教育背景
1995年获白求恩医科大学临床医学学士学位(现吉林大学医学部)。1999年在丹麦奥胡斯大学留学,2004年获得奥胡斯大学医学博士学位
工作经历
2004年后在美国美国科罗拉多医学中心从事博士后工作并晋职研究型讲师。2012年2月回国加入中山大学中山医学院工作。
项目课题经历
科研项目研究课题:
国家自然科学面上项目,2019-2022;项目负责人
国家自然基金面上项目,2016-2019;项目负责人。
广东省自然科学基金自由申请项目,2015-2017;项目负责人。
教育部留学回国人员启动基金,2014-2016;项目负责人。
广东省自然科学基金自由申请项目,2013-2015;项目负责人。
中山大学百人计划启动基金,2012-2013;项目负责人。
国家自然基金重点项目,2014-2018;项目参与者。
论文、成果、著作等
发表SCI论文(通讯作者和第一作者):
1.Luo R#, Hu S#, Liu Q, Han M, Wang F, Qiu M, Li S, Li X, Yang T, Fu X, Wang W*, Li C*. Hydrogen Sulfide Upregulates Renal AQP2 Protein Expression and Promotes Urine Concentration. FASEB J. 2019 Jan;33(1):469-483. (IF=5.6)
2.Li S, Qiu M, Kong Y, Zhao X, Choi HJ, Reich M, Bunkelman BH, Liu Q, Hu S, Han M, Xie H, Rosenberg AZ, Keitel V, Kwon TH, Levi M, Li C*, Wang W*. Bile Acid G Protein-Coupled Membrane Receptor TGR5 Modulates Aquaporin 2-Mediated Water Homeostasis. J Am Soc Nephrol. 2018 Nov;29(11):2658-2670. (IF=8.6)
3.Wang F, Liu Q, Luo R, Hu S, Han M, Zhai Y, Wang W, Li C* Combination exposure of melamine and cyanuric acid is associated with polyuria and activation of NLRP3 inflammasome in rats. Am J Physiol Renal Physiol. 2018 Aug 1;315(2):F199-F210. (IF=3.6)
4.Wang F, Zhu S, Fisher LA, Wang W, Oakley GG, Li C*, Peng A*. Protein interactomes of protein phosphatase 2A B55 regulatory subunits reveal B55-mediated regulation of replication protein A under replication stress. Sci Rep. 2018 Feb 8;8(1):2683.
5. Luo R, Kakizoe Y, Wang F, Fan X, Hu S, Yang T, Wang W, Li C*. Deficiency of mPGES-1 exacerbates renal fibrosis and inflammation in mice with unilateral ureteral obstruction. Am J Physiol Renal Physiol, 2017 Jan 1;312(1):F121-F133
6.Wang W, Li C, Yang T*. Protection of Nitro-Fatty Acid against Kidney Diseases. Am J Physiol Renal Physiol. 2016 Mar 1;310(5):F351-63, review.
7. Li C#, Lin Y#, Luo R, Chen S, Wang F, Zheng P, Levi M, Yang T, Wang W*. Intrarenal Renin-Angiotensin System Mediates Fatty Acid-Induced ER Stress in the Kidney. Am J Physiol Renal Physiol. 2016 Mar 1;310(5):F351-63.
8.Wang W#, Luo R#, Lin Y, Wang F, Zheng P, Levi M, Yang T, Li C*. Aliskiren Restores Renal AQP2 Expression during Unilateral Ureteral Obstruction by Inhibiting the Inflammasome. Am J Physiol Renal Physiol, 2015, Apr 15;308(8):F910-22.4.
