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刘骁

领域:现代农业 学校:西南大学职称:副教授

期从事动物病毒的分子致病机制、非编码RNA与宿主互作机制及病毒控制技术的研究...

具体了解该专家信息,请致电:027-87555799 邮箱 haizhi@uipplus.com

教育背景

2014.10-2016. Research Fellow, Harvard Medical School, Massachusetts General Hospital. 哈佛大学医学院, 麻省总医院, 国家公派博士研究生 2012.9-2016.12. Ph.D. Sichuan Agriculture University, China. 四川农业大学, 博士 2010.9-2012.7. Master of Agriculture Science, Sichuan Agriculture Unࣺᯬ

工作经历

项目课题经历

1. 2018/07-2020/06,重庆市技术创新与应用示范项目--复合益生菌调控奶牛生产性能的关键技术集成与推广,西南大学,10万,主持 2. 2019/01-2020/12,重庆市留学人员创业创新支持计划--PEDV感染过程中lncRNAs调控机制的研究,西南大学,5万,主持 3. 2019/06-2021/12,中央高校基本科研业务费专项资金重点项目--干扰素诱导长链非编码RNA对PEDV感染的调控作用研究,西南大学,20万,主持 4. 2018/04-2019/12,中央高校基本科研业务费专项资金一般项目--非编码RNA对猪流行性腹泻病毒感染的调控机制研究,西南大学,10万,主持 5. 2018/07-2020/06,重庆市社会民生类重点研发项目--畜禽重要病原菌抗生素耐药性检测与控制技术研究,西南大学,50万,主研 6. 2018/01-2019/12,西南大学博士基金项目--长链非编码RNAs对多种人兽共患传染病感染的调控机制研究,10万,主持 7. 四川农业大学“全国优秀博士学位论文”培育基金,2012-2016,20万元,结题,主持 8. 核转录因子在猪繁殖与呼吸综合征病毒感染中的防制作用研究 (立项编号:2011FZ0065),结题,参研 9. 四川省“生猪现代产业链关键技术研究集成与产业化示范 ”项目 (2012NZ001),结题,参研 10. 猪伪狂犬病毒基因缺失疫苗(SA215株)生产配套技术研究 (2013NZ0016)(四川省2013年科技支撑计划项目),结题,参研

