博士毕业于四川大学

2009年3月-2011年12月在美国匹兹堡大学医学院感染性疾病系从事博后研究

作为课题负责人主持包括国家自然科学基金重点项目、优青项目、面上项目，广东省自然科学基金杰青项目、面上项目，广州市科技计划珠江新星项目等10余项；作为课题核心骨干参与包括国家传染病重大专项、国家重点研发计划等基金6项。国家自然科学基金重点项目，81830103，质粒介导多粘菌素耐药新机制MCR-1的传播和进化及抑制剂研究，2019/01 -2022/12，主持 国家自然科学基金优秀青年科学基金，81722030，临床细菌耐药与感染，2018/01 -2020/12，主持 广东省自然科学基金杰出青年基金，2017A030306012，质粒介导多粘菌素耐药新机制mcr-1及其传播风险因素研究，2017/01 -2021/12年，主持 “广东特支计划”百千万工程青年拔尖人才，2016，细菌耐药性，主持 国家重大科技专项传染病专项“十三五”计划课题，结核病新型诊断产品研发及其产业化，2017/10-2020/12，参与（核心骨干） 高校基本科研业务费青年教师重点培育项目，16ykzd09，耐碳青霉稀类药物“超级细菌”的耐药传播分子机制及临床治疗，2016/01-2018/12，主持 国家自然科学基金项目，81471988，新型超广谱β-内酰胺酶PME耐药传播分子机制，2015/01-2018/12，主持 国家重点研发计划，2016YFC1200100，输入性传染病的输入机制与播散规律，2016/07-2018/12，参与（核心骨干） 广东省科技发展专项，2016A020219002，动物和人源产碳青霉烯酶超级细菌的流行病学和传播机制比较研究，2016/01-2018/12，主持 广州市珠江新星专项，2014J2200038，广东产新型超广谱β-内酰胺酶PME耐药传播分子机制及风险，2014/01-2016/12，主持 广东省自然科学基金项目，S2013010015810，广东PME酶学功能及耐药传播分子机制，2014/10~2016/10，主持 国家重大科技专项传染病专项“十二五”计划课题，2013ZX10003001，结核病新型诊断产品研发及其产业化，2013/01-2015/12，参与（核心骨干） 广东省海洋经济创新发展区域示范专项项目，GDHY2012-01-001，海洋生物天然产物化合物库，2012/12-2015/12，参与 国家自然科学基金项目，81201325，产CTX-M-15多重耐药E.coli ST131耐药传播分子机制研究，2013/01-2015/1，主持 广东省自然科学基金项目，S2012040006856，广东地区产CTX-M-15多重耐药E.coli ST131耐药传播分子机制研究，2012/10-2014/12，主持

先后在Lancet Infectious Diseases，Clinical Infectious Diseases等本领域国际顶尖和主流期刊上发表SCI论文40篇，通讯/第一27篇，参编专著2部 Shen C, Feng S, Chen H, Dai M, Paterson DL, Zheng X, Wu X, Zhong LL, Liu Y, Xia Y, Ma R, Huang X, Tian GB*. Transmission of mcr-1-producing multidrug-resistant enterobacteriaceae in public transportation in Guangzhou, China. Clinical Infectious Diseases. 2018 Nov 13;67(suppl_2):S217-S224.（通讯作者，中科院一区，影响因子9.117） Xu Y, Zhong LL, Srinivas S, Sun J, Huang M, Paterson DL, Lei S, Lin J, Li X, Tang Z, Feng S, Shen C, Tian GB*, Feng Y. Spread of MCR-3 Colistin Resistance in China: An Epidemiological, Genomic and Mechanistic Study. EBioMedicine. 2018,34:139-157.（共同通讯作者，影响因子6.183） Lan-Lan Zhong*, Hang TT Phan*, Cong Shen , Karina Doris-Vihta , Anna E Sheppard , Xi Huang, Kun-Jiao Zeng, Hong-Yu Li, Xue-Fei Zhang, Sandip Patil , Derrick W Crook , A Sarah Walker, Yong Xing, Jia-lin Lin, Lian-Qiang Feng, Yohei Doi, Yong Xia, Nicole Stoesser#, Guo-Bao Tian#. High rates of human fecal carriage of mcr-1-positive multi-drug resistant Enterobacteriaceae isolates emerge in China in association with successful plasmid families. Clinical Infectious Diseases. 2018 Feb 10;66(5):676-685.（共同通讯作者，中科院一区，影响因子9.117） Siyuan Feng*, Cong Shen*, Hongtao Chen, Xiaobin Zheng, Yong Xia, Lan-Lan Zhong, Xi Huang, Xinwei Wu#, Guo-Bao Tian#. Co-production of MCR-1 and NDM-5 in Escherichia coli isolated from a Colonization Case of Inpatient. Infection and Drug Resistance. 2018 Aug 14;11:1157-1161. doi: 10.2147/IDR.S171164. eCollection 2018（共同通讯作者，中科院三区，影响因子3.779） Lan-Lan Zhong, Nicole Stoesser, Yohei Doi, Cong Shen, Xi Huang, Guo-Bao Tian#. Carriage of β-lactamase-producing Enterobacteriaceae by Chinese travellers. Lancet Infectious Diseases，2017;17(2):138-139.