

16. Shisheng Li, Baojing. Ding, Runqiang. Chen, Christine Ruggiero and Xuefeng Chen. Evidence that the transcription elongation function of Rpb9 is involved in transcription-coupled DNA repair in Saccharomyces cerevisiae. Molecular and Cellular Biology, 2006, 26(24): 9430-9441.