论文、成果、著作等

(1) Xiao Liu; Xiaoqiong Duan; Jacinta A. Holmes; Wenting Li; Sae Hwan Lee; Zeng Tu; Chuanlong Zhu; Shadi Salloum; Anna Lidofsky; Esperance A. Schaefer; Dachuan Cai; Shilin Li; Haoju Wang; Yongfu Huang; Yongju Zhao; Ming‐Lung Yu; Zhiwen Xu; Limin Chen; Jian Hong; Wenyu Lin ; Raymond T. Chung(*),A Long Noncoding RNA Regulates Hepatitis C Virus Infection Through Interferon Alpha–Inducible Protein 6. Hepatology 2019.2.28 69(3):1004~1019 (期刊论文,影响因子14.1) (2) Xiao Liu; Haoche Wei; Shan Liao; Jianheng Ye; Zhu Ling; Zhiwen Xu (#) MicroRNA transcriptome analysis of porcine vital organ responses to immunosuppressive porcine cytomegalovirus infection. Virology Journal 2018.15(1):16 (期刊论文,影响因子2.4) (3) Xiaoqiong Duan 1, Xiao Liu 1, Wenting Li, Jacinta A Holmes, Annie J Kruger, Chunhui Yang, Yujia Li, Min Xu, Haiyan Ye, Shuang Li, Xinzhong Liao, Qiuju Sheng, Dong Chen, Tuo Shao, Zhimeng Cheng, Batul Kaj, Esperance A Schaefer, Shilin Li, Limin Chen*, Wenyu Lin*, Raymond T Chung*. MicroRNA-130a downregulates HCV replication through an Atg5-dependent autophagy pathway. Cells, 2019, 8 (4), 338 (期刊论文,影响因子5.6) (4) Xiao Liu, Liao S, Xu Z*, Zhu L, Yang F, Guo W, Identification and Analysis of the Porcine MicroRNA in Porcine Cytomegalovirus-Infected Macrophages Using Deep Sequencing. PLoS ONE, 2016, 11(3): e0150971 (期刊论文,影响因子3.5) (5) Xiao Liu, Zhu L, Liao S, Xu Z*, Zhou Y, The Porcine MicroRNA Transcriptome Response to Transmissible Gastroenteritis Virus Infection. PLoS ONE, 2015, 10(3): e0120377 (期刊论文,影响因子3.5) (5) Xiao Liu, Xu Z*, Zhu L, Liao S, Guo W, Transcriptome Analysis of Porcine Thymus Following Porcine Cytomegalovirus Infection. PLoS ONE, 2014, 9(11): e113921 (期刊论文,影响因子3.5) (6) Xiao Liu, Liao S, Zhu L, Xu Z*, Zhou Y, Molecular Epidemiology of Porcine Cytomegalovirus (PCMV) in Sichuan Province, China: 2010–2012. PLoS ONE, 2013, 8(6): e64648 (期刊论文,影响因子4.1) (7) Xiao Liu, Zhu L, Xiaohong Shi, Xu Z*. Indirect-blocking ELISA for detecting antibodies against glycoprotein B (gB) of porcine cytomegalovirus (PCMV). Journal of Virological Methods, 2012, 186 (1–2): 30-35 (期刊论文,影响因子2.01) (8) 刘骁, 廖 珊, 朱 玲*, 周远成, 周 璐, 猪巨细胞病毒gB基因优势抗原表位区的原核表达及间接ELISA方法的建立.中国兽医科学. 2013, 43 (02):152-158. (9) 江一帆#, 刘 骁#, 廖珊, 朱玲*, 周远成猪巨细胞病毒gB优势抗原表位区的原核表达及其多克隆抗体的制备. 中国兽医科学. 2013, 43 (09): 936-940 (10) 廖珊#, 刘骁#, 朱玲, 徐志文*, 郭万柱乙型脑炎病毒NS3蛋白对其体外复制能力的影响. 中国兽医科学. 2013, 43 (11): 1122-1126. (11) 廖 珊#, 刘骁#, 朱玲*, 郭万柱, 猪乙型脑炎病毒SC-YA株部分生物学性状的研究. 中国兽医科学. 2013, 43 (10): 1006-1010. (13) Chuanlong Zhu; Fei Xiao; Jian Hong; Kun Wang; Dachuan Cai; Xiao Liu; Dahlene N. Fusco; Lei Zhao; Soung Won Jeong; Cynthia Brisac; Pattranuch Chusri;, Esperance A. Schaefer; Hong Zhao; Lee F. Peng; Wenyu Lin ; Raymond T. Chung*. EFTUD2 Is a Novel Innate Immune Regulator Restricting Hepatitis C Virus Infection through the RIG-I/MDA5 Pathway Journal of Virology. 