教育背景
2002.09 – 2007.12,中国农业大学动物科技学院,动物遗传育种与繁殖系,攻读博士学位
1994.10 – 1998.7,东北林业大学野生动物资源学院,野生动物保护与利用,攻读学士学位
工作经历
2013.12 -今,四川农业大学,动物科技学院,教授
2014.08 – 2015.08,美国犹他州立大学,动物乳品和兽医科学系,访问学者
2009.12 – 2013.11,四川农业大学,动物科技学院,副教授
2008.03 – 2011.03,农业生物技术国家重点实验室,博士后
2007.05 – 2007.07,匈牙利农业生物技术中心,访问学者
2006.12 – 2009.11,四川农业大学,旅游学院,讲师
2001.09 – 2002.08,四川农业大学都江堰校区,助讲
1998.07 – 2001.08,四川省林业学校,助讲
项目课题经历
1. Cd9表观遗传修饰影响超低温冷冻牛卵母细胞受精潜力的研究,国家自然科学基金面上项目(31572398),2016.1-2019.12,主持;
2. 强化褪黑素功能乳的转基因奶山羊新品种培育,国家科技重大专项(项目号:2014ZX08008-002B),2014.1-2016.12,二级子课题主持;
3. 奶牛高效繁殖技术集成与应用,国家奶牛产业技术体系,2015.1-2020.12,子课题主持
论文、成果、著作等
1. Zhou GB(*), Zeng Y, Meng QG, Liu Y, Dai YP, Zhu SE, Bunch TD, Hou YP(*). 2013. Decreased expression of CD9 in bovine oocytes after cryopreservation and the relationship to fertilization capacity. Mol Reprod Dev 80(6):451-459.
2. Zhou GB, Meng QG, Li N(*). 2010. In vitro derivation of germ cells from embryonic stem cells in mammals. Mol Reprod Dev 77(7):586-594.
3. Zhou GB, Ma CB, Liu GS(*), Zhu SE, Zhang HH, Jia LL, Suo L, Shi JM, Wang YB, Tian JH, Zeng SM. 2009b. Vitrification of farmed blue fox oocytes in ethylene glycol and dmso-based solutions using open-pulled straw (OPS). Cryo Letters 30(2):112-118.
4. Zhou GB, Liu GS, Meng QG, Liu Y, Hou YP, Wang XX, Li N, Zhu SE(*). 2009a. Tetraspanin CD9 in bovine oocytes and its role in fertilization. J Reprod Dev 55(3):305-308.
5. Zhou GB(*), Li N. 2013. Bovine oocytes cryoinjury and how to improve their development following cryopreservation. Anim Biotechnol 24(2):94-106.
6. Zhou GB, Li N(*). 2009. Cryopreservation of porcine oocytes: recent advances. Mol Hum Reprod 15(5):279-285.
7. Zhou GB, Hou YP, Jin F, Yang QE, Yang ZQ, Quan GB, Tan HM, Zhu SE(*). 2005. Vitrification of mouse embryos at various stages by open-pulled straw (OPS) method. Anim Biotechnol 16(2):153-163.
8. Li W, Cheng K, Zhang Y, Meng Q, Zhu S,Zhou G(*). 2015. No effect of exogenous melatonin on development of cryopreserved metaphase II oocytes in mouse. Journal of animal science and biotechnology 6(1):42.
9. Li Q, Wang H,Zhou GB(*), Jinfei M, Yan L, Zhaihu Z, Li N(*). 2014. Production of healthy cloned pigs with neural stem cells as nuclear donors. Anim Biotechnol 25(4):294-305.
10. Zhou Y, Fu X, Zhou G, Jia B, Fang Y, Hou Y, Zhu S(*). 2014. An efficient method for the sanitary vitrification of bovine oocytes in straws. Journal of animal science and biotechnology 5(1):19.
11. Zhou C,Zhou GB, Zhu SE(*), Hou YP, Jin F, Zhao XM, Hong QH. 2007. Open-pulled straw (OPS) vitrification of mouse hatched blastocysts. Anim Biotechnol 18(1):45-54.
12. Zhao XM, Quan GB,Zhou GB, Hou YP, Zhu SE(*). 2007. Conventional freezing, straw, and open-pulled straw vitrification of mouse two pronuclear (2-PN) stage embryos. Anim Biotechnol 18(3):203-212.
