教育背景
2005年毕业于武汉大学生命科学学院获得理学学士学位。2010年毕业于中国科学院昆明动物研究所获得遗传学博士学位(师从宿兵研究员)。
工作经历
2010年至2016年分别在美国爱荷华大学(2010~2012)和加州大学洛杉矶分校(2013~2016)Yi Xing教授实验室从事生物信息学方向博士后研究。
项目课题经历
论文、成果、著作等
目前已经以第一作者或共同第一作者身份在Nature Methods (IF: 25.3)、Cell Stem Cell (IF: 22.4)、Molecular Biology and Evolution (IF: 13.6)、Genome Biology (IF: 11.3)、Human Molecular Genetics (IF: 6.0)等杂志发表论文9篇。学术论著与教材:
* 并列第一作者; # 通讯作者
Zhou C*, Molinie B*, Daneshvar K, Pondick JV, Wang J, Wittenberghe NV, Xing Y, Giallourakis CC#, Mullen AC#. (2017). Genome-Wide Maps of m6A circRNAs Identify Widespread and Cell-Type-Specific Methylation Patterns that Are Distinct from mRNAs. Cell Reports, 20(9), 2262–2276. (IF=8.3)
Wang J, Pan Y, Shen S, Lin L, Xing Y#. (2017). rMATS-DVR: rMATS discovery of Differential Variants in RNA. Bioinformatics 33(14), 2216-2217. (IF=5.8)
Molinie B*, Wang J*, Lim KS, Hillebrand R, Lu ZX, Wittenberghe NV, Howard BD, Daneshvar K, Mullen AC, Dedon P, Xing Y#, Giallourakis CC#. (2016) m6A-LAIC-seq reveals the census and complexity of the m6A epitranscriptome. Nature Methods, 13(8):692-698. (IF=25.3)
Batista PJ*, Molinie B*, Wang J*, Qu K, Zhang J, Li L, Bouley DM, Lujan E, Haddad B, Daneshvar K, Carter AC, Flynn RA, Zhou C, Lim KS, Dedon P, Wernig M, Mullen AC, Xing Y#, Giallourakis CC#, Chang HY# (2014) m6A RNA modification controls cell fate transition in mammalian embryonic stem cells. Cell Stem Cell 15(6): 707–719. (IF=22.4)
Wang J*, Lu ZX*, Tokheim C, Miller SE, Xing Y#. (2015) Species-specific exon loss in human transcriptomes. Molecular Biology and Evolution 32(2): 481-94. (IF=13.6)
Lin L*#, Jiang P*, Park JW*, Wang J*, Lu ZX, Lam MPY, Ping P, Xing Y#. (2016) The contribution of Alu exons to the human proteome.Genome Biology 28;17(1):15 (IF=11.3)
Wang J*, Ma MCJ*, Mennie AK*, Pettus JM, Xu Y, Lin L, Traxler MG, Jakoubek J, Atanur SS, Aitman TJ, Xing Y#, Kwitek AE#. (2015) Systems biology with high-throughput sequencing reveals genetic mechanisms underlying the metabolic syndrome in the Lyon hypertensive rat. Circulation: Cardiovascular Genetics 8(2):316-326. (IF=3.7)
Zhao Y*, Ji S*, Wang J*, Huang J#, Zheng P# (2014) mRNA-Seq and microRNA-Seq whole-transcriptome analyses of rhesus monkey embryonic stem cell neural differentiation revealed the potential regulators of rosette neural stem cells. DNA Research 21(5): 541–554. (IF=5.3)
Li M*, Huang L*, Wang J*, Su B#, Luo X-J# (2016) No association between schizophrenia susceptibility variants and macroscopic structural brain volume variation in healthy subjects. Am J Med Genet B Neuropsychiatr Genet. 171B(2):160-8. (IF=3.4)
Wang J*, Cao X*, Zhang Y, Su B#. (2012) Genome-wide DNA methylation analyses in the brain reveal four differentially methylated regions between humans and non-human primates. BMC evolutionary biology 12(1): 144. (IF=3.4)
Wang J, Li Y, Su B#. (2008) A common SNP of MCPH1 is associated with cranial volume variation in Chinese population. Human Molecular Genetics 17(9): 1329-1335. (IF=6.0)
Li M, Huang L, Li K, Huo Y, Chen C, Wang J, Liu J, Luo Z, Chen C, Dong Q, Yao YG, Su B, Luo XJ#. (2016) Adaptive evolution of interleukin-3 (IL3), a gene associated with brain volume variation in general human populations. Human Genetics. 135(4):377-92. (IF=5.1)
Luo X-J, Li M, Huang L, Nho K, Deng M, ... Wang J, … Su B#. (2012) The Interleukin 3 Gene (IL3) Contributes to Human Brain Volume Variation by Regulating Proliferation and Survival of Neural Progenitors. PLoS ONE 7: e50375. (IF=3.1)
Kim J, Zhao K, Jiang P, Lu ZX, Wang J, Murray JC, Xing Y#. (2012) Transcriptome landscape of the human placenta. BMC genomics 13: 115. (IF=3.9)
Niu AL, Wang YQ, Zhang H, Liao CH, Wang J, Zhang R, Che J, Su B#. (2011) Rapid evolution and copy number variation of primate RHOXF2, an X-linked homeobox gene involved in male reproduction and possibly brain function. BMC evolutionary biology 11: 298. (IF=3.4)
Luo XJ, Diao HB, Wang J, Zhang H, Zhao ZM and Su B#. (2008) Association of haplotypes spanning PDZ-GEF2, LOC728637 and ACSL6 with schizophrenia in Han Chinese. J Med Genet, 45(12), 818-826. (IF=5.7)
Zhou L, Wang J, Yi Q, Wang YZ, Zhu YG and Zhang ZH#. (2007) Quantitative trait loci for seedling vigor in rice under field conditions. Field Crop Res 100: 294-301. (IF=2.9)
专利、著作版权等
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