（通讯作者，中科院一区，影响因子25.148） Yang Wang*, Guo-Bao Tian*, Rong Zhang*, Yingbo Shen*, Jonathan M. Tyrrell, Xi Huang, Hongwei Zhou, Lei Lei, Hong-Yu Li, Yohei Doi, Ying Fang, Hongwei Ren, Lan-Lan Zhong, Zhangqi Shen, Kun-Jiao Zeng, Shaolin Wang, Jian-Hua Liu, Congming Wu, Timothy R. Walsh#, Jianzhong Shen#. Prevalence, risk factors, outcomes, and molecular epidemiology of mcr-1-positive Enterobacteriaceae in patients and healthy adults from China: an epidemiological and clinical study. Lancet Infectious Diseases. 2017;17 (4):390-399.（共同第一作者，中科院一区，影响因子25.148） Guo-Bao Tian, Yohei Doi, Jianzhong Shen, Timothy R. Walsh, Yang Wang, Rong Zhang, Xi Huang#. An outbreak of MCR-1-producing Klebsiella pneumoniae in China. Lancet Infectious Diseases. 2017; 17 (6):577.（通讯作者，中科院一区，影响因子25.148） Xue-Fei Zhang, Yohei Doi, Xi Huang, Hong-Yu Li, Lan-Lan Zhong, Kun-Jiao Zeng, Yan-Fen Zhang, Sandip Patil, Guo-Bao Tian#. Possible Transmission of mcr-1-Harboring Escherichia coli between Companion Animals and Human. Emerging Infectious Diseases. 2016; 22(9):1679-81. (通讯作者，中科院一区，影响因子8.222) Lan-Lan Zhong, Yan-Fen Zhang, Yohei Doi, Xi Huang, Xue-Fei Zhang, Kun-Jiao Zeng, Cong She, Sandip Patil, Yong Xing, Yutian Zou, Guo-Bao Tian#. Co-production of MCR-1 and NDM-1 by colistin-resistant Escherichia coli isolated from a healthy individual. Antimicrobial Agents and Chemotherapy. 2016;61(1). pii: e01962-16. (通讯作者，中科院二区，影响因子4.302) Kun-jiao Zeng, Yohei Doi, Sandip Patil, Xi Huang, Guo-Bao Tian#. Emergence of the Plasmid-Mediated mcr-1 Gene in Colistin-Resistant Enterobacter aerogenes and Enterobacter cloacae. Antimicrobial Agents and Chemotherapy. 2016;60(6):3862-3. (通讯作者，中科院二区，影响因子4.302) Guo-Bao Tian, Yi-Qi Jiang, Ying-Min Huang,Yun Qin, Lian-Qiang Feng, Xue-Fei Zhang, Hong-Yu Li, Lan-Lan Zhong, Kun-Jiao Zeng, Sandip Patil, Yong Xing, Xi Huang#. Characterization of CTX-M-140, a Variant of CTX-M-14 Extended-Spectrum β-Lactamase (ESBL) with Decreased Cephalosporin Hydrolytic Activity, from Cephalosporin-Resistant Proteus mirabilis. Antimicrobial Agents and Chemotherapy. 2016;60(10):6121-6. (通讯作者，中科院二区，影响因子4.302) Ying-Min Huang, Lan-lan Zhong, Xue-Fei Zhang, Hang-tong Hu, Yu-qi Li, Xiao-rong Yang, Lian-Qiang Feng, Xi Huang, Guo-Bao Tian#. NDM-1-Producing Citrobacter freundii, Escherichia coli, and Acinetobacter baumannii Identified from a Single Patient in China. Antimicrobial Agents and Chemotherapy. 2015;59(8):5073-7. (通讯作者，中科院二区，影响因子4.302) Guo-Bao Tian*, Ying-Min Huang*, Zhi-Li Fang, Yun Qing, Xue-Fei Zhang, Xi Huang#. CTX-M-137, a Hybrid of CTX-M-14-Like and CTX-M-15-Like β-Lactamases Identified in an Escherichia coli Clinical Isolate. Journal of Antimicrobial Chemotherapy. 