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李利

领域:现代农业 学校:四川农业大学职称:教授

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教育背景

2001/9–2005/7, 四川农业大学, 动物遗传育种与繁殖, 博士 1995/9–1998/7, 四川农业大学, 动物遗传育种与繁殖,硕士 硕士1991/9–1995/7, 四川农业大学, 畜牧学, 学士

工作经历

2012/1-至今,四川农业大学,动物科技学院,教授 2007/1-2011/12,四川农业大学,动物科技学院,副教授 2002/1-2006/12,四川农业大学,动物科技学院,讲师 2008/3-2013/3,北京畜牧兽医研究所,博士后 2009/7-2010/6, 悉尼大学 访问学者

项目课题经历

国家自然科学基金面上项目,山羊骨骼肌细胞分化中H19-MyoD轴相关的核心lncRNAs调控网络构建(31672402),58万,2017/01-2020/12,主持 国家自然科学基金面上项目,环状RNA CDR1as在山羊骨骼肌卫星细胞分化中的作用及分子海绵机制(31772578),61万,2018/01-2021/12,主研 四川省科技创新产业链示范工程项目,山羊现代产业链关键技术集成研究与产业化示范(2014NZ0001),100万,2014/01-2016/12,主研 四川省育种攻关项目,南江黄羊配套系的选育(2011NZ0099-33),60万,2011/01-2015/12,主研 国家自然科学基金面上项目,绵羊全基因组CNVs及其与肌肉生长的关联分析(30972094),2010/01-2012/12,35万,主研

