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周鹏

领域:生物产业 学校:电子科技大学职称:副教授

1.结构生物信息学 2.计算生物学 3.计算机辅助药物设计...

具体了解该专家信息,请致电:027-87555799 邮箱 haizhi@uipplus.com

教育背景

2000/09-2004/07 重庆大学化学与化工学院,材料化学,学士 2004/09-2007/07 重庆大学化学与化工学院,药物化学,硕士 2007/09-2011/03 浙江大学理学院化学系,化学,博士

工作经历

2011/05-至今 电子科技大学生命科学与技术学院,副教授 2012/10-2013/10 美国食品药品监督管理局(U.S. FDA)国家药物毒理学研究中心(NCTR),博士后

项目课题经历

论文、成果、著作等

1. Zhou P*, Zhang S, Wang C, Wang Y, Yang C, Huang J. Structural modeling of HLA-B*1502/peptide/carbamazepine/T-cell receptor complex architecture: implication for the molecular mechanism of carbamazepine-induced. Stevens-Johnson syndrome/toxic epidermal necrolysis. J. Biomol. Struct. Dyn. 2016, 34: 1806–1817. 2. Yang C, Zhang S, Bai Z, Hou S, Wu D, Huang J, Zhou P*. A two-step binding mechanism for the self-binding peptide recognition of target domains. Mol. BioSyst. 2016, 12: 1201–1213. 3. Yang C, Zhang S, He P, Wang C, Huang J, Zhou P*. Self-binding peptides: folding or binding? J. Chem. Inf. Model. 2015, 55: 329−342. 4. Yang C, Wang C, Zhang S, Huang J*, Zhou P*. Structural and energetic insights into the intermolecular interaction among human leukocyte antigens, clinical hypersensitive drugs and antigenic peptides. Mol. Simul. 2015, 41: 741−751. 5. Zhou P*, Wang C, Ren Y, Yang C, Tian F*. Computational peptidology: a new and promising approach to therapeutic peptide design. Curr. Med. Chem. 2013, 20: 1985−1996. (ESI highly cited paper) 6. Zhou P*, Yang C, Ren Y, Wang C, Tian F*. What are the ideal properties for functional food peptides with antihypertensive effect? A computational peptidology approach. Food Chem. 2013, 141: 2967−2973. 7. Zhou P*, Wang C, Tian F, Ren Y, Yang C, Huang J*. Biomacromolecular quantitative structure-activity relationship (BioQSAR): a proof-of-concept study on the modeling, prediction and interpretation of protein-protein binding affinity,J. Comput. Aid. Mol. Des. 2013, 27: 67−78. 8. Zhou P*, Huang J, Tian F*. Specific noncovalent interactions at protein–ligand interface: implications for rational drug design. Curr. Med. Chem. 2012, 19: 226−238.

专利、著作版权等

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