主持国家自然科学基金青年基金、重庆市自然科学基金、重庆市教委雏鹰计划研究项目、中央高校基本科研业务费等多项课题。主研国家自然科学基金面上项目、重庆市自然科学基金重点项目、重庆市百人计划启动基金、生物大分子国家重点实验室开放基金、中央高校科研业务费创新团队项目等多项课题

代表性论文： 1. Wang, P.; He, H.W.; Cai, R.; Tao, G.; Yang, M.R.; Zuo, H.; Umar, A.; Wang, Y.J.* Cross- linking of dialdehyde carboxymethyl cellulose with silk sericin to reinforce sericin film for potential biomedical application. Carbohydrate Polymers. 2019, 212: 403-411. 2. Tao, G.; Wang, Y.J.; Cai R.; Chang H.P.; Song K.; Zuo H.; Zhao P.; Xia Q.Y.; He H.W. Design and performance of sericin/poly (vinyl alcohol) hydrogel as a drug delivery carrier for potential wound dressing application. Materials Science & Engineering C, 2019, 101: 341-351. 3. Liu, L.N.; Wang, Y.J.; Li, Y.; Guo, P.C.; Liu, C.; Li, Zhi, Q.; Wang, F.; Zhao, P.; Xia, Q.Y; He, H.W. Insights into the repression of fibroin modulator binding protein-1 on the transcription of fibroin H-chain during molting in Bombyx mori. Insect Biochem Mol Biol. 2019, 104: 39-49. 4. Wang, Y.J.; Cai, R.; Tao, G.; Wang, P.; Zuo, H.; Zhao, P.; Umar, A.; He, H.W. A Novel AgNPs/Sericin/Agar Film with Enhanced Mechanical Property and Antibacterial Capability. Molecules. 2018, 23(7): 1821-1835. 5. Yang, M.R.; Wang, Y.J.; Tao, G.; Cai, R.; Wang, P.; Liu, L.Y.; Ai, L.S.; Zuo, H.; Zhao, P.; Umar, A.; Mao, C.B.; He, H.W. Fabrication of Sericin/Agrose Gel Loaded Lysozyme and Its Potential in Wound Dressing Application. Nanomaterials. 2018, 8(4): 235-249. 6. Li, Y. ; Wang, Y.J.; Song, K.; Liu, L.N.; Cai, R.; Tao, G.; Zhao, P.; Zhou, H.M.; He, H.W. A rapid and sensitive colorimetric assay for the determination of adenosine kinase activity. Biochemical and biophysical research communications. 2018, 502(2): 250-254. 7. Liu, L.Y., Cai, R., Wang, Y.J.; Tao, G.; Ai, L.S.; Wang, P.; Yang, M.R.; Zuo, H.; Zhao, P.; Shen, H.; Umar, A.; He, H.W. Preparation and characterization of AgNPs in situ synthesis on polyelectrolyte membrane coated sericin/agar film for antimicrobial applications. Materials. 2018, 11(7): 1205-1219. 8. Yang, M.R.; Wang, Y.J.; Cai, R.; Tao, G.; Chang, H.P.; Ding, C.X.; Zuo, H.; Shen, H.; Zhao, P.; He, H.W. Preparation and Characterization of Silk Sericin/ Glycerol Films Coated with Silver Nanoparticles for Antibacterial Application. Science of Advanced Materials. 2018, 10(6): 761-768. 9. Liu, L.Y., Cai, R.; Wang, Y.J.; Tao, G.; Ai, L.S.; Wang, P.; Yang, M.R.; Zuo, H.; Zhao, P.; He, H.W. Polydopamine-Assisted Silver Nanoparticle Self-Assembly on Sericin/Agar Film for Potential Wound Dressing Application. International journal of molecular sciences. 2018, 19(10): 2875-2891. 10. Cai, R.; Tao, G.; He, H.W.; Guo, P.C.; Yang, M.R., Ding, C.X.; Zuo, H.; Wang, L.Y.; Zhao, P; Wang, Y.J*. In Situ Synthesis of Silver Nanoparticles on the Polyelectrolyte-Coated Sericin/ PVA Film for Enhanced Antibacterial Application. Materials. 2017, 10(8): 967-981. 11. He, H.W.; Tao, G.; Wang, Y.J.; Cai, R.; Guo, P.C.; Chen, L.Q.; Zuo, H.; Zhao, P.; Xia, Q.Y. In situ green synthesis and characterization of sericin-silver nanoparticle composite with effective antibacterial activity and good biocompatibility. Materials Science and Engineering C. 2017, 80: 509-516. 12. Tao, G.; Cai, R.; Wang, Y.J.; Song, K.; Guo, P.C.; Zhao, P.; Zuo, H.; He, H.W. Biosynthesis and Characterization of AgNPs–Silk/PVA Film for Potential Packaging Application. Materials. 2017, 10(6): 667-679. 