13. Zhang QJ,Zhou GB, Wang YP, Fu XW, Zhu SE(*). 2012. Cryoprotectants protect medaka (Oryzias latipes) embryos from chilling injury. Cryo Letters 33(2):108-117.
14. Zeng Y, Fu X,Zhou G, Yue M, Zhou Y, Zhu S(*). 2013. Expression and distribution of cell adhesion-related proteins in bovine parthenogenetic embryos: The effects of oocyte vitrification. Theriogenology 80(1):34-40.
15. Yue MX, Fu XW, Zhou GB, Hou YP, Du M, Wang L, Zhu SE(*). 2012. Abnormal DNA methylation in oocytes could be associated with a decrease in reproductive potential in old mice. J Assist Reprod Genet 29(7):643-650.
16. Yang ZQ,Zhou GB, Hou YP, Yan CL, Zhu SE(*). 2007b. Effect of in-straw thawing on in vitro- and in vivo-development of vitrified mouse morulae. Anim Biotechnol 18(1):13-22.
17. Yang QE, Hou YP,Zhou GB, Yang ZQ, Zhu SE. 2007a. Stepwise in-straw dilution and direct transfer using open pulled straws (OPS) in the mouse: a potential model for field manipulation of vitrified embryos. J Reprod Dev 53(2):211-218.
18. Yan CL, Yang QE, Zhou GB, Hou YP, Zhao XM, Fan ZQ, Liu MQ, Liu L, Zhu SE(*). 2008. Open-pulled straw (OPS) vitrification of in vitro fertilised mouse embryos at various stages. Acta Vet Hung 56(2):245-253.
19. Yan CL, Fu XW,Zhou GB, Zhao XM, Suo L, Zhu SE(*). 2010. Mitochondrial behaviors in the vitrified mouse oocyte and its parthenogenetic embryo: effect of Taxol pretreatment and relationship to competence. Fertil Steril 93(3):959-966.
20. Xia W, Fu XW,Zhou GB, Xu J, Wang L, Du M, Yuan DS, Yue MX, Tian JH, Zhu SE(*). 2013. Cytokeratin distribution and expression during the maturation of mouse germinal vesicle oocytes after vitrification. Cryobiology 66(3):261-266.
21. Wusiman A, Wang YP, Ren K,Zhou GB, Fu XW, Suo L, Fan ZQ, Wang L, Zhu SE(*). 2012. Semen Storage at 23, 4 or -196°C and its Application to Artificial Insemination in Small-tail Han Sheep. Asian Journal of Animal and Veterinary Advances 7(4):299-308.
22. Wu GQ, Jia BY, Li JJ, Fu XW,Zhou GB, Hou YP, Zhu SE(*). 2011. L-carnitine enhances oocyte maturation and development of parthenogenetic embryos in pigs. Theriogenology 76(5):785-793.
23. Wang YP,Zhou GB, Zeng Y, Li JJ, Zhang QJ, Hou YP, Zhu SE(*). 2011b. Impact on Hyperactivated Motility of Cryopreserved Mouse Sperm from Pretreatment with Thimerosal. Asian Journal of Animal and Veterinary Advances 6(11):1052-1060.
24. Wang YP, Zhao XM,Zhou GB, Hou YP, Fan ZQ, Yan CL, Suo L, Fu XW, Zhu SE(*). 2008. Production of normal offspring from partially zona-incised vitrified mouse oocytes fertilized with cryopreserved spermatozoa using an optimized protocol. Cryo Letters 29(2):111-119.
25. Wang L, Zhuo ZY, Shi WQ, Tan DX, Gao C, Tian XZ, Zhang L,Zhou GB, Zhu SE(*), Yun P, Liu GS. 2014. Melatonin Promotes Superovulation in Sika Deer (Cervus nippon). International journal of molecular sciences 15(7):12107-12118.
26. Wang L,Zhou GB,Shi WQ, Shi JM, Tian XZ, Gao C, Zhang L, Zhu SE, Zhang TT, Zeng SM, Liu GS(*). 2012. First live offspring born in superovulated sika deer (Cervus nippon) after embryo vitrification. Theriogenology 78(7):1627-1632.
27. Wang L, Liu J, Zhou GB, Hou YP, Li JJ, Zhu SE(*). 2011a. Quantitative investigations on the effects of exposure durations to the combined cryoprotective agents on mouse oocyte vitrification procedures. Biol Reprod 85(5):884-894.