2014;69(8):2081-5. (共同第一作者，中科院二区，影响因子5.338) Yun Qing, Kai-Yuan Cao, Zhi-Li Fang, Ying-Min Huang, Xue-Fei Zhang, Guo-Bao Tian#, Xi Huang#. Outbreak of PER-1 and Diversity of β-Lactamases among Ceftazidime-Resistant Pseudomonas aeruginosa Clinical Isolates in China. Journal of Medical Microbiology. 2014;63(Pt 3):386-92. (共同通讯作者，中科院三区，影响因子2.159) Zhi-liFang, Li-yan Zhang, Ying-min Huang, Yun Qing, Kai-yuan Cao, Guo-bao Tian#, Xi Huang#. OprD mutations and inactivation in imipenem-resistant Pseudomonas aeruginosa isolates from China. Infection, Genetics and Evolution. 2014; 21:124-8. (共同通讯作者，中科院三区，影响因子2.885) Guo-Bao Tian, Hong-Ning Wang#, An-Yun Zhang, Yi Zhang, Wen-Qiao Fan, Chang-Wen Xu, Bo Zeng, Zhong-Bin Guan, Li-Kou Zou. Detection of clinically important β-lactamases in commensal Escherichia coli of human and swine origin in western China. Journal of Medical Microbiology. 2012; 61(Pt 2):233-8. (第一作者，中科院三区，影响因子2.159) Guo-Bao Tian, Jennifer M. Adams-Haduch, Tatiana Bogdanovich, Anthony W. Pasculle, John P. Quinn, Hong-Ning Wang, Yohei Doi#. Identification of Diverse OXA-40-Group Carbapenemases Including a Novel Variant, OXA-160, from Acinetobacter baumannii in Pennsylvania. Antimicrobial Agents and Chemotherapy. 2010; 55:429-32. (第一作者，中科院二区，影响因子4.302) Guo-Bao Tian, Jennifer M. Adams-Haduch, Tatiana Bogdanovich, Hong-Ning Wang, Yohei Doi#. PME-1, an Extended-Spectrum β-lactamase Identified in Pseudomonas aeruginosa. Antimicrobial Agents and Chemotherapy. 2011; 55: 2710-2713. (第一作者，中科院二区，影响因子4.302) Guo-Bao Tian, Jennifer M. Adams-Haduch, Tatiana Bogdanovich, Yohei Doi#. Sequence Type ST405 Escherichia coli Isolate Producing QepA1, CTX-M-15, and RmtB from Detroit, Michigan. Antimicrobial Agents and Chemotherapy. 2011; 55: 3966-3967. (第一作者，中科院二区，影响因子4.302) Guo-Bao Tian, Jennifer M. Adams-Haduch, Tatiana Bogdanovich, Hong-Ning Wang, Yohei Doi#. Extended-Spectrum AmpC in Acinetobacter baumannii ADC-56 Confers Resistance to cefepime. Antimicrobial Agents and Chemotherapy. 2011; 55: 4922-4925. (第一作者，中科院二区，影响因子4.302) Guo-Bao Tian, Jemelyn Garcia, Jennifer M. Adams-Haduch, Jennifer P. Evangelista, Raul V. Destura, Hong-Ning Wang, Yohei Doi#. CTX-M as the predominant extended-spectrum β-Lactamase among Enterobacteriaceae in Manila, Philippines. Journal of Antimicrobial Chemotherapy. 2010; 65: 584-6. (第一作者，中科院二区，影响因子5.338) Guo-Bao Tian, Jennifer M. Adams-Haduch, Zubair A. Qureshi, Hong-Ning Wang, Yohei Doi#. CTX-M-35 Extended-Spectrum β-Lactamase Conferring Ceftazidime Resistance in Citrobacter koserii. International Journal of Antimicrobial Agents. 2010; 35: 412-3. (第一作者，中科院二区，影响因子4.307) Guo-Bao Tian, Hong-Ning Wang, Li-Kou Zou, Jun-Ni Tang, Ying-Wang Zhao, Man-Yu Ye, Jing-Yuan Tang, Yi Zhang, An-Yun Zhang, Xin Yang, Chang-Wen Xu, Yue-Jun Fu. Detection of CTX-M-15, CTX-M-22, and SHV-2 Extended-Spectrum bata-Lactamases (ESBLs) in Escherichia coli Fecal-Sample Isolates from Pig Farms in China. Foodborne Pathogens and Disease. 