2002年毕业于山东济宁医学院临床医学专业，2007年在中山大学获博士学位

自2014年1月至今任中山医学院生理教研室副教授

科研项目研究课题：

增强背侧海马锥体神经元兴奋抑制外周神经损伤引起的神经病理性疼痛的作用及其机制研究（No.81870969)国家自然科学基金面上项目56万2019.1～2022.12 负责人 脊髓背角肝X受体抑制致炎细胞因子表达促进神经病理性疼痛恢复的作用及其机制（No. 81471250）国家自然科学基金面上项目70万2015.1～2018.12 负责人 胶质细胞TSPO抗神经病理性疼痛的机制（No. 81200856）国家自然科学青年基金23万2013.1～2015.12 负责人 L-苏糖酸镁对化疗药物引起的神经病理性疼痛的预防作用及其机制，广东省科技计划项目10万，2016A020215035， 2016.1～2018.12负责人 脊髓背角肝X受体对神经病理性疼痛的调制作用及其机制（No. 13ykpy05）青年教师培育项目 15万 2014.1～2016.12负责人 DRG LXRs 抑制外周敏感化促进神经病理性疼痛恢复的作用及其机制.广东省自然科学基金面上项目10万2015.1～2017.12负责人 TSPO激动剂抑制神经病理性疼痛的作用及其机制（No：20100171120053）教育部新教师基金3.6万 2011.1～2013.12负责人 TSPO在神经病理性疼痛中的作用及其机制（No：LYM1005）广东省教育厅育苗工程基金3万 2010.10～2012.10 负责人 TSPO抑制致炎细胞因子表达在神经病理性疼痛中的作用及其机制（No：B2011064）广东省卫生厅0.5万 2011.1～2013.12负责人

迄今为止发表了20 余篇相关论文。发表论文:

Yang T, Du Sj, Liu XG, Ye XJ, Wei XH*. (2018) Withdrawal from spinal application of remifentanil induces long-term potentiation of c-fiber-evoked field potentials by activation of Src family kinases in spinal microglia. Neurochemical Research 43:1660-670 (IF:2.8) (通讯作者). Wang W, Zhong X, Li Y, Guo R, Du S, Wen L, Ying Y, Yang T, Wei XH. Rostral ventromedial medulla-mediated descending facilitation following P2X7 receptor activation is involved in the development of chronic post-operative pain. J Neurochem. 2018 Dec 20. doi: 10.1111/jnc.14650. [Epub ahead of print] (通讯作者) Song J, Ying Y, Wang W, Liu X, Xu X*, Wei X*, Ruan X* (2017) The role of P2X7R/ERK signaling in dorsal root ganglia satellite glial cells in the development of chronic postsurgical pain induced by skin/muscle incision and retraction (SMIR). Brain, behavior, and immunity (IF:5.8) (并列通讯作者). Xu J, Feng YW, Liu L, Wang W, Zhong XX, Wei XH*, Liu XG (2017) Liver X Receptor alpha Is Involved in Counteracting Mechanical Allodynia by Inhibiting Neuroinflammation in the Spinal Dorsal Horn. Anesthesiology 127:534-547 (IF:5.2) (独立通讯作者). Xu J, Wang W, Zhong XX, Feng Y, Wei X*, Liu XG* (2016) EXPRESS: Methylcobalamin ameliorates neuropathic pain induced by vincristine in rats: Effect on loss of peripheral nerve fibers and imbalance of cytokines in the spinal dorsal horn. Molecular pain 12 (IF:3.0) (并列通讯作者). Chen SL, Zang Y, Zheng WH, Wei XH, Liu XG (2016) Inhibition of Neuropathic Pain by a Single Intraperitoneal Injection of Diazepam in the Rat: Possible Role of Neurosteroids. The Chinese journal of physiology 59:9-20 (IF:1.2) (独立通讯作者). Zhu HQ, Xu J, Shen KF, Pang RP, Wei X*, Liu XG* (2015) Bulleyaconitine A depresses neuropathic pain and potentiation at C-fiber synapses in spinal dorsal horn induced by paclitaxel in rats. Exp. Neurol. 273:263-272 (IF:4.7) (并列通讯作者). Ying YL#, Wei XH#, Xu XB, She SZ, Zhou LJ, Lv J, Li D, Zheng B, Liu XG. Over-expression of P2X7 receptors in spinal glial cells contributes to the development of chronic postsurgical pain induced by skin/muscle incision and retraction (SMIR) in rats. Exp. Neurol. 261, 836-843, 2014 (IF:4.6) (Co-first author) (IF:4.6) Wei XH, Wei X, Chen FY, Zang Y, Xin WJ, Pang RP, Chen Y, Wang J, Li YY, Shen KF, Zhou LJ, Liu XG. The Upregulation of Translocator Protein (18 kDa) Promotes Recovery from Neuropathic Pain in Rats. J. Neurosci. 33, 1540-1551, 2013 (IF:6.9) (First author) Wei XH, Na XD, Liao GJ, Chen QY, Cui Y, Chen FY, Li YY, Zang Y, Liu XG. The up-regulation of IL-6 in DRG and spinal dorsal horn contributes to neuropathic pain following L5 ventral root transection. Exp. Neurol. 241,159-68, 2013 (IF:4.6) (first author) Li YY #, Wei XH #, Lu ZH, Chen JS, Huang QD, Gong QJ. Src/p38 MAPK pathway in spinal microglia is involved in mechanical allodynia induced by peri-sciatic administration of recombinant rat TNF-α. Brain Res Bull. 96, 54-61, 2013 (IF:2.9) (Co-first author) Wei XH, Yang T, Wu Q, Xin WJ, Wu JL, Wang YQ, Zang Y, Wang J, Li YY, Liu XG. Peri-sciatic administration of recombinant rat IL-1beta induces mechanical allodynia by activation of src-family kinases in spinal microglia in rats. Exp Neurol. 234:389-397, 2012. (IF:4.1)