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周荣家

领域:生物产业 学校:武汉大学职称:教授

动物及人类分子发育遗传学...

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教育背景

1978-82和86年四川农业大学取得学士和硕士学位


1989-92华西医科大学取得博士学位

1992-94武汉大学生物(遗传)学博士后

1994.9-12美国加州大学旧金山分校(UCSF)访问学习

1996.6-8 澳大利亚Latrobe 大学访问学习
1996.10-97.5 美国Louisiana州立大学访问学习

1998.11-99.11 法国人类遗传学研究所(CNRS)访问学习

2002.12-03.3 法国巴斯德研究所(Pasteur)访问学习

2006.5. 香港大学 客座教授

工作经历

1996年起任武汉大学教授

1998年起评为博士生导师

项目课题经历

国家重点基础研究发展规划(973)、国家科技支撑计划、转基因重大专项、国家自然科学基金、教育部新世纪优秀人才计划、教育部科技研究重点项目和武汉市学科带头人计划等资助。

论文、成果、著作等

代表论文和著作
1. Sheng Y., Song Y., Li Z., Wang Y., Lin H., Cheng H., Zhou R., RAB37 interacts directly with ATG5 and promotes autophagosome formation via regulating ATG5-12-16 complex assembly. Cell Death Differ. 2018; 25(5):918-934.

2. Song Y., Shang D., Cheng H., Zhou R., The small GTPase RAB37 functions as an organizer for autophagosome biogenesis. Autophagy. 2018; 14(4): 702-714.

3. Zhao X, Luo M, Li Z, Zhong P, Cheng Y, Lai F, Wang X, Min J, Bai M, Yang Y, Cheng H, Zhou R., Chromosome-scale assembly of the Monopterus genome. Gigascience. 2018;7(5):1-9.

4. Liu J., Shang D., Xiao Y., Zhong P., Cheng H., Zhou R., Isolation and characterization of string-forming female germline stem cells from ovaries of neonatal mice. J. Biol. Chem. 2017; 292(39):16003-16013.

5. Luo M, Zhao X, Song Y, Cheng H, Zhou R., Nuclear autophagy: An evolutionarily conserved mechanism of nuclear degradation in the cytoplasm. Autophagy. 2016;12(11):1973-1983.

6. Xiao Y, Gao M, Gao L, Zhao Y, Hong Q, Li Z, Yao J, Cheng H, Zhou R., Directed Differentiation of Zebrafish Pluripotent Embryonic Cells to Functional Cardiomyocytes. Stem Cell Reports. 2016;7(3):370-82.

7. Yuan J., Zhang Y., Sheng Y., Fu X., Cheng H., Zhou R., MYBL2 guides autophagy suppressor VDAC2 to the developing ovary to inhibit autophagy through a complex of VDAC2 /BECN1/ BCL2L1 in mammals. Autophagy, 2015, 11(7):1081-1098.

8. Fu X., Cheng Y., Yuan J., Huang C., Cheng H., Zhou R., Loss-of-function mutation in the X-linked TBX22 promoter disrupts an ETS-1 binding site and leads to cleft palate. Hum. Genet. 2015, 134(2):147-158.

9. Chen K., Huang C., Yuan J., Cheng H., Zhou R., Long-term artificial selection reveals a role of TCTP in autophagy in mammalian cells. Mol Biol Evol. 2014,31(8):2194-211.

10. Zuo Z, Peng D, Yin X, Zhou X, Cheng H, Zhou R., Genome-Wide Analysis Reveals Origin of Transfer RNA Genes from tRNA Halves. Mol Biol Evol. 2013,30(9):2087-98.

11. Hou Y, Yuan J, Zhou X, Fu X, Cheng H, Zhou R., DNA Demethylation and USF Regulate the Meiosis-Specific Expression of the Mouse Miwi. PLoS Genet. 2012;8(5):e1002716.

12. Zhou F, Zhao W, Zuo Z, Sheng Y, Zhou X, Hou Y, Cheng H, Zhou R., Characterization of androgen receptor structure and nucleocytoplasmic shuttling of the rice field eel. J. Biol. Chem. 2010, 285(47):37030-40.

13. Zhou X, Zuo Z, Zhou F, Zhao W, Sakaguchi Y, Suzuki T, Suzuki T, Cheng H, Zhou R., Profiling sex-specific piRNAs in zebrafish. Genetics. 2010,186(4):1175-85.

14. Ying M, Chen B, Tiana Y, Hou Y, Li Q, Shang X, Sun J, Cheng H., Zhou R., Nuclear import of human sexual regulator DMRT1 is mediated by importin-β. BBA Mol. Cell Res. 2007, 1773(6):804-813.

15. Huang X, Guo Y, Shui Y, Gao S, Yu H,, Cheng H., Zhou R., Multiple alternative splicing and differential expression of Dmrt1 in gonad transformation during sex reversal of the rice field eel. Biol. Reprod. 2005, 73: 1017–1024.

16. Cheng H., Ying m., Tian Y., Guo Y., McElreavey K., Zhou R., Transcriptional diversity of DMRT1 (dsx- and mab3-related transcription factor 1) in human testis. Cell Res. 2006, 16:389-393.

17. Zhou R., N. Bonneaud, C-X Yuan, P. de Barbara, B Boizet, S Tibor, G Scherer, RG Roeder, F Poulat, P Berta, SOX9 interacts with a component of the human thyroid hormone receptor-associated protein complex. Nucleic Acids Res. 2002, 30(14): 3245-52.

18. 周荣家,程汉华,编著《转基因动物技术与应用》,武汉大学出版社,1997。

19. 周荣家等,译著《发育原理》,高等教育出版社,2009。

专利、著作版权等

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