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王进

领域:新材料产业 学校:西南交通大学职称:教授

现主要研究方向: (1) 生物医用高分子材料的制备、改性和性能评价; (2) 心血管人工器官和植介入器械的制造 (3) 材料表面与界面研究...

具体了解该专家信息,请致电:027-87555799 邮箱 haizhi@uipplus.com

教育背景

1986-1990:南京大学化学系高分子合成专业、本科; 1990-1994:成都无线电一厂,助理工程师 1994 – 1999:四川大学,材料学,硕博连读 2000-2002:西南交通大学材料学院,讲师; 2003.3-2003.9:香港城市大学访问学者;

工作经历

项目课题经历

目前主持的科研项目有: 1、等离子体聚氧乙烯功能化薄膜的合成及其抗生物粘附特性研究(51173149)60万元,国家自然科学基金(主持),2012.1-2015.12 2、时序功能性血管支架与植入周围环境的相互作用与调控(81330031)290万元,国家自然科学基金重点项目(主研),2014.1-2018.12 3、材料诱导干细胞定向分化的微环境及其构建(2011CB606204)184万元,国家重点基础研究发展(973计划)(主研),2011.1-2015.12 已结题的科研项目: 1、医用金属器械表面具有生物化功能的等离子体聚合薄膜的构建及生物医学行为研究(NCET-07-0715)50万元,教育部新世纪优秀人才支持计划(主持),2008.1-2010.12 2、介入器械表面等离子体聚合薄膜的抗凝血结构设计与控制(50673081)28万元,国家自然科学基金(主持),2007.1-2009.12 3、涤纶人工心脏瓣膜缝合环的抗菌表面改性及机理研究(50203011)23万元,国家自然科学基金(主持),2003.1-2005.12 4、诱导抗凝血生物化表面的设计与构建(2005CB623904)215万元,国家重点基础研究发展计划(973计划)(主研),2005.10-2010.9 5、抗凝血、抗感染的表面改性新型人工心脏瓣膜(863计划,G19990964706),国家高技术研究发展计划(863计划)(主研),2006.12-2010.12 6、药物涂层/钛氧薄膜涂层冠状动脉支架技术1000万(主研),项目成果转化, 2007.1-2012.12