28. Tian XZ, Wen Q, Shi JM, Liang W, Zeng SM, Tian JH,Zhou GB, Zhu SE, Liu GS(*). 2010. Effects of Melatonin on In Vitro Development of Mouse Two-Cell Embryos Cultured in HTF Medium. Endocr Res 35(1):17-23.
29. Tian SJ, Yan CL, Yang HX,Zhou GB,Yang ZQ, Zhu SE(*). 2007. Vitrification solution containing DMSO and EG can induce parthenogenetic activation of in vitro matured ovine oocytes and decrease sperm penetration. Anim Reprod Sci 101(3-4):365-371.
30. Suo L,Zhou GB, Meng QG, Yan CL, Fan ZQ, Zhao XM, Fu XW, Wang YP, Zhang QJ, Zhu SE(*). 2009b. OPS vitrification of mouse immature oocytes before or after meiosis: the effect on cumulus cells maintenance and subsequent development. Zygote 17(1):71-77.
31. Suo L, Wang F,Zhou GB, Shi JM, Wang YB, Zeng SM, Tian JH, Zhu SE, Liu GS(*). 2009a. Optimal concentration of calcium and electric field levels improve tetraploid embryo production by electrofusion in mice. J Reprod Dev 55(4):383-385.
32. Shi JM, Tian XZ,Zhou GB, Wang L, Gao C, Zhu SE, Zeng SM, Tian JH, Liu GS(*). 2009. Melatonin exists in porcine follicular fluid and improves in vitro maturation and parthenogenetic development of porcine oocytes. J Pineal Res 47(4):318-323.
33. Liu GS(*),Zhou GB, Zhang HH, Ma CB, Shi WQ, Zhu SE, Yang ZQ, Kang J, Jia LL, Zeng SM, Tian JH, Wang F. 2008. Surgical embryo transfer resulted in birth of live offspring in farmed blue fox. Anim Reprod Sci 105(3-4):424-429.
34. Li JJ, Pei Y,Zhou GB,Suo L, Wang YP, Wu GQ, Fu XW, Hou YP, Zhu SE(*). 2011. Histone deacetyltransferase1 expression in mouse oocyte and their in vitro-fertilized embryo: effect of oocyte vitrification. Cryo Letters 32(1):13-20.
35. Gao C, Han HB, Tian XZ, Tan DX, Wang L,Zhou GB, Zhu SE, Liu GS(*). 2012. Melatonin promotes embryonic development and reduces reactive oxygen species in vitrified mouse 2-cell embryos. J Pineal Res 52(3):305-311.
36. Fu XW, Wu GQ, Li JJ, Hou YP,Zhou GB, Lun S, Wang YP, Zhu SE(*). 2011. Positive effects of Forskolin (stimulator of lipolysis) treatment on cryosurvival of in vitro matured porcine oocytes. Theriogenology 75(2):268-275.
37. Fu XW, Shi WQ, Zhang QJ, Zhao XM, Yan CL, Hou YP,Zhou GB, Fan ZQ, Suo L, Wusiman A, Wang YP, Zhu SE(*). 2009. Positive effects of Taxol pretreatment on morphology, distribution and ultrastructure of mitochondria and lipid droplets in vitrification of in vitro matured porcine oocytes. Anim Reprod Sci 115(1-4):158-168.
38. Fan ZQ, Li XW, Liu Y, Meng QG, Wang YP, Hou YP,Zhou GB, Zhu SE(*). 2008. Piezo-assisted in vitro fertilization of mouse oocytes with spermatozoa retrieved from epididymides stored at 4 degree C. J Reprod Dev 54(2):107-112.
39. Cheng J, Jia B, Wu T, Zhou G, Hou Y, Fu X, Zhu S(*). 2014. Effects of vitrification for germinal vesicle and metaphase II oocytes on subsequent centromere cohesion and chromosome aneuploidy in mice. Theriogenology 82(3):495-500.
教材与专著
1. 《动物克隆与基因组编辑》中国农业大学出版社第1版(2012.7)参编
2. 《动物配子与胚胎冷冻保存原理及应用》科学出版社第1版(2012.2)副主编
3. 《特种经济动物生产学》科学出版社第1版(2009.5)参编
四、研究方向与在研项目
专利、著作版权等
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