2003.9- 2008.7: 博士 中国科学院生物物理研究所 （导师：徐涛）
1999.9- 2003.7: 学士 南开大学生物物理系

2015-至今: 教授，武汉大学生命科学学院。珞珈特聘教授、湖北省“百人计划”青年学者
2008-2015: 博士后，霍华德休斯医学院（HHMI）& 德克萨斯大学西南医学中心 (导师: Helen Hobbs。美国科学院、医学院、艺术与科学学院院士) 。

2007.11-2008.1: 访问学者。 加拿大多伦多大学。

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发表论文:
1) Zhang YY, Fu ZY, Wei J, Qi W, Baituola G, Luo J, Meng YJ, Guo SY, Yin H, Jiang SY, Li YF, Miao HH, Liu Y, Wang Y, Li BL, Ma YT#, Song BL#. A LIMA1 variant promotes low plasma LDL cholesterol and decreases intestinal cholesterol absorption. Science. 2018 Jun 8;360(6393):1087-1092

2) Xue W, Huang J, Chen H, Zhang Y, Zhu X, Li J, Zhang W, Yuan Y, Wang Y, Zheng L*, Huang K*. Histone methyltransferase G9a modulates hepatic insulin signaling via regulating HMGA1. BBA-Molecular Basis of Disease, 2018; 1864(2):338-346.


3) Hu A, Zhao XT, Tu H, Xiao T, Fu T, Wang Y, Liu Y, Shi XJ, Luo J*, Song BL*. PIP4K2A regulates intracellular cholesterol transport through modulating PI(4,5)P2 homeostasis. J Lipid Res. 2018 Mar;59(3):507-514


4) Wu Y, Shan B, Dai J, Wang X, Xia Z, Cai J, Chen T, Lv S, Feng Y, Zheng L, Wang Y, Liu JF, Fang J, Xie D, Rui L, Liu JM, Liu Y*. (2018) Dual Role for Inositol-requiring Enzyme 1α in Promoting the Development of Hepatocellular Carcinoma during Diet-induced Obesity. Hepatology. 2018 Aug;68(2):533-546.


5) Fu T, Guan YY, Xu JJ, Wang Y#. APP, APLP2 and LRP1 interact with PCSK9 but are not required for PCSK9-mediated degradation of the LDLR in vivo. BBA - Molecular and Cell Biology of Lipids. 2017 Sep;1862(9):883-889


6) Xie C, Zhang YP, Song L, Luo J, Qi W, Hu J, Lu D, Yang Z, Zhang J, Xiao J, Zhou B, Du JL, Jing N, Liu Y, Wang Y, Li B, Song BL*, Yan Y*. Genome editing with CRISPR/Cas9 in postnatal mice corrects PRKAG2 cardiac syndrome. Cell Res. 2016 Oct;26(10):1099-1111.


7) Wang Y, McNutt M, Banfi S, Levin M, Holland W, Gusarova V, Gromada J, Cohen JC, Hobbs HH. Hepatic ANGPTL3 Regulates Adipose Tissue Energy Homeostasis. Proc Natl Acad Sci U S A. 2015 Sep 15;112(37):11630-5.


8) Wang Y, Gusarova V, Banfi S, Gromada J, Valenzuela D, Cohen JC, Hobbs HH. Inactivation of ANGPTL3 Reduces Hepatic VLDL-triglyceride Secretion. J Lipid Res. 2015 Jul;56(7):1308-17.


9) Gusarova V, Alexa CA, Wang Y, Rafique A, Kim JH, Buckler D, Mintah IJ, Shihanian LM, Cohen JC, Hobbs HH, Xin Y, Valenzuela DM, Murphy AJ, Yancopoulos GD, Gromada J. ANGPTL3 blockade with a human monoclonal antibody reduces plasma lipids in dyslipidemic mice and monkeys. J Lipid Res. 2015 Jul;56(7):1308-17


10) Wang Y*, Quagliarini F*, Gusarova V, Gromada J, Valenzuela D, Cohen JC, Hobbs HH. Mice Lacking ANGPTL8 (Betatrophin) Manifest Disrupted Triglyceride Metabolism Without Impaired Glucose Homeostasis. Proc Natl Acad Sci U S A. 2013 Oct 1. 110(40):16109-14


11) Quagliarini F*, Wang Y*, Kozlitina J, Grishin N, Hyde R, Boerwinkle E, Cohen JC, Hobbs HH . Atypical angiopoietin-like protein that regulates ANGPTL3. Proc Natl Acad Sci U S A. 2012 Nov 27. 109(48):19751-6


12) Wang Y, Huang Y, Hobbs HH, Cohen JC. Molecular characterization of proprotein convertase subtilisin/kexin type 9-mediated degradation of the LDLR. J Lipid Res. 2012 Sep;53(9):1932-43.


13) Bai L*, Wang Y*, Fan J*, Chen Y, Ji W, Qu A, Xu P, James DE & Xu T Dissecting multiple steps of GLUT4 trafficking and identifying the sites of insulin action. Cell Metab. 2007 Jan;5(1):47-57


14) Chen Y*, Wang Y*, Zhang J*, Deng Y, Jiang L, Song E, Wu XS, Hammer JA, Xu T, Lippincott-Schwartz J. Rab10 and myosin-Va mediate insulin-stimulated GLUT4 storage vesicle translocation in adipocytes. J Cell Biol. 2012 Aug 20;198(4):545-60


15) Wang Y*, Zhang J*, Chen Y*, Jiang L, Ji W, Xu T. Characterization of GLUT4-containing vesicles in 3T3-L1 adipocytes by total internal reflection fluorescence microscopy. Sci China C Life Sci. 2009 Jul; 52(7):665-71


16) Chen Y*, Wang Y*, Ji W*, Xu P, Xu T. A pre-docking role for microtubules in insulin-stimulated glucose transporter 4 translocation. FEBS J. 2008 Feb;275(4):705-12


17) Jiang L, Fan J, Bai L, Wang Y, Chen T, Yang L, Chen L, Xu T. Direct quantification of fusion rate reveals a distal role for AS160 in insulin stimulated fusion of GLUT4 storage vesicles. J Biol Chem. 2008 Mar 28; 283(13):8508-16


18) Bai L, Zhu D, Zhou K, Zhou W, Li D, Wang Y, Zhang R, Xu T (2006) Differential Properties of GTP- and Ca2+-Stimulated Exocytosis from Large Dense Core Vesicles. Traffic, 2006 Apr;7(4):416-28.