论文、成果、著作等

论文: 2014 (1) Zhilu Yang, Kaiqing Xiong, Pengkai Qi, Ying Yang, Qiufen Tu, Jin Wang*, Nan Huang*, Gallic Acid Tailoring Surface Functionalities of Plasma-Polymerized Allylamine-Coated 316L SS to Selectively Direct Vascular Endothelial and Smooth Muscle Cell Fate for Enhanced Endothelialization. ACS Appl. Mater. Interfaces, 2014, DOI: 10.1021/am405124z, (2) Si Chen, Xin Li, Zhilu Yang, Shuo Zhou, Rifang Luo, Manfred M. Maitz, Yuancong Zhao, Jin Wang*, Kaiqin Xiong, Nan Huang, A simple one-step modification of various materials for introducing effective multi-functional groups. Colloids and Surfaces B: Biointerfaces, 2014; 113: 125-133 (3) Si Zhong1, Rifang Luo1, Xin Wang,Linlin Tang, Jian Wu*, Jin Wang*, Runbo Huang, Hongsun, Nan Huang, Colloids and Surfaces B: Biointerfaces, 2014, in press, doi:http://dx.doi.org/10.1016/j.colsurfb.2014.01.030 2013 (4) Zhilu Yang1, Ying Yang1, Wei Yan, Qiufen Tu, Jin Wang*, Nan Huang, Construction of polyfunctional coatings assisted by gallic acid to facilitate co-immobilization of diverse biomolecules. ACS Appl. Mater. Interfaces, 2013; 5: 10495-10501 (5) Rifang Luo, Linlin Tang, Si Zhong, Zhilu Yang, Jin Wang*, Yajun Weng, Qiufen Tu, Chongxi Jiang, Nan Huang, In Vitro Investigation of Enhanced Hemocompatibility and Endothelial Cell Proliferation Associated with Quinone-Rich Polydopamine Coating. ACS Appl. Mater. Interfaces, 2013; 5: 1704?1714 (6) Rifang Luo, Linlin Tang, Jin Wang*, Yuancong Zhao, Qiufen Tu, Yajun Weng, Ru Shen, Nan Huang, Improved immobilization of biomolecules to quinone-rich polydopamine for efficient surface functionalization, Colloids and Surfaces B Biointerfaces. 2013; 106: 66-73 (7) 陈瑞,刘玉洁,李欣,王进*,孙鸿,黄楠,等离子体类聚氧乙烯薄膜的制备及性能研究. 功能材料, 2013; 44: 3255-3260 2012 (8) Zhilu Yang, Qiufen Tu, Jin Wang*, Nan Huang*, The role of heparin binding surfaces in the direction of endothelial and smooth muscle cell fate and re-endothelialization. Biomaterials, 2012; 33: 6615-6625 (9) Zhilu Yang, Qiufen Tu, Ying Zhu, Rifang Luo, Xin Li, Yichu Xie, Manfred F. Maitz, Jin Wang*, Nan Huang, Mussel-Inspired Coating of Polydopamine Directs Endothelial and Smooth Muscle Cell Fate for Re-endothelialization of Vascular Devices. Advanced Healthcare Materials, 2012; 1: 548-559 (10) Zhilu Yang1, Shuo Zhou1, Lei Lu, Xin Wang, Jin Wang*, Nan Huang*, Construction and hemocompatibility study of highly bioactive heparin-functionalized surface, Journal of Biomedical Material Research part A. 2012; 100A: 3124-3133 (11) Zhilu Yang, Jin Wu, Xin Wang, Jin Wang*, Nan Huang*, Inspired chemistry for a simple but highly effective immobilization of vascular endothelial growth factor on gallic acid-functionalized plasma polymerized film, Plasma Processes and Polymers. 2012; 9: 718-725 (12) Tingting He, Zhilu Yang, Rui Chen, Jin Wang*, Yongxiang Leng, Hong Sun, Nan Huang, Enhanced endothelialization guided by fibronectin functionalized plasma polymerized acrylic acid film, Materials Science and Engineering: C. 2012; 32: 1025-1032 (13) Zhilu Yang, Jin Wang*, Xin Li, Qiufen Tu, Hong Sun, Nan Huang, Interaction of platelets, fibrinogen and endothelial cells with plasma deposited PEO-like films, Applied Surface Science. 2012; 258: 3378-3385 2011 (14) Zhilu Yang, Qiufen Tu, Jin Wang*, Xingjiang Lei, Tingting He, Hong Sun, Nan Huang. Bioactive Plasma-Polymerized Bipolar Films of Protonated Functionality for Enhanced Endothelial Cellular Mobility. Macromolecular Bioscience. 