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周泽扬

领域:生物产业 学校:西南大学职称:教授

家蚕微孢子虫的功能基因组学研究、蚕桑病原微生物检测与防控、微生物资源及次生代谢研究...

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教育背景

1978-1982,西南农业大学,本科 1987-1990,日本信州大学,硕士 1990-1993,日本大阪大学,博士

工作经历

1996-2005,西南农业大学,教授、博士生导师 2005-至今,西南大学,教授、博士生导师

项目课题经历

主持开展了蚕桑病原微生物抗病、检测,功能基因组学、寄生虫与宿主互作关系以及资源微生物开发利用等研究。近年来先后主持“863”项目、 “973”项目子课题、国家转基因植物专项、国家自然科学基金重点项目等20余项重大课题

论文、成果、著作等

代表性论文/论著: 周泽扬,潘国庆,许金山,李田等,家蚕微孢子虫基因组学,2014,科学出版社 [1]. Han B , Zhou K, Li Z, Sun B, Ni Q, Meng X, Pan G, Li C, Long M, Li T, Zhou C, Li W, Zhou Z. Characterization of the First Fungal Glycosyl Hydrolase Family 19 Chitinase (NbchiA) from Nosema bombycis (Nb). J Eukaryot Microbiol. 2016, 63(1):37-45. [2]. Pan Q, Wang L, Dang X, Ma Z, Zhang X, Chen S, Zhou Z, Xu J. Bacterium-Expressed dsRNA Downregulates Microsporidia Nosema bombycis Gene Expression. J Eukaryot Microbiol, 2016 Jul. doi: 10.1111/jeu. 12346. [Epub ahead of print] [3]. Li Y, Tao M, Ma F, Pan G, Zhou Z, Wu Z. A monoclonal antibody that tracks endospore formation in the microsporidium Nosema bombycis. PLoS One. 2015, 10(3): e0121884. [4]. Xie J, Strobel GA, Feng T, Ren H, Mends MT, Zhou Z, Geary B. An endophytic Coniochaeta velutina producing broad spectrum antimycotics. J Microbiol. 2015, 53(6): 390–397. [5]. Zhao W, Hao Y, Wang L, Zhou Z, Li Z. Development of a strategy for the identification of surface proteins in the pathogenic microsporidian Nosema bombycis. Parasitology. 2015, 142(07): 1-14. [6]. He Q, Ma Z, Dang X, Xu J, Zhou Z. Identification, Diversity and Evolution of MITEs in the Genomes of Microsporidian Nosema Parasites. PLoS One. 2015, 10(4): e0123170. [7]. Yang D, Pan G, Dang X, Shi Y, Li C, Peng P, Luo B, Bian M, Song Y, Ma C, Chen J, Ma Z, Geng L, Li Z, Tian R, Wei C, Zhou Z. Interaction and assembly of two novel proteins in the spore wall of the microsporidian species Nosema bombycis and their roles in adherence to and infection of host cells. Infect Immun. 2015, 83(4): 1715-1731. [8]. Wang Ling, He Chengmin, Dang Xiaoqun, Xu Jinshan, Zhou Zeyang. Identification,Evolutionary and Transcriptional Activity Analyses of a Dicer-like Gene in Microsporidium Nosema bombycis. Science of Sericulture. 2015,41(1): 0064-0071. (In Chinese) [9]. ZHANG Suzhen, XU Jinshan, MA Zhengang, ZHOU Zeyang. stablishment and Application of a Method Suitable for Extracting Midgut Total Proteins from Honeybe Apis melifera ligustica. J Chongqing Normal University (Natural Science). 2015, 32(4): 49-53. (In Chinese) [10]. Liu T, Xu J, Luo B, Chen J, Li Z, Li T, Pan G, Li X, Zhou Z. Nosema sp. PM-1, a new isolate of microsporidian from infected Papilio machaon Linnaeus, based on ultrastructure and molecular identification. Acta Parasitol. 2015, 60(2): 330-336. [11]. Wang Y, Dang X, Luo B, Li C, Long M, Li T, Li Z, Pan G, Zhou Z. Characterization of a novel otubain-like protease with deubiquitination activity from Nosema bombycis (Microsporidia). Parasitol Res. 2015. [Epub ahead of print] [12]. He Q, Liu SL, Ma ZG, Zhang YY, Vossbrinck CR, Xu JS, Zhou ZY. Comparative genomics of three geographical strains reveals genetic diversity in Antheraea pernyi nucleopolyhedroviruses. Acta Entomol Sinica. 2015, 58(5):535-54. [13]. Wang Y, Dang X, Ma Q, Liu F, Pan G, Li T, Zhou Z.Characterization of a novel spore wall protein NbSWP16 with proline-rich tandem repeats from Nosema bombycis (microsporidia). Parasitology. 