2005年毕业于中科院微生物研究所，获微生物学博士学位

2005-2006年在中科院生物物理研究所任助理研究员 2006-2010年期间在美国西雅图生物医学研究所接受博士后训练

代表性论文：

Guo X, Carnes J, Ernst NL, Winkler M, Stuart KD. KREPB6, KREPB7, and KREPB8 are important for editing endonuclease function in Trypanosoma brucei.RNA.2012,18(2):308-20.

Sun L, Lv F, Guo X, Gao G. Glycogen synthase kinase 3-beta modulates the antiviral activity of ZAP. J Biol Chem. 2012 Apr 18

Guo X, Ernst N, Carnes J and Stuart K. The Zinc-Fingers of KREPA3 Are Essential for the Complete Editing of Mitochondrial mRNAs in Trypanosoma brucei. PLoS ONE. 2010; 5(1): e8913

Guo X, Ernst N and Stuart K. The KREPA3 zinc finger motifs and OB-fold domain are essential for RNA editing and survival of Trypanosoma brucei. Mol Cell Biol. 2008; 28: 6939-6953.

Chen G, Guo X, Lv F, Xu Y and Gao G. p72 DEAD box RNA helicase is required for optimal function of the zinc-finger antiviral protein. Proc Natl Acad Sci USA. 2008; 105: 4352-4357.

Guo X, Ma J, Sun J and Gao G. The zinc-finger antiviral protein recruits the RNA processing exosome to degrade the target mRNA. Proc Natl Acad Sci USA. 2007; 104: 151-156.

Guo G, MacDonald M, Goff S and Gao G. ZAP directly binds to specific viral mRNAs through the CCCH Zinc Finger Motifs. Journal of Virology. 2004; 78: 12781-12787.

Gao G, Guo X, and Goff S. Inhibition of retroviral RNA production by ZAP, a CCCH-type zinc finger protein. Science. 2002; 297:1703-1706.