教育背景
1981-1985,西南农业大学本科生。
1985-1996,四川省农科院蚕研所工作。
1991-1996,西南农业大学博士生。
工作经历
1997-2001,日本九州大学博士后、特别研究员。
2000– ,西南大学教授、博导
2002– ,农业部蚕桑功能基因组与生物技术重点开放实验室副主任
2005–2007,西南大学蚕学与生物技术学院院长
2005–2012 ,教育部家蚕基因组学重点实验室副主任
2006– ,西南大学蚕学与系统生物学研究所副所长
2007–2016,西南大学生物技术学院院长
2011-2018 ,家蚕基因组生物学国家重点实验室主任
项目课题经历
主持973、863等项目30余个
论文、成果、著作等
代表性论文:
1: Xia Q, Zhou Z, Lu C, Cheng D, Dai F, Li B, Zhao P, Zha X, Cheng T, Chai C, Pan G, Xu J, Liu C, Lin Y, Qian J, Hou Y, Wu Z, Li G, Pan M, Li C, Shen Y, Lan X, Yuan L, Li T, Xu H, Yang G, Wan Y, Zhu Y, Yu M, Shen W, Wu D, Xiang Z, Yu J, Wang J, Li R, Shi J, Li H, Li G, Su J, Wang X, Li G, Zhang Z, Wu Q, Li J, Zhang Q, Wei N, Xu J, Sun H, Dong L, Liu D, Zhao S, Zhao X, Meng Q, Lan F, Huang X, Li Y, Fang L, Li C, Li D, Sun Y, Zhang Z, Yang Z, Huang Y, Xi Y, Qi Q, He D, Huang H, Zhang X, Wang Z, Li W, Cao Y, Yu Y, Yu H, Li J, Ye J, Chen H, Zhou Y, Liu B, Wang J, Ye J, Ji H, Li S, Ni P, Zhang J, Zhang Y, Zheng H, Mao B, Wang W, Ye C, Li S, Wang J, Wong GK, Yang H; Biology Analysis Group. A draft sequence for the genome of the domesticated silkworm (Bombyx mori). Science. 2004, 306(5703):1937-40.
2: Xia Q, Guo Y, Zhang Z, Li D, Xuan Z, Li Z, Dai F, Li Y, Cheng D, Li R, Cheng T, Jiang T, Becquet C, Xu X, Liu C, Zha X, Fan W, Lin Y, Shen Y, Jiang L, Jensen J, Hellmann I, Tang S, Zhao P, Xu H, Yu C, Zhang G, Li J, Cao J, Liu S, He N, Zhou Y, Liu H, Zhao J, Ye C, Du Z, Pan G, Zhao A, Shao H, Zeng W, Wu P, Li C, Pan M, Li J, Yin X, Li D, Wang J, Zheng H, Wang W, Zhang X, Li S, Yang H, Lu C, Nielsen R, Zhou Z, Wang J, Xiang Z*, Wang J*. Complete resequencing of 40 genomes reveals domestication events and genes in silkworm (Bombyx). Science. 2009, 326(5951):433-6.
3: Xia Q, Cheng D, Duan J, Wang G, Cheng T, Zha X, Liu C, Zhao P, Dai F, Zhang Z, He N, Zhang L, Xiang Z. Microarray-based gene expression profiles in multiple tissues of the domesticated silkworm, Bombyx mori. Genome Biol. 2007,8(8):R162.
4: Xia QY, Fujii H, Kusakabe T, Banno Y. Identification of three annexin IX isoforms generated by alternative splicing of the carboxyl-terminal exon in silkworm, Bombyx mori. Insect Biochem Mol Biol. 2001,32(1):9-14.
5: Liu C, Yamamoto K, Cheng TC, Kadono-Okuda K, Narukawa J, Liu SP, Han Y, Futahashi R, Kidokoro K, Noda H, Kobayashi I, Tamura T, Ohnuma A, Banno Y, Dai FY, Xiang ZH, Goldsmith MR, Mita K, Xia QY*. Repression of tyrosine hydroxylase is responsible for the sex-linked chocolate mutation of the silkworm, Bombyx mori. Proc Natl Acad Sci U S A. 2010, 107(29):12980-5.
6: Duan J, Li R, Cheng D, Fan W, Zha X, Cheng T, Wu Y, Wang J, Mita K, Xiang Z, Xia Q*. SilkDB v2.0: a platform for silkworm (Bombyx mori ) genome biology. Nucleic Acids Res. 2010,38(Database issue):D453-6.
7: Zhao P, Dong Z, Duan J, Wang G, Wang L, Li Y, Xiang Z, Xia Q*. Genome-wide identification and immune response analysis of serine protease inhibitor genes in the silkworm, Bombyx mori. PLoS One. 2012;7(2):e31168.