9. Li C, Wang W, Rivard C, Lanaspa M, Summer S, Schrier RW. Molecular mechanisms of angiotensin II stimulation on aquaporin-2 expression and trafficking. Am J Physiol Renal Physiol. 2011 May;300(5):F1255-61
10. Li C, Wang W, Summer SN, Falk S, Schrier RW. Downregulation of UT-A1/UT-A3 is associated with urinary concentrating defect in glucocorticoid-excess state. J Am Soc Nephrol. 2008 Oct;19(10):1975-81. (IF=8.6)
11. Li C, Wang W, Summer SN, Westfall TD, Brooks DP, Falk S, Schrier RW. Molecular Mechanisms of Antidiuretic Effect of Oxytocin. J Am Soc Nephrol. 2008 Feb;19(2):225-32. (IF=8.6)
12. Li C, Wang W, Norregaard R, Knepper MA, Nielsen S, Frokiaer J. Altered expression of epithelial sodium channel (ENaC) in rats with bilateral or unilateral ureteral obstruction. Am J Physiol Renal Physiol. 2007 Jul;293(1):F333-41.
13. Li C, Wang W, Summer SN, Cadnapaphornchai MA, Falk S, Umenishi F, Schrier RW. Hyperosmolality In Vivo Upregulates Aquaporin 2 Water Channel and Na-K-2Cl Co-Transporter in Brattleboro Rats. J Am Soc Nephrol. 2006 Jun;17(6):1657-64 . (IF=8.6)
14. Li C, Shi Y, Wang W, Sardeli C, Kwon TH, Thomsen K, Jonassen T, Djurhuus JC, Knepper MA, Nielsen S, Frokiaer J. alpha-MSH prevents impairment in renal function and dysregulation of AQPs and Na-K-ATPase in rats with bilateral ureteral obstruction.Am J Physiol Renal Physiol. 2006 Feb;290(2):F384-96.
15.Li C, Klein JD, Wang W, Knepper MA, Nielsen S, Sands JM, Frokiaer J. Altered expression of urea transporters in response to ureteral obstruction. Am J Physiol Renal Physiol. 2004 Jun;286(6):F1154-62
16.Li C, Wang W, Kwon T-H, Knepper MA, Nielsen S, Frokiaer J. Altered expression of major renal Na transporters in rats with bilateral ureteral obstruction and release of obstruction. Am J Physiol Renal Physiol. 2003 Nov;285(5):F889-F901.
17.Li C, Wang W, Knepper MA, Nielsen S, Frokiaer J. Downregulation of renal aquaporins in response to unilateral ureteral obstruction. Am J Physiol Renal Physiol. 2003 May; 284(5): F1066-F1079.
18.Li C, Wang W, Kwon TH, Knepper MA, Nielsen S, Frokiaer J. Altered expression of major renal Na transporters in rats with unilateral ureteral obstruction. Am J Physiol Renal Physiol. 2003 Jan;284(1):F155-66.
19.Li C, Wang W, Kwon TH, Isikay L, Wen JG, Marples D, Djurhuus JC, Stockwell A, Knepper MA, Nielsen S, Frokiaer J. Downregulation of AQP1, -2, and -3 after ureteral obstruction is associated with a long-term urine-concentrating defect. Am J Physiol Renal Physiol. 2001 Jul;281(1):F163-71.
参编英文书籍(章节):
1. Li C and Wang W, Molecular Biology of Aquaporins. In Advances in Experimental Medicine and Biology 969 Aquaporins, editor, Yang B. ©Springer Science+Business Media B.V. 2017. ISBN 978-94-024-1055-6.
2. Li C and Wang W, Urea transport mediated by water channel protein aquaporins. Subcell Biochem. 2014;73:227-65. ©Springer Science+Business Media Dordrecht 2014. ISBN 978-94-017-9342-1.
参编中文教材(章节):
1.全国高等学校教材: 五年制临床医学专业教材,第九版《生理学》,编委,人民卫生出版社,2018。
2.全国高等学校五年制临床医学专业第九版规划教材配套教材,《生理学学习指导与习题集》,编委,人民卫生出版社,2018。
3.全国高等教育五年制临床医学专业教材精编速览,《病理生理学》,副主编,中国医药科学出版社,2018。
4.全国高等教育五年制临床医学专业教材精编习题集,《病理生理学》,编委,中国医药科学出版社,2018。
专利、著作版权等
声明:本站专家信息来源于各高校官网。