2009; 6:297-304. (第一作者，中科院四区，影响因子2.120) Yi-Yun Liu, Yang Wang, Timothy R Walsh, Ling-Xian Yi, Rong Zhang, James Spencer, Yohei Doi, Guo-bao Tian, Baolei Dong, Xianhui Huang, Lin-Feng Yu, Danxia Gu, Hongwei Ren, Xiaojie Chen, Luchao Lv, Dandan He, Hongwei Zhou, Zisen Liang, Jian-Hua Liu#, Jianzhong Shen#. Emergence of plasmid-mediated colistin resistance mechanism MCR-1 in animals and human beings in China: a microbiological and molecular biological study. Lancet Infectious Diseases. 2016; 16(2):161-8. doi: 10.1016/S1473-3099(15)00424-7. (合作作者，中科院一区，影响因子25.148) Rongsui Gao,Yongfei Hu,Zhencui Li,Jian Sun,Qingjing Wang,Jingxia Lin,Huiyan Ye,Fei Liu,Swaminath Srinivas, Defeng Li,Baoli Zhu,Ya-Hong Liu, Guo-Bao Tian, Youjun Feng#. Dissemination and Mechanism for the MCR-1 Colistin Resistance. PLOS Pathogens. 2016 Nov 28;12(11):e1005957. (合作作者，中科院一区，影响因子6.608) Yan-Xiu Chen, Meng-Yang Xu, Hou-Jin Li, Kun-Jiao Zeng,Wen-Zhe Ma, Guo-Bao Tian, Jun Xu, De-Po Yang, Wen-Jian Lan#. Diverse Secondary Metabolites from the Marine-Derived Fungus Dichotomomyces cejpii F31-1. Marine Drugs. 2017 Nov 1;15(11). pii: E339. doi: 10.3390/md15110339. (合作作者，中科院三区，影响因子3.503) Tatiana Bogdanovich, Jennifer M. Adams-Haduch, Guo-Bao Tian, Hong M. Nguyen, Eun J. Kwak, Carlene A. Muto, Yohei Doi#. Colistin Resistant Klebsiella pneumoniae Carbapenemase (KPC) Producing Klebsiella pneumoniae Belonging to the International Epidemic Clone ST258. Clinical Infectious Diseases. 2011; 53: 373-376. (合作作者，中科院一区，影响因子8.2159） Hanna E. Sidjabat, David L. Paterson, Jennifer M. Adams-Haduch, Lindsay Ewan, Anthony W. Pasculle, Carlene A. Muto, Guo-Bao Tian, Yohei Doi#. Molecular Epidemiology of CTX-M-Producing Escherichia coli Isolates at a Tertiary Medical Center in Western Pennsylvania. Antimicrobial Agents and Chemotherapy. 2009; 53: 4733-9. (合作作者，中科院二区，影响因子4.302) Rebecca I. Waltner-Toews, David L. Paterson, Zubair A. Qureshi, Hanna E. Sidjabat, Jennifer M. Adams-Haduch, Kathleen A. Shutt, Mark Jones, Guo-Bao Tian, Anthony W. Pasculle, Yohei Doi#. Clinical Characteristics of Bloodstream Infections Due to Ampicillin/Sulbactam-Resistant, Non-ESBL-Producing Escherichia coli and the Role of TEM-1 Hyperproduction. Antimicrobial Agents and Chemotherapy. 2011; 55: 495-501. (合作作者，中科院二区，影响因子4.302) Jennifer M. Adams-Haduch, Ezenwa O. Onuoha, Tatiana Bodganovich, Guo-Bao Tian, Jonas Marschall, Carl Urban, Brad Spellberg, Diane Rhee, Diane Halstead, Anthony W. Pasculle, Yohei Doi#. Molecular Epidemiology of Carbapenem-Resistant Acinetobacter baumannii in the United States. Journal of Clinical Microbiology. 2011;49(11):3849-54. (合作作者，中科院二区，影响因子3.712)
教材

全国高等教育医学数字化规划教材《医学微生物学》，人民军医出版社，编委(编写内容：第七章细菌耐药性) “十三五”高等教育医药院校规划教材《医学微生物学》，郑州大学出版社，副主编（主编杨帆、魏纪东）

以第一发明人申请专利8项（授权2项）