在中山大学生命科学学院，于2006本科毕业，2011年获得博士学位

2011年至2015年在美国密歇根大学张建之教授实验室，从事博士后研究工作

目前以第一作者或通讯作者的身份发表具有高影响力的学术论文10余篇，分别刊登在Science (IF:41.1)、Nat Genet (IF:27.1) 、Genome Biology (IF:13.2)、Mol. Biol. Evol. (三篇，IF:10.2)、Genome Res (IF:10.1)、PNAS (IF:9.5)、Cell Systems (IF:9.0)等杂志。学术论著：
19. Yang JR# and Chen X#. Dosage sensitivity of X-linked genes in human embryonic single cells. BMC genomics. 2019 Jan. 14; 20(1): 42.

18. Duan C*, Huan Q*, Chen X*, Wu S, Carey LB, He X and Qian W. Reduced intrinsic DNA curvature leads to increased mutation rate. Genome Biology. 2018 Sep.14; 19(1):132. (*Co-first authors)

17. Chen X, Zhang J. The X to autosome expression ratio in haploid and diploid human embryonic stem cells. Mol. Biol. Evol. 2016 Sep; 33:3104-3107.

16. Chen X, Zhang J. The genomic landscape of position effects on protein expression level and noise in yeast. Cell Syst. 2016 May; 2:347-354

15. Chen X, Yang JR, Zhang J. Nascent RNA folding mitigates transcription associated mutagenesis. Genome Res. 2015 Oct; 26:50-59

14. Chen X, Zhang J. No X-chromosome dosage compensation in human proteomes. Mol. Biol. Evol. 2015 Feb; 32: 1456-60

13. Chen X, Zhang J. Mutation accumulation experiment supports elevated mutation rates at highly transcribed sites. (Letter to Editor) PNAS. 2014 Sep; 111: E4062

12. Yang JR, Chen X, Zhang J. Codon-by-codon modulation of translational speed and accuracy via mRNA folding. PLoS Biol. 2014 Jul; 12: e1001910

11. Chen X, Zhang J. Why Are Genes Encoded on the Lagging Strand of the Bacterial Genome? Genome Biol. Evol. 2013 Nov; 5:2436-9

10. Chen X, Zhang J. No Gene-Specific Optimization of Mutation Rate in Escherichia coli. Mol. Biol. Evol. 2013 Mar; 30:1559-62

9. Park C, Chen X, Yang JR, Zhang J. Differential requirements for mRNA folding partially explain why highly expressed proteins evolve slowly. PNAS. 2013 Feb; 110 (8): 678-86

8. Chen X, Zhang J. The ortholog conjecture is untestable by the current Gene Ontology but is supported by RNA sequencing data. PLOS Comput Biol. 2012 Nov; 8 (11): e1002784

7. Chen X, Chen Z, Chen H, Su Z, Yang J, Shi S, He X. Nucleosomes suppress spontaneous mutations base-specifically in eukaryotes. Science. 2012 Mar; 335(6073):1235-8.

6. He X, Chen X, Xiong Y, Chen Z, Wang X, Shi S, Wang X, Zhang J. He et al. reply. Nat Genet. 2011 Nov; 43(12): 1171-2

5. Yang G, Zhou R, Tang T, Chen X, Ouyang J, He L, Li W, Chen S, Guo M, Li X, Zhong C, Shi S. Gene expression profiles in response to salt stress in Hibiscus tiliaceus. Plant Mol Biol Rep. 2011 Sep; 29 (3):609-17

4. Yang G, Chen X, Tang T, Zhou R, Chen S, Li W, Ouyang J , He L, Shi S. Comparative genomics of two ecologically differential populations of Hibiscus tiliaceus under salt stress. Funct Plant Biol. 2011 Mar; 38(3) 199-208

3. Xiong Y*, Chen X*, Chen Z, Wang X, Shi S, Wang X, Zhang J, He X. RNA sequencing shows no dosage compensation of the active X-chromosome. Nat Genet. 2010 Dec; 42(12):1043-7 (*Co-first authors)

2. Chen X, Shi S, He X. Evidence for gene length as a determinant of gene coexpression in protein complexes. Genetics. 2009 Oct; 183(2):751-4

1. Zhou R, Zeng K, Wu W, Chen X, Yang Z, Shi S, Wu CI. Population genetics of speciation in nonmodel organisms: I. Ancestral polymorphism in mangroves. Mol. Biol. Evol. 2007 Dec; 24(12):2746-54