13. He, H.W., Cai, R.; Wang, Y.J.; Tao, G.; Guo, P.C.; Zuo, H.; Chen, L.Q.; Liu, X.Y.; Zhao, P.; Xia, Q.Y. Preparation and characterization of silk sericin/PVA blend film with silver nanoparticles for wound healing application. International Journal of Biomacromolecules. 2017, 104(Pt A): 457-464. 14. Cai, R.; Tao, G.; He, H.W.; Song, K.; Zuo, H.; Jiang W.C.; Wang, Y.J.* One-Step Synthesis of Silver Nanoparticles on Polydopamine-Coated Sericin/ Polyvinyl Alcohol Composite Films for Potential Antimicrobial Applications. Molecules. 2017, 22(5): 721-734. 15. Liu, L.N.; Wang, Y.J.; Li, Y.; Lin, Y.; Hou, Y.; Zhang, Y.; Wei, S.G.; Zhao, P.; Zhao, P.; He, H.W. LBD1 of Vitellogenin Receptor Specifically Binds to the Female-Specific Storage Protein SP1 via LBR1 and LBR3. PLoS ONE. 2016, 11(9): e0162317. 16. Tao, G.; Wang, Y.J.; Liu, L.N.; Chang, H.P.; Zhao, P.; He, H.W. Preparation and characterization of silver nanoparticles composited on polyelectrolyte film coated sericin gel for enhanced antibacterial application. Science of Advanced Materials. 2016, 8(8): 1547-1552. 17. Liu, L.N.; Li, Y.; Wang, Y.J.; Zhao, P.; Wei, S.G.; Li, Z.Z.; Chang, H.P.; He, H.W. Biochemical characterization and functional analysis of the POU transcription factor POU-M2 of Bombyx mori. International Journal of Biological Macromolecules. 2016, 86: 701-708. 18. Tao, G.; Liu, L.N.; Wang, Y.J.; Chang, H.P.; Zhao, P.; Zuo, H.; He,H.W. Characterization of silver nanoparticle in situ synthesis on porous sericin gel for antibacterial application. Journal of Nanomaterials. 2016, 2016 (10): 1-8. 19. Wang, Y.J.; He, H.W.; Liu, L.N.; Gao, C.Y.; Xu, S.; Zhao, P.; Xia, Q.Y. Inactivation and Unfolding of Protein Tyrosine Phosphatase from Thermus thermophilus HB27 during Urea and Guanidine Hydrochloride Denaturation. PLoS ONE. 2014, 9(9): e107932. 20. Wang, Y.J.; He, H.W.; Li, S. Effect of Ficoll 70 on Thermal Stability and Structure of Creatine Kinase. Biochemistry(Moscow). 2010, 75(5): 648-654. 21. Wang, Y.J.; Meng, F.G.; Zhang, Y.M. Expression, purification and characteriza tion of recombinant protein tyrosine phosphatase from Thermus thermophilus HB27. Acta Bioch Biophy Sin. 2009, 41(8): 689-698. 22. Lü, Z.R.; Wang, Y.J.; Lee, D.Y.; Park, Y.D.; Zou, H.C.; Zou, F. The effect of Zn2+ on human brain creatine kinase: unfolding and aggregation studies. J Biomol Struct Dyn. 2009, 26(5): 567-574. 23. Zou, H.C.; Lü, Z.R.; Wang, Y.J.; Zhang, Y.M.; Zou, F.; Park, Y.D. Effect of cysteine modification on creatine kinase aggregation. Appl Biochem Biotechnol. 2009, 152(1): 15-28. 24. Zhang, Y.M.; Wang, Y.J.; Yu, R.L.; Zhang, S.; Wu, Z.B. Effect of heavy metals Cd2+, Pb2+ and Zn2+ on DNA damage of loach misgurnus anguillicandatu. Front. Biol. China. 2008, 3(1): 50-54. 25. Zou, H.C.; Yu,Z.H.; Wang, Y.J.; Yang, J.M.; Zhou, H.M.; Meng, F.G.; Park, Y.D. Monomeric creatine kinase aggregation and sodium dodecyl sulfate-cyclodextrin assisted refolding. J Biomol Struct Dyn. 2007, 24(4): 359-368. 26. Huang, D.J.; Zhang, Y.M.; Wang, Y.J.; Xie, Z.Y.; Ji, W.H. Assessment of the genotoxicity in toad Bufo raddei exposed to petrochemical contaminants in Lanzhou Region, China. Mutat Res-Gen Tox En. 2007, 629(2): 81-88. 27. Han, H.Y.; Zou, H.C.; Jeon, J.Y.; Wang, Y.J.; Xu, W.A.; Yang, J.M.; Park, Y.D. The inhibition kinetics and thermodynamic changes of tyrosinase via the zinc ion. Biochim Biophys Acta. 2007, 1774(7): 822-827.