2007年于武汉大学生命科学学院获得学士学位；2012年于中科院上海生命科学研究院健康科学研究所获得细胞生物学博士学位

于2012年起在美国加州大学旧金山分校戴维•格拉斯通研究所（J. David Gladstone Institutes）从事博士后研究

获得基金:

1. 第十三批千人计划“青年项目” 主持

2017-2020 中组部

2. 国家重点研发计划“干细胞及转化研究”重点专项青年项目 首席科学家

2018-2023 科技部

3. 国家重点研发计划“蛋白质机器与生命过程调控”重点专项 学术骨干

2018-2023 科技部

4. 国家自然科学基金“面上项目” 主持

2018-2021 国家自然科学基金委

5. 广东省“珠江人才计划”引进创新创业团队 核心成员

2017-2021 广东省科学技术厅

6. 中山大学青年教师重点培育项目 主持

2018-2020 中山大学

7. Research Scholar Program Award (TG2-01160) 主持

2014–2015 California Institute for Regenerative Medicine (CIRM)

在 Science (IF: 41.1)、Nature (IF: 41.6)、Cell Stem Cell (IF: 23.3)、Nature Cell Biology (IF: 19.1)、Cell Research (IF: 15.4)、Cell Reports (IF: 8.0)、Stem Cells (IF: 5.6) 等著名期刊上发表SCI学术论文16篇，平均 IF：16.6/篇。其中以第一/通讯作者发表学术论文/论著8篇，包括Science、Cell Stem Cell、Cell Research (3篇)、Stem Cells、ACS Chem Bio.以及 Methods Mol Bio.等，学术论文平均 IF：19.4/篇。Peer-Reviewed Research Articles



Han Z, Yu Y, Xu J, Bao Z, Xu Z, Hu J, Yu M, Bamba D, Ma W, Ding F, Zhang L, Jin M, Yan G, Huang Q, Wang X, Hua B, Yang F, Li Y, Lei L, Cao N*, Pan Z*, Cai B*. Iron Homeostasis Determines Fate of Human Pluripotent Stem Cells Via Glycerophospholipids-Epigenetic Circuit. Stem Cells. 2018 Dec 31 (IF: 5.6) Chen ZY, Chen F, Cao N, Zhou ZW, Yang HT*. miR-142-3p contributes to early cardiac fate decision of embryonic stem cells. Stem Cells Int. 2017;2017:1769298 (IF: 3.5) Xu T, Stewart K, Wang X, Liu K, Xie Min, Ryu JK, Li K, Ma T, Wang H, Ni L, Zhu S, Cao N, Don W, Zhang Y, Akassoglou K, Dong C, Driggers EM and Ding S*. Metabolic control of TH17 and induced Treg cell balance by an epigenetic mechanism. Nature 2017 Aug 10;548(7666):228-233 (IF: 41.6). Cao N, Huang Y, Zheng J, Spencer CI, Zhang Y, Fu JD, Nie B, Xie M, Zhang M, Wang H, Ma T, Xu T, Shi G, Srivastava D, Ding S*. Conversion of human fibroblasts into functional cardiomyocytes by small molecules. Science 2016 Jun 3;352(6290):1216-20 (IF: 41.1). Zhang Y#, Cao N#