教育背景
1998-2002:兰州大学化学化工学院,学士
2005-2010:兰州大学化学化工学院,博士(导师:涂永强院士)
工作经历
2002-2010:兰州大学功能有机分子化学国家重点实验室
2010-2011:美国芝加哥大学(Chicago University)化学系,博士后(导师:何川教授)
2011-2014:美国宾夕法尼亚州立大学(Penn State University)化学系,博士后(导师:陈弓教授)
2015- : 上海交通大学化学化工学院,特别研究员
项目课题经历
论文、成果、著作等
2019
1) Highly atroposelective synthesis of nonbiaryl naphthalene-1,2-diamine N-C atropisomers through direct enantioselective C-H amination
H.-Y. Bai, F.-X. Tan, T.-Q. Liu, G.-D. Zhu, J.-M. Tian, T.-M. Ding, Z.-M. Chen, S.-Y. Zhang*
Nature Commun. 2019, 10. 3063. (Editors' Highlights)
2) Electrochemical Halogenation/Semi-pinacol Rearrangement of Allylic Alcohols Using Inorganic Halide Salt: An Eco-friendly Route to Synthesis of β-halocarbonyls
C. Chen, J.-C. Kang, C. Mao, J.-W. Dong, Y.-Y. Xie, T.-M. Ding, Y.-Q. Tu, Z.-M. Chen* and S.-Y. Zhang*
Green Chem. 2019, 21, 4014. (Inside front cover)
3) Asymmetric N-hydroxyalkylaltion of Indoles with Ethyl Glyoxalates Catalyzed by a Chiral Phosphoric Acid: Highly Enantioselective Synthesis of Chiral N,O-aminal Indole Derivatives
L. Wang, J. Zhou, T.-M. Ding, Z.-Q. Yan, G.-D. Zhu,* and S.-Y. Zhang*
Org. Lett. 2019, 21, 2795.
4) Electrochemical Semipinacol Rearrangements of Allylic Alcohols: Construction of All-Carbon Quaternary Stereocenters
J.-C. Kang, Y.-Q. Tu, J.-W. Dong, C. Chen, J. Zhou, T.-M. Ding, J.-T. Zai, Z.-M. Chen,* and S.-Y. Zhang*
Org. Lett. 2019, 21, 2536. (Most downloaded)
5) Dual Directing Groups-Assisted Redox-Neutral Annulation and Ring-Opening of N-Aryloxyacetamides with 1-Alkynylcyclobutanols via Rhodium(III)-Catalyzed C–H/C–C Activations
J.-L. Pan, C. Liu, C. Chen, T.-Q. Liu, M. Wang, Z. Sun* and S.-Y. Zhang*
Org. Lett. 2019, 21, 2823.
6) Asymmetric Organocatalytic Synthesis of 2,3-Allenamides from Hydrogen Bond-Stabilized EnynamidesZ.-G. Ma, J.-L. Wei, J.-B. Lin, G.-J. Wang, J. Zhou, K. Chen, C.-A. Fan* and S.-Y. Zhang*
Org. Lett. 2019, 21, 2468.
7) Computational and Experimental Studies on Copper-Catalyzed Selective Cascade C-H/N-H Annulation of Electron-Deficient Acrylamide with Arynes
C. Chen, Y. Hao, T.-Y. Zhang, J.-L. Pan, J. Ding, H.-Y. Xiang, M. Wang, T.-M. Ding, A. Duan,* S.-Y. Zhang*
Chem. Commun. 2019, 55, 755. (Inside front cover designed by Chen Mao, freshman at SJTU)
2018
1) Rhodium(III)-Catalyzed Redox-Neutral Cascade [3 + 2] Annulation of N‑Phenoxyacetamides with Propiolates via C−H Functionalization/Isomerization/Lactonization
J.-L. Pan, P. Xie, C. Chen, Y. Hao, C. Liu, H.-Y. Bai, J. Ding, L.-R. Wang, Y. Xia,* and S.-Y. Zhang*
Org. Lett. 2018, 20, 7131.
2) A Facile Approach to Oximes and Ethers by aTandem NO+-Initiated Semipinacol Rearrangement and H-Elimination
J.-W. Dong, T.-M. Ding, S.-Y. Zhang,* Z.-M. Chen,* and Y.-Q. Tu*
Angew. Chem. Int. Ed. 2018, 57, 13192.
3) Transition Metal-Controlled Direct Regioselective Intermolecular Amidation of C−H Bonds with Azodicarboxylates: Scope, Mechanistic Studies, and Applications
H.-Y. Bai, X. Fu, J.-L. Pan, H.-Q. Ma, Z.-M. Chen, T.-M. Ding,* and S.-Y. Zhang*
Adv. Synth. Catal. 2018, 360, 4205. (Full Paper)
4) Experimental and computational studies on H2O-promoted, Rh-catalyzed transient-ligand free ortho-C(sp2)–H amidation of benzaldehydes with dioxazolones
J. Ding, W. Jiang, H.-Y. Bai, T.-M. Ding, D. Gao, X. Bao* and S.-Y. Zhang *
Chem. Commun. 2018, 54, 8889.
5) Metal-Controlled, Regioselective, Direct Intermolecular α- or γ‑Amination with Azodicarboxylates
X. Fu, H.-Y. Bai, G.-D. Zhu, Y. Huang,* and S.-Y. Zhang*
Org. Lett. 2018, 20, 3469.
6) Copper-Mediated Cascade C−H/N−H Annulation of Indolocarboxamides with Arynes: Construction of Tetracyclic Indoloquinoline Alkaloids
T.-Y. Zhang, C. Liu, C. Chen, J.-X. Liu, H.-Y. Xiang, W. Jiang, T.-M. Ding, S.-Y. Zhang*
Org. Lett. 2018, 20, 220.
7) Mechanistic insights into staphylopine-mediated metal acquisition
L. Song, Y. Zhang, W. Chen, T. Gu, S.-Y. Zhang, and Q. Ji*
PNAS, 2018, 115, 3942.
8) Recent progress in the isolation, bioactivity, biosynthesis, and total synthesis of natural spiroketals
F.-M. Zhang, S.-Y. Zhang and Y.-Q. Tu*
Nat. Prod. Rep. 2018, 35, 75.
2017
1) Stereoselective Synthesis of Z Vinylsilanes via Palladium-Catalyzed Direct Intermolecular Silylation of C(sp2)−H Bonds
J.-L. Pan, C. Chen, Z.-G. Ma, J. Zhou, L.-R. Wang, S.-Y. Zhang*
Org. Lett. 2017, 19, 5216.
2) Copper-Catalyzed Selective ortho-C−H/N−H Annulation of Benzamides with Arynes: Synthesis of Phenanthridinone Alkaloids
T.-Y. Zhang, J.-B. Lin, Q.-Z. Li, J.-C. Kang, J.-L. Pan, S.-H. Hou, C. Chen, S.-Y. Zhang*
Org. Lett. 2017, 19, 1764.
3) Palladium-Catalyzed Direct Intermolecular Amination of Unactivated Methylene C(sp3)−H Bonds with Azodiformates via Bidentate-Chelation Assistance
H.-Y. Bai, Z.-G. Ma, M. Yi, J.-B. Lin, S.-Y. Zhang*
ACS Catal. 2017, 7, 2042.
2016
1) Palladium-catalyzed direct intermolecular silylation of remote unactivated C(sp3)-H bonds
J.-L. Pan, Q.-Z. Li, T.-Y. Zhang, S.-H. Hou, J.-C. Kang, S.-Y. Zhang*
Chem. Commun. 2016, 52 , 13151.
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