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游自立

领域:生物产业 学校:电子科技大学职称:教授

1. 神经免疫学与认知行为 2. 神经药理学研究与天然药物开发...

具体了解该专家信息,请致电:027-87555799 邮箱 haizhi@uipplus.com

教育背景

1980.09——1985.07 泸州医学院中医系 大学本科/中医学学士 1985.07——1987.09 涪陵卫生学校 助讲 1987.09——1990.07 成都中医药大学基础医学院 研究生/医学硕士1995.09——1998.07 华西医科大学基础医学院 研究生/医学博士

工作经历

1990.07——1995.09 成都中医药大学微生物免疫学教研室 讲师 1995.09——1998.07 华西医科大学基础医学院 研究生/医学博士 1998.07——2003.03 华西医科大学钩体病研究室 讲师 2003.03——2008.08 电子科大生命科学与技术学院生物技术系主任 副教授 2005.03——2005.09 California University at Berkeley 访问学者 2008.08——现在 电子科大生命科学与技术学院 教授/博士生导师

项目课题经历

论文、成果、著作等

1. Zhao Q, Wu X, Yan S, Xie X, Fan Y, Zhang J, Peng C, *You Z. The antidepressant-like effects of pioglitazone in a chronic mild stress mouse model are associated with PPARγ mediated alteration of microglial activation phenotypes J Neuroinflammation. 2016 Oct 4;13(1):259 2. Zhang JQ, Wu XH, Feng Y, Xie XF, Fan YH, Yan S, Zhao QY, Peng C, *You ZL. Salvianolic acid B ameliorate depressive-like behaviors in chronic mild stress-treated mice: involvement of the neuroinflammatory pathway Acta Pharmacol Sin, 2016;37(9):1141-53 3 Yan S, Zhao Q, Peng C, He G, Gou X, Lin B, *You Z. Antidepressant-like effects of Sanyuansan in the mouse forced swim, tail suspension tests and chronic mild stress model Kaohsiung J Med Sci. 2015 Dec;31(12):605-12 4. Zhao Q, Xie X, Fan Y, Zhang J, Jiang W, Wu X, Yan S, Chen Y, Peng C, *You Z. Phenotypic dysregulation of microglial activation in young offspring rats with maternal sleep deprivation-induced cognitive impairment. Sci Rep. 2015;5:9513 5. Zhao Q, Peng C, Wu X, Chen Y, Wang C, *You Z. Maternal Sleep Deprivation Inhibits Hippocampal Neurogenesis Associated with Inflammatory Response in Young Offspring Rats Neurobiol Dis. 2014 Aug;68:57-65 6. Feng Y, *You Z, Yan S, He G, Chen Y, Gou X, Peng C. Antidepressant-like effects of Salvianolic acid B in the mouse forced swim and tail suspension tests. Life Sci. 2012 Jun 27;90(25-26):1010-4 7. *You Z, Luo C, Zhang W, Chen Y, He J, Zhao Q, Zuo R, Wu Y. Pro- and anti-inflammatory cytokines expression in rat's brain and spleen exposed to chronic mild stress: Involvement in depression. Behav Brain Res. 2011 Nov 20;225(1):135-41 8. *You ZL, Xia Q, Liang FR, Tang YJ, Xu CL, Huang J, Zhao L, Zhang WZ, He JJ. Effects on the expression of GABAA receptor subunits by jujuboside A treatment in rat hippocampal neurons. J Ethnopharmacol. 2010 Mar 24;128(2):419-23 9. Yi Y, You Z, Yao D, Yang J, Zhou G, Tang X. Screening for Obstructive Sleep Apnea by STOP and Berlin Questionnaires in Chinese Patients. 25th Anniversary Meeting of the Associated Professional Sleep Societies (APSS) on June 11-15, 2011, Minnesota (Sleep. 2011;34(Supple):A129) 10. Wang C, *You ZL, Zhang DD. Down-regulation of APLP1 mRNA expression in hippocampus of pilocarpine-induced epileptic rats Neurosci Bull. 2009; 25(3):109-114 11. Wang C, *You ZL, Xia Q, Xiong T, Xia Y, Yao DZ. Upregulation of Mark3 and Rpgrip1 mRNA expression by jujuboside A in mouse hippocampus Acta Pharmacol Sin 2007;28 (3):334–338 12. *Ma Y, Sun JN, Xu QP, You ZL, Guo YJ. 3,4-oxo-isopropylidene-shikimic acid inhibits adhesion of polymorphonuclear leukocyte to TNF-a-induced endothelial cells in vitro. Acta Pharmacol Sin, 2004;25(2):246-50

专利、著作版权等

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