8: Xie X, Cheng T, Wang G, Duan J, Niu W, Xia Q*. Genome-wide analysis of the ATP-binding cassette (ABC) transporter gene family in the silkworm, Bombyx mori. Mol Biol Rep. 2012 Feb 5.
9: Yang W, Cheng T, Ye M, Deng X, Yi H, Huang Y, Tan X, Han D, Wang B, Xiang Z, Cao Y*, Xia Q*. Functional divergence among silkworm antimicrobial peptide paralogs by the activities of recombinant proteins and the induced expression profiles. PLoS One. 2011,29;6(3):e18109.
10: Ma L, Xu H, Zhu J, Ma S, Liu Y, Jiang RJ, Xia Q*, Li S*. Ras1(CA) overexpression in the posterior silk gland improves silk yield. Cell Res. 2011, 21(6):934-43.
11: Wei L, Cheng D, Li D, Meng M, Peng L, Tang L, Pan M, Xiang Z, Xia Q*, Lu C*. Identification and characterization of Sox genes in the silkworm, Bombyx mori. Mol Biol Rep. 2011, 38(5):3573-84.
12: Zhao P, Wang GH, Dong ZM, Duan J, Xu PZ, Cheng TC, Xiang ZH, Xia QY*. Genome-wide identification and expression analysis of serine proteases and homologs in the silkworm Bombyx mori. BMC Genomics. 2010,11:405.
13: Xiang H, Zhu J, Chen Q, Dai F, Li X, Li M, Zhang H, Zhang G, Li D, Dong Y, Zhao L, Lin Y, Cheng D, Yu J, Sun J, Zhou X, Ma K, He Y, Zhao Y, Guo S, Ye M, Guo G, Li Y, Li R, Zhang X, Ma L, Kristiansen K, Guo Q, Jiang J, Beck S, Xia Q*, Wang W*, Wang J*. Single base-resolution methylome of the silkworm reveals a sparse epigenomic map. Nat Biotechnol. 2010, 28(5):516-20.
14: Li D, Guo Y, Shao H, Tellier LC, Wang J, Xiang Z, Xia Q*. Genetic diversity, molecular phylogeny and selection evidence of the silkworm mitochondria implicated by complete resequencing of 41 genomes. BMC Evol Biol. 2010, 10:81.
15: Liu S, Li D, Li Q, Zhao P, Xiang Z, Xia Q*. MicroRNAs of Bombyx mori identified by Solexa sequencing. BMC Genomics. 2010,11:148.
16: Liu S, Gao S, Zhang D, Yin J, Xiang Z, Xia Q*. MicroRNAs show diverse and dynamic expression patterns in multiple tissues of Bombyx mori. BMC Genomics. 2010,11:85.
17: Huang L, Cheng T, Xu P, Cheng D, Fang T, Xia Q*. A genome-wide survey for host response of silkworm, Bombyx mori during pathogen Bacillus bombyseptieus infection. PLoS One. 2009,4(12):e8098.
18: Gong DP, Zhang HJ, Zhao P, Xia QY*, Xiang ZH. The odorant binding protein gene family from the genome of silkworm, Bombyx mori. BMC Genomics. 2009,10:332.
19: Huang L, Cheng T, Xu P, Duan J, Fang T, Xia Q*. Immunoglobulin superfamily is conserved but evolved rapidly and is active in the silkworm, Bombyx mori. Insect Mol Biol. 2009,18(4):517-30.
20: Zhang Y*, Xia Q*, Xu J, Chen J, Nie Z, Wang D, Zhang W, Chen J, Zheng Q, Chen Q, Kong L, Ren X, Wang J, Lv Z, Yu W, Jiang C, Liu L, Sheng Q, Jin Y, Wu X. Aligning the proteome and genome of the silkworm, Bombyx mori. Funct Integr Genomics. 2009, 9(4):447-54.
21: Liu Z, Xia L, Wu Y, Xia Q, Chen J, Roux KH. Identification and
characterization of an arginine kinase as a major allergen from silkworm (Bombyx mori) larvae. Int Arch Allergy Immunol. 2009,150(1):8-14.
22: Couble P, Mita K, Xia Q. Editorial: Silkworm genome. Insect Biochem Mol Biol. 2008, 38(12):1035.
23: Zha X, Xia Q*, Duan J, Wang C, He N, Xiang Z. Dosage analysis of Z chromosome genes using microarray in silkworm, Bombyx mori. Insect Biochem Mol Biol. 2009, 39(5-6):315-21.
24: Cheng D, Xia Q*, Duan J, Wei L, Huang C, Li Z, Wang G, Xiang Z. Nuclear receptors in Bombyx mori: insights into genomic structure and developmental expression. Insect Biochem Mol Biol. 2008, 38(12):1130-7.