2014, 3:1-9. [PubMed] [14]. Xiang H, Zhang R, De Koeyer D, Pan G, Li T, Liu T, Zhou Z. New evidence on the relationship between Microsporidia and Fungi: a genome-wide analysis by DarkHorse software. Can J Microbiol. 2014 Jul 14:1-12. [PubMed] [15]. Bo Luo, Handeng Liu, Guoqing Pan, Tian Li, Zeng Li, Xiaoqun Dang, Tie Liu, Zeyang Zhou. Morphological and molecular studies of Vairimorpha necatrix BM, a new strain of the microsporidium V. necatrix (microsporidia, burenellidae) recorded in the silkworm, Bombyx mori. Exp Parasitol. 2014, pii: S0014-4894(14)00115-5. doi: 10.1016/j.exppara.2014.05.001. [PubMed] [16]. LIU Tie, XU Jin⁃Shan, LI Tian, PAN Guo⁃Qing, HE Qiang, LI Xue⁃Ya, ZHOU Ze⁃Yang. Identification and Phylogenetic Analysis of MITE Transposons in a Microsporidia Isolate from Papilio machaon Linnaeus. Science of Sericulture. 2014, 40(1): 0052-0058. (In Chinese) [17]. Zhengang Ma, Chunfeng Li, Guoqing Pan, Zhihong Li, Bing Han, Jinshan Xu, Xiqian Lan, Jie Chen, Donglin Yang, Quanmei Chen, Qi Sang, Xiaocun Ji, Tian Li, Mengxian Long, Zeyang Zhou. Genome-wide transcriptional response of silkworm (Bombyx mori) to infection by the microsporidian Nosema bombycis. PloS ONE. 2013, 8(12): e84137. [PubMed] [18]. Chen J, Geng L, Long M, Li T, Li Z, Yang D, Ma C, Wu H, Ma Z, Li C, Pan G, Zhou Z. Identification of a novel chitin-binding spore wall protein (NbSWP12) with a BAR-2 domain from Nosema bombycis (microsporidia). Parasitology. 2013, 140(11): 1394-402. [PubMed] [19]. Yang D, Dang X, Tian R, Long M, Li C, Li T, Chen J, Li Z, Pan G, Zhou Z. Development of an approach to analyze the interaction between Nosema bombycis (microsporidia) deproteinated chitin spore coats and spore wall proteins. J Invertebr Pathol. 2013, pii:S0022-2011(13)00149-3. [PubMed] [20]. Pan G, Xu J, Li T, Zhou Z et al. Comparative genomics of parasitic silkworm microsporidia reveal an association between genome expansion and host adaptation. BMC Genomics, 2013, 14: 186. [PubMed] [21]. Dang X, Pan G, Li T, Zhou Z, et al. Characterization of a subtilisin-like protease with apical localization from microsporidian Nosema bombycis. J Invertebr Pathol, 2013, 112(2): 166-174. [PubMed] [22]. Liu H, Pan G, Dang X, Li T, Zhou Z. et al. Characterization of active ribosomal RNA harboring MITEs insertion in microsporidian Nosema bombycis genome. Parasitol Res, 2013, 112(3):1011-1020. [PubMed] [23]. GENG Li-Na, WU Hai-Jing, LIU Ting, TIAN Rui, LI Tian, PAN Guo-Qing, ZHOU Ze-Yang. Two-dimensional Electrophoresis Analysis of Nosema bombycis Spore Coat Proteins Prepared by Germination Method and Glas Beads Breaking Method. Science of Sericulture. 2013, 39(5): 0928-0934. [In Chinese] [24]. LI Zhi-Hong, MA Zhen-Gang, LI Wan-Jun, LIU Jun, HAN Bing, LI Tian, PAN Guo-Qing, LI Chun-Feng, ZHOU Ze-Yang. Analysis and Identification of the Differentially Expressed Hemolymph Proteins of Silkworm (Bombyx mori) Infected by Nosema bombycis. Science of Sericulture. 2013, 39(5): 0921-0927. [In Chinese] [25]. LUO Jie, DENG Yuan-Hong, HUANG Wei, LI Tian, YANG Qiong, YIN Mei, PAN Guo-Qing, LI Chun-Feng, ZHOU Ze-Yang. Sequence Analysis and Subcellular Localization of a Novel Nosema bombycis Gene in Saccharomyces cerevisiae Cells. Science of Sericulture. 