论文、成果、著作等

Li Li, Yuan Chen, Lu Nie, Xue Ding, Xiao Zhang, Wei Zhao, Xiaoli Xu, Bismark Kyei, Dinghui Dai, Siyuan Zhan, Jiazhong Guo, Tao Zhong, Linjie Wang, Hongping Zhang, MyoD-induced circular RNA CDR1as promotes myogenic differentiation of skeletal muscle satellite cells, Biochim Biophys Acta Gene Regul Mech. 2019 Aug;1862(8):807-821. doi: 10.1016/j.bbagrm.2019.07.001. Epub 2019 Jul 16. Li Li, Bingbing Shen, Siqi Dai, Zhenhai Tang, Wei Zhao, Siyuan Zhan, Linjie Wang, Tao Zhong,Jiazhong Guo, Hongping Zhang*. The novel mutations in the MEF2C gene associate with growth of Nanjiang Yellow goats. Gene Reports, 2019,14: 100-109 Yongfeng Zhang#, Li Li#, Qin Wang, Siyuan Zhan, Linjie Wang, Tao Zhong ,Jiazhong Guo, Hongping Zhang*.Fibroblast Growth Factor 21 induces lipolysis more efficiently than it suppresses lipogenesis in goat adipocytes, Cytotechnology 2018, 70(5): 1423-1433. //doi.org/10.1007/ s10616-018-0237-1 Wei Zhao#, Li Chen#, Tao Zhong, Linjie Wang, Jiazhong Guo, Yao Dong , Jing Feng, Tianzeng Song, Li Li* , Hongping Zhang*,The differential proliferation and differentiation ability of skeletal muscle satellite cell in Boer and Nanjiang brown goats, Small Ruminant Research, 2018, 169:99-107 Wei Zhao#, Hailong Yang#, Juntao Li, Yuan Chen, Jiaxue Cao, Tao Zhong, Linjie Wang,Jiazhong Guo, Li Li*, Hongping Zhang*, MiR-183 promotes preadipocyte differentiation by suppressing Smad4 in goats, 2018, Gene,666: 158-164 Liu Yang,Lingyang Xu,Yang Zhou,Mei Liu,Lei Wang,James W.Kijas,Hongping Zhang,Li Li*,George E. Liu*, Diversity of copy number variation in a worldwide population of sheep,Genomics 2018,110(3):143-148. Zhan SY, Dong Y, Zhao W, Guo J, Zhong T, Wang LJ, Li L, Zhang HP: Genome-wide identification and characterization of long non-coding RNAs in developmental skeletal muscle of fetal goat. BMC Genomics 2016, 17. Wei Caihong, Li Li, Su Hongwei, Xu Lingyang, Lu Jian, Zhang Li, Liu Wenzhong, Ren Hangxing, Du Lixin(*), Identification of the crucial molecular events during the large-scale myoblast fusion in sheep.,Physiological Genomics, 2014, 46(12): 429-440. Xu Lingyang, Zhao Fuping, Ren, Hangxing, Li, Li, Lu Jian, Liu Jiasen, Zhang Shifang, George E Song jiuzhou, Zhang Li, Wei Caihong, Du Lixin, Co-expression analysis of fetal weight-related genes in ovine skeletal muscle during mid and late fetal development stages. Int J Biol Sci,2014,10(9):1039-1050. Li Li, Jiang Jing,Wang Linjie, Zhong Tao, Chen Bo, Zhan Siyuan, Zhang Hongping, Du Lixin, Expression patterns of peroxisome proliferator-activated receptor gamma 1 versus gamma 2, and their association with intramuscular fat in goat tissues. Gene, 2013, 528(2):195-200. Wang Linjie, Li Li, Jiang Jing, Wang Yan, Zhong Tao, Chen Yu, Wang Yong, Zhang Hongping, Molecular characterization and different expression patterns of the FABP gene family during goat skeletal muscle development. Mol Biol Rep, 2015, 42(1): 201-207. Jiaxue Cao, Caihong Wei, Dongming Liu, Huihua Wang, Mingming Wu, Zhiyuan Xie, Terence D. Capellini, Li Zhang, Fuping Zhao, Li Li, Tao Zhong, Wang Linjie, Jian Lu, Ruizao Liu, Shifang Zhang, Yongfei Du, Hongping Zhang*, Lixin Du*, DNA Methylation Landscape of Body Size Variation in Sheep, Scientific Reports, 2015(5):13950, DOI: 10.1038/srep13950 Chen Li, Cheng Bo, Li Li, Zhan Siyuan, Wang Linjie, Zhong Tao, Chen Yu, Zhang Hongping, The molecular characterization and temporal-spatial expression of myocyte enhancer factor 2 genes in the goat and their association with myofiber traits. Gene, 2015, 555(2): 223-230. Li Dandan, Zhan Siyuan, Wang Yilin, Wang Linjie, Zhong Tao, Li Li, Fan Jingsheng, Xiong Chaorui,Wang Yong, Zhang Hongping, Role of microRNA-101a in the regulation of goat skeletal muscle satellite cell proliferation and differentiation. Gene, 2015, 572(2): 198-204. Wang Cen, Zhang Hao, Niu Lili, Guo Jiazhong, Jia Xianbo,Wang Linjie, Li Li, Zhang Hongping, Zhong Tao,The novel SNPs of leptin gene and their associations with growth traits in Chinese Nanjiang Yellow goat. Gene, 2015, 572(1): 35-41. Wei Caihong, Ren Hangxing, Xu Lingyang, Li Li, Liu Ruizao, Zhang Li, Zhao Fuping, Lu Jian, Zhang Xiaoning, Du Lixin, Signals of Ezh2, Src, and Akt Involve in myostatin-Pax7 pathways regulating the myogenic fate determination during the sheep myoblast proliferation and differentiation. PLoS One, 2015, 10(3): e0120956-e0120956. Hou Yuguo,Wang Yilin, WangYan, ZhongTao, Li Li, Zhang Hongping, Wang Linjie, Multiple alternative splicing and differential expression pattern of the glycogen synthase kinase-3beta (GSK3beta) gene in goat (Capra hircus). PLoS One, 2014, 9(10): e109555-e109555. Zhong Tao, Jin Peng-Fei, Dong En-Ni, Li Li, Wang Lin-Jie, Zhang Hong-Ping, Caprine sex affects skeletal muscle profile and MRFs expression during postnatal development. Anim Sci J, 2013, 84(5): 442-448. 陈利,赵薇,占思远,李丹,李利,仲涛,王林杰,张红平,山羊不同组织及不同发育时期骨骼肌内参基因的表达稳定性分析,畜牧兽医学报,2014,(08):1228-1236. 参与编写的专著 (1) 张红平,吴登俊,张柱国,杨永林,魏彩虹,李利,马友记,张凤霞,谢之景, 王林杰,仲 涛,占思远,邓中宝,陈小琴,绵羊标准化规模养殖图册,中国农业出版社, 2013。 (2) 明道绪,刘学洪,张红平,宋代军,郭春华,李利,徐向宏,金凤,蔡惠芬,张 豪,高鹏飞,陈静,安晓萍,生物统计附试验设计(第五版),中国农业出版社,2014。 (3) 魏彩虹,杜立新,刘长春,石国庆,李利,肉羊标准化养殖技术图册,中国农业科学技术,2012。

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