2011;11:797-805 (15) Zhilu Yang, Xingjiang Lei, Jin Wang*, Rifang Luo, Tingting He, Hong Sun, Nan Huang. A Novel Technique Toward Bipolar Films Containing Alternating Nano–Layers of Allylamine and Acrylic Acid Plasma Polymers for Biomedical Application. Plasma Processes and Polymers. 2011;8:208-214 (16) Zhilu Yang, Jin Wang, Rifang Luo, Tingting He, Si Chen, Xingjiang Lei, Hong Sun, Nan Huang. Improved Hemocompatibility Guided by Pulsed Plasma Tailoring the Surface Amino Functionalities of TiO2 Coating for Covalent Immobilization of Heparin. Plasma Processes and Polymers. 2011;8:850-858 (17) 吴雷刚,吴婧,侯瑞霞,王进*,黄楠. 他克莫司-聚三亚甲基碳酸酯药物洗脱支架涂层研究.功能材料. 2011; 42(11): 1954-1957 (18) 俞洪飞,赵元聪,王进*. 磷酸胆碱表面改性涤纶材料及抗凝血性研究. 功能材料. 2011; 42(7): 1265-1268 2010 (19) Zhilu Yang, Jin Wang, Rifang Luo, Manfred F. Maitz, Fengjuan Jing, Hong Sun, Nan Huang. The covalent immobilization of heparin to pulsed plasma polymeric allylamine films on 316L stainless steel and the resulting effects on hemocompatibility. Biomaterials. 2010;31:2072-2083 (20) Xiaona Wang, Jin Wang, Zhilu Yang, Yongxiang Leng, Hong Sun, Nan Huang. Structural characterization and mechanical properties of functionalized pulsed-plasma polymerized allylamine film. Surface and Coatings Technology, 2010; 204(18-19): 3047-3052. (21) Xiaoqing Xue, Jin Wang*, Ying Zhu, Qiufen Tu, Nan Huang. Biocompatibility of pure titanium modified by human endothelial cell-derived extracellular matrix. Applied Surface Science, 2010; 256: 3866-3873 (22) Ruixia Hou, Leigang Wu, Jin Wang*, Nan Huang. Investigation on biological properties of tacrolimus-loaded poly(1,3-trimethylene carbonate) in vitro. Applied Surface Science, 2010; 256: 5000-5005 2004-2009 (23) Zhilu Yang, Xiaona Wang, Jin Wang*, Ye Yao, Hong Sun, Nan Huang. Pulsed-Plasma Polymeric Allylamine Thin Films. Plasma Processes and Polymers. 2009;6:498-505 (24) 左文瑾,王进,杨志禄,孙鸿,黄楠,聚乙烯吡咯烷酮等离子体接枝改性聚丙烯的亲水性及抗凝血性研究. 功能材料. 2009; 40: 667-669, 673 (25) Ren Jingrun, Wang Jin*, Sun Hong, Huang Nan. Surface modification of polyethylene terephthalate with albumin and gelatin for improvement of anticoagulation and endothelialization. Applied Surface Science, 2008; 255: 263-266 (26) 杨志禄,王进*,孙鸿,陈俊英,黄楠. 等离子体聚合沉积聚烯丙胺薄膜改性聚酯及体外血小板黏附研究. 功能材料. 2008; 39(9): 1559-1561, 1566 (27) 任玲,王进*,唐家驹,潘长江,黄楠. 含姜黄素的(丙交酯-乙交酯)共聚物薄膜对血管平滑肌细胞增殖的影响. 生物医学工程学杂志. 2008; 25( 4): 874-877 (28) 王海波,王进*,王晓娜,孙鸿,黄楠,等离子体聚合薄膜改性医用不锈钢及内皮细胞黏附行为研究.功能材料. 2008; 39(7): 1193-1196 (29) 唐家驹,王进*,潘长江,任玲,黄楠.姜黄素/聚乳酸—乙醇酸共聚物复合薄膜的制备及抗凝血研究. 生物医学工程学杂志. 2008; 25(1): 113-116 (30) 闫峰,王进,杨志禄,张钊,孙鸿,黄楠. 白蛋白固定等离子体聚烯丙胺薄膜及体外血小板粘附行为. 生物医学工程研究. 2008; 27(4): 268-271 (31) J. X. Li, J. Wang*, L. R. Shen, Z. J. Xu, P. Li, G. J. Wan, N. Huang. The influence of polyethylene terephthalate surfaces modified by silver ion implantation on bacterial adhesion behavior. Surface & Coatings Technology, 2007; 201: 8155-8159 (32) 侯瑞霞,翁亚军,王进*,王志浩,冷永祥,黄楠. Ti-O-N表面肝素分子的共价固定及抗凝血性研究.无机材料学报, 2007; 22(5): 996-1000 (33) Jin Wang, Jianxin Li, Ling Ren, Ansha Zhao, Peng Li, Yongxiang Leng, Hong Sun, Nan Huang. Antibacterial activity of silver surface modified polyethylene terephthalate by filtered cathodic vacuum arc method, Surf. Coat. Tech.. 2007; 201: 6893-6896 (34) Wang Jin, Li Jianxin, Shen Liru, Ren Ling, Xu Zejin, Zhao Ansha, Leng Yongxiang, Huang Nan. The biomedical properties of polyethylene terephthalate surface modified by silver ion implantation, Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms. 2007; 257: 141-1456 (35) J. Wang, J.Y. Chen, P. Yang, Y.X. Lenga, G.J. Wan, H. Sun, A.S. Zhao, N. Huang, P.K. Chu. In vitro platelet adhesion and activation of polyethylene terephthalate modified by acetylene plasma immersion ion implantation and deposition. Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms. 2007; 242:12-14 (36) Wang Jin, Tang Jiaju, Ren ling, Pan Changjiang, Huang Nan, Effect of rapamycin/curcumin co-loaded poly(Lactide-Co-Glycolide) films on blood compatibility and vascular smooth muscle cell proliferation. Key Engineering Materials. 2007; 342-343: 317-320 (37) Tang Jiaju, Wang Jin*, Pan Changjiang, Weng Yajun, Huang Nan, Anticoagulation and drug release behavior of curcumin-loaded PLGA films. Key Engineering Materials. 2007; 342-343: 481-484 (38) L. Ren, J. Wang*, J.J. Tang, Ch.J. Pang, M. Maitz, N. Huang, Biological evaluation of sirolimus-loaded PLGA films. Key Engineering Materials. 2007; 342-343:837-840 (39) Jianxin Li, Jin Wang,* Peng Li, Yajun Weng, Ling Ren, Xueling Fei,Hong Sun, Nan Huang, Ozone-induced immobilization of chitosan and heparin on polyethylene terephthalate films to improve antithrombogenic properties. Key Engineering Materials. 2007; 342-343:809-812 (40) J. Wang, J.Y. Chen, P. Yang, Y.X. Lenga, G.J. Wan, H. Sun, A.S. Zhao, N. Huang, P.K. Chu. In vitro platelet adhesion and activation of polyethylene terephthalate modified by acetylene plasma immersion ion implantation and deposition. Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms. 2006; 242:12-14 (41) 王进,潘长江,李鹏,冷永祥,陈俊英,万国江,杨苹,孙鸿,黄楠. 医用涤纶材料表面类金刚石涂层的表面自由能参数对细菌粘附的影响. 生物医学工程学杂志. 2006; 23(2): 342-345 (42) 李建新,王进*,沈丽如,许泽金,陈燕,李鹏,黄楠. 银离子注入表面改性涤纶材料的抗菌性能研究. 真空科学与技术学报. 2006; 26(5): 408-411 (43) 唐家驹,潘长江,洪玮,王进*,黄楠. 大黄素/聚乳酸物复合薄膜的制备及抗凝血研究. 功能材料. 2006; 37(8): 1312-1313, 1317 (44) Wang, J., Pan C.J., Huang, N., Sun, H., Yang, P., Leng, Y.X., Chen, J.Y., Wan, G.J., Chu, P.K., Surface characterization and blood compatibility of poly(ethylene terephthalate) modified by plasma surface grafting.Surface & Coatings Technology.2005; 196: 307-11 (45) Wang J., Li P., Sun H., Yang P., Leng Y. X., Chen J.Y., Huang N.. Blood Compatibility of Chitosan Immobilized on Poly(Ethylene Terephthalate) Surface Modified by Plasma and Ultraviolet Grafting. Key Engineering Materials. 2005; 288-289: 327-330 (46) 王进,Kwok S.C.H.,陈俊英,杨萍,黄楠,Chu P. K..磷掺杂类金刚石薄膜的制备与性能研究.真空科学与技术学报. 2005; 25(2):123-126 (47) Wang J., Huan, N., Yang P., Leng Y.X., Sun H., Liu Z.Y., Chu, P.K.. The effects of amorphous carbon films deposited on polyethylene terephthalate on bacterial adhesion. Biomaterials. 2004; 25: 3163-70 (48) Wang J., Huang, N., Pan, C.J., Kwok, S.C.H., Yang, P., Leng, Y.X., Chen, J.Y., Sun H., Wan G.J., Liu Z.Y., Chu P.K.. Bacterial repellence from polyethylene terephthalate surface modified by acetylene plasma immersion ion implantation-deposition. Surface & Coatings Technology. 2004; 186: 299-304 (49) Wang J., Pan C.J., Kwok S.C.H., Yang P., Chen J.Y., Wan G.J., Huang N., Chu P.K.. Characteristics and anticoagulation behavior of polyethylene terephthalate modified by C2H2 plasma immersion ion implantation-deposition. Journal of Vacuum Science & Technology A (Vacuum, Surfaces, and Films). 2004; 22: 170-5 专著 黄楠,王进译《生物材料科学:医用材料导论》(顾中伟,刘伟、俞耀庭等译校)第7章第3节--- “心血管医疗器械”,科学出版社,2011.06

专利、著作版权等

授权发明专利 1. 王进,杨志禄,黄楠,冷永祥,赵元聪,一种具有高生物功能性的肝素化界面材料制备方法,中国发明专利ZL201110195704.5,授权时间2013年7月31日 2. 王进,杨志禄,冷永祥,孙鸿,黄楠,基于类聚乙二醇的可回收下腔静脉滤器表面膜制备方法,中国发明专利ZL201110277736.X,授权时间2013年6月12日 3. 王进,黄楠,杨苹,孙鸿,冷永祥,陈俊英,万国江,赵安莎,游天雪,吴熹,一种具有抗菌功能的人工心脏瓣膜缝合环涤纶材料,中国发明专利ZL20081004605ࣺᯬ
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