2013, 39(2): 0302-0309. [In Chinese] [26]. LI Tian, QI Xiao-Ran, TAO Mei-Lin, ZHOU Ze-Yang, et al. Comparative Genomics Analysis of Secreted Proteins from Four Microsporidia. Science of Sericulture, 2013, 39(3):0527-0536. [In Chinese] [27]. LI Tian, LIU Xian-Lin, HAN Bing, ZHOU Ze-Yang, et al. Predicting and Analyzing Whole-genome Secreted Proteins of Microsporidian Nosema bombycis. Science of Sericulture, 2013, 39(2): 0295-0301. [In Chinese] [28]. Lin L, Pan G, Li T, Zhou Z, et al. The protein import pore Tom40 in the Microsporidian Nosema bombycis. J Eukaryot Microbiol, 20012, 59(3):251-257. [PubMed] [29]. Liu H, Pan G, Li T, Zhou Z, et al. Ultrastructure, chromosomal karyotype, and molecular phylogeny of a new isolate of microsporidian Vairimorpha sp. BM (Microsporidia, Nosematidae) from Bombyx mori in China. Parasitol Res, 2012, 110(1): 205-210. [PubMed] [30]. Li Z, Pan G, Li T, Zeyang Zhou, et al. SWP5, A Novel Spore Wall Protein Interaction with Polar Tube in the Parasite Nosema bombycis (Microsporidia). Eukaryotic Cell, 2012, 11: 229-237. [PubMed] [31]. Xu J, Wang L, Tang F, Zhou Z, et al. The nuclear apparatus and chromosomal DNA of the microsporidian Nosema antheraeae. J Eukaryot Microbiol, 2011, 58(2): 178-180. [PubMed] [32]. DENG Yuan-Hong, LI Neng-Zhang, LIN Li-Peng, ZHOU Ze-Yang, et al. The N-terminal Coding Sequence of Cell Division Cycle Protein of Nosema bombycis has Promoter Activity in Saccharomyces cerevisiae. Science of Sericulture, 2011, 37(4): 0688-0694. [In Chinese] [33]. Xiang H, Pan G, Zhang R, Zhou Z, et al. Natural selection maintains the transcribed LTR retrotransposons in Nosema bombycis. J Genet Genomics, 2010, 37: 305-314. [PubMed] [34]. Xiang H, Pan G, Vossbrinck CR, Zhou Z, et al. A tandem duplication of manganese superoxide dismutase in Nosema bombycis and its evolutionary origins. J Mol Evol, 2010, 71(5-6): 401-414. [PubMed] [35]. Xu J, Wang M, Zhang X, Zhou Z, et al. Identification of NbME MITE families: potential molecular markers in the microsporidia Nosema bombycis. J Invertebr Pathol, 2010, 103(1): 48-52. [PubMed] [36]. Li Y, Wu Z, Pan G, Zhou Z, et al. Identification of a novel spore wall protein (SWP26) from microsporidia Nosema bombycis.Int J Parasitol, 2009, 39(4): 391-398. [PubMed] [37]. Wu Z, Li Y, Pan G, Zhou Z, Xiang Z. SWP25, a novel protein associated with the Nosema bombycis endospore. J Eukaryot Microbiol, 2009, 56(2):113-118. [PubMed] [38]. Tian Li, Xiaoqun Dang, Guoqing Pan, Zeyang Zhou, et al. Mitochondrial Pyruvate Dehydrogenase E1 of Nosema bombycis – a Marker in Microsporidian Evolution. Current Zoology, 2009, 55: 423-429. [PDF] [39]. LI Tian, PAN Guo-Qing, DANG Xiao-Qun, ZHOU Ze-Yang. cDNA Library Construction and EST Analysis of Bombyx mori Silk Gland Heavily Infected by Nosema bombycis. Science of Sericulture, 2009, 35(2): 320-327. [In Chinese] [40]. Tao M, Pan G, Hu H, Zhou Z. Identification of a new serpin gene (NbSPN106) from Nosema bombycis. Wei Sheng Wu Xue Bao, 2009, 49(6): 726-32. [In Chinese] [41]. Wu Z, Li Y, Pan G, Zhou Z, et al. Proteomic analysis of spore wall proteins and identification of two spore wall proteins from Nosema bombycis (Microsporidia). Proteomics, 2008, 8(12):2447-2461. [PubMed] [42]. Liu H, Pan G, Song S, Zhou Z, et al. Multiple rDNA units distributed on all chromosomes of Nosema bombycis. J Invertebr Pathol, 2008, 99(2):235-238. [PubMed] [43]. Wu Z, Li Y, Pan G, Zhou Z, et al. A complete Sec61 complex in Nosema bombycis and its comparative genomics analyses. J Eukaryot Microbiol, 2007, 54(4): 379-380. [PubMed] [44]. Xu J, Pan G, Fang L, Zhou Z, et al. The varying microsporidian genome: existence of long-terminal repeat retrotransposon in domesticated silkworm parasite Nosema bombycis. Int J Parasitol, 2006, 36(9): 1049-1056. [PubMed]

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