25: Duan J, Xia Q*, Cheng D, Zha X, Zhao P, Xiang Z. Species-specific expansion of C2H2 zinc-finger genes and their expression profiles in silkworm, Bombyx mori. Insect Biochem Mol Biol. 2008 ,38(12):1121-9.
26: Liu S, Xia Q*, Zhao P, Cheng T, Hong K, Xiang Z. Characterization and expression patterns of let-7 microRNA in the silkworm (Bombyx mori). BMC Dev Biol. 2007,7:88.
27: Zhao P, Xia Q*, Li J, Fujii H, Banno Y, Xiang Z. Purification, characterization and cloning of a chymotrypsin inhibitor (CI-9) from the hemolymph of the silkworm, Bombyx mori. Protein J. 2007, 26(5):349-57.
28: Cheng TC, Zhang YL, Liu C, Xu PZ, Gao ZH, Xia QY*, Xiang ZH. Identification and analysis of Toll-related genes in the domesticated silkworm, Bombyx mori. Dev Comp Immunol. 2008,32(5):464-75.
29: Hou Y, Xia Q*, Zhao P, Zou Y, Liu H, Guan J, Gong J, Xiang Z. Studies on middle and posterior silk glands of silkworm (Bombyx mori) using two-dimensional electrophoresis and mass spectrometry. Insect Biochem Mol Biol. 2007, 37(5):486-96.
30: Gong J, Hou Y, Zha XF, Lu C, Zhu Y, Xia QY*. Molecular cloning and characterization of Bombyx mori sterol carrier protein x/sterol carrier protein 2 (SCPx/SCP2) gene. DNA Seq. 2006, 17(5):326-33.
31: Gong DP, Zhang HJ, Zhao P, Lin Y, Xia QY*, Xiang ZH. Identification and expression pattern of the chemosensory protein gene family in the silkworm, Bombyx mori. Insect Biochem Mol Biol. 2007, 37(3):266-77.
32: Xu HF, Xia QY*, Liu C, Cheng TC, Zhao P, Duan J, Zha XF, Liu SP. Identification and characterization of piggyBac-like elements in the genome of domesticated silkworm, Bombyx mori. Mol Genet Genomics. 2006, 276(1):31-40.
33: Cheng T, Zhao P, Liu C, Xu P, Gao Z, Xia Q*, Xiang Z. Structures, regulatory regions, and inductive expression patterns of antimicrobial peptide genes in the silkworm Bombyx mori. Genomics. 2006, 87(3):356-65.
34: Cheng DJ, Xia QY*, Zhao P, Wang ZL, Xu HF, Li GR, Lu C, Xiang ZH. EST-based profiling and comparison of gene expression in the silkworm fat body during metamorphosis. Arch Insect Biochem Physiol. 2006, 61(1):10-23.
35: Li B, Xia Q*, Lu C*, Zhou Z, Xiang Z. Analysis of cytochrome P450 genes in silkworm genome (Bombyx mori). Sci China C Life Sci. 2005, 48(4):414-8.
36: Zha XF, Xia QY*, Zhao P, Li J, Duan J, Wang ZL, Qian JF, Xiang ZH. Detection and analysis of alternative splicing in the silkworm by aligning expressed sequence tags with the genomic sequence. Insect Mol Biol. 2005, 14(2):113-9.
37: Wang J, Xia Q, He X, Dai M, Ruan J, Chen J, Yu G, Yuan H, Hu Y, Li R, Feng T, Ye C, Lu C, Wang J, Li S, Wong GK, Yang H, Wang J, Xiang Z, Zhou Z, Yu J. SilkDB: a knowledgebase for silkworm biology and genomics. Nucleic Acids Res. 2005, 1;33(Database issue):D399-402.
38: Cheng TC, Xia QY*, Liu C, Zhao P, Zha XF, Xu HF, Xiang ZH. [Three Bombyx mori genes, chi, gluE and fruA, encode proteins homologous to microorganism and primary analysis of horizontal gene transfer]. Yi Chuan Xue Bao. 2004, 31(10):1082-8.
39: Cheng TC, Xia QY*, Qian JF, Liu C, Lin Y, Zha XF, Xiang ZH. Mining single nucleotide polymorphisms from EST data of silkworm, Bombyx mori, inbred strain Dazao. Insect Biochem Mol Biol. 2004, 34(6):523-30.
专利、著作版权等
申请基因专利36余项、出版专著:
夏庆友, 向仲怀 主编. 《家蚕基因组计划2000-2007》,西南师范大学出版社, 2008.6
夏庆友,向仲怀 主编. 《家蚕基因组计划2008-2009》(上、下册),西南师范大学出版社,2010.12
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