2015.04.03 89(13): 6608~6617 (期刊论文,影响因子4.4) 论著之外的代表性研究成果和学术奖励 (1) Xiao Liu; Xiaoqiong Duan; Jacinta A. Holmes; Wenting Li; Shadi Salloum; Chuanlong Zhu; Esperance AK Schaefer; Dachuan Cai; Ming-Lung Yu; Jian Hong; Wenyu Lin; Raymond T. Chung. The mechanism of a novel lncRNA regulates HCV infection through IFI6 AASLD San Francisco 2018.11.9 2018.11.13 (会议报告) (2) Xiao Liu; Jian Hong; Dachuan Cai; Xiaoqiong Duan; Zeng Tu; Shadi Salloum; Jacinta A. Holmes; Anna Lidofsky; Zhiwen Xu; Wenyu Lin; Raymond T Chung. The mechanism of lncRNA IFI6 regulation of HCV infection Annual Meeting, of the American Association for the Study of Liver Diseases (AASLD) Boston, MA, USA 2016.10.11 2016.10.15 (会议报告) (3) Xiao Liu; Jian Hong; Dachuan Cai; Sae Hwan Lee; Dahlene Fusco; Esperance A. Schaefer; Cynthia Brisac; Anna Lidofsky; Wenyu Lin; Raymond T. Chung. Long noncoding RNAs regulate HCV replication and ISGs in a Jak-STAT independent manner Annual Meeting of the American Association for the Study of Liver Diseases (AASLD) Boston, MA, USA 2015.10.11 2015.10.15 (会议报告) 既非第一作者又非通讯作者论文 1. Wenyu Lin*, Chuanlong Zhu, Jian Hong, Lei Zhao, Nikolaus Jilg, Dahlene N. Fusco, Esperance A. Schaefer, Cynthia Brisac, Xiao Liu. The spliceosome factor SART1 exerts its anti-HCV action through mRNA splicing. Journal of hepatology, 2015, 62(5):1024-32 2. Zhu C, Xiao F, Hong J, Wang K, Liu X, Cai D, Fusco DN, Zhao L, Jeong SW, Brisac C, Chusri P, Schaefer EA, Zhao H, Peng LF, Lin W, Chung RT*. EFTUD2 is a novel innate immune regulator restricting hepatitis C virus infection through the RIG-I/MDA5 pathway. Journal of virology, 2015, 89 (13): 6608-18 3. Yuhan Cai , Ling Zhu, Yuanchen Zhou, Xiao Liu, Xiaowan Liu, Xinqiong Li, Qiaoli Lang, Xiaogai Qiao, Zhiwen Xu*. Identification and Analysis of Differentially-Expressed microRNAs in Japanese Encephalitis Virus-Infected PK-15 Cells with Deep Sequencing. Int. J. Mol. Sci. 2015, 16, 2204-2219. 4. 周璐, 周远成, 魏浩澈, 付梦瑾, 刘骁, 季洪伟, 朱玲*, 猪环曲病毒实时荧光定量RT-PCR检测方法的建立与应用. 中国兽医科学. 2013, 43 (09): 952-957. 会议论文 1. Xiao Liu, Jian Hong, Dachuan Cai, Sae Hwan Lee, Dahlene Fusco, Raymon Chung*, Long noncoding RNAs regulate HCV replication and ISGs in a Jak-STAT independent manner. Annual Meeting of the American Association for the Study of Liver Diseases (AASLD) Boston, MA, USA 2015.10.11-2015.10.15. 2. Xiao Liu, Jian Hong, Dachuan Cai, Xiaoqiong Duan, Zeng Tu, Salloum Shadi, Jacinta Holmes, Zhiwen Xu, Wenyu Lin, Raymond T. Chung*, The mechanism of lncRNA IFI6 regulation of HCV infection. Annual Meeting of the American Association for the Study of Liver Diseases (AASLD) Boston, - MA, USA 2016.10.11-2016.10.15 3. Xiao Liu, Xiaoqiong Duan, Jacinta A. Holmes, Wenting Li, Shadi Salloum, Chuanlong Zhu, Esperance AK Schaefer, Dachuan Cai, Ming-Lung Yu, Jian Hong, Wenyu Lin, Raymond T. Chung*. The mechanism of a novel lncRNA regulates HCV infection through IFI6. Annual Meeting of the American Association for the Study of Liver Diseases, San Francisco, 2018.11.9-2018.11.13

专利、著作版权等

1. 猪巨细胞病毒抗体间接阻断ELISA检测试剂盒及其检测方法,2015.4.22,中国, CN102621305 B 2. 一种猪细环病毒II型抗体间接阻断elisa检测试剂盒,2015.2.25,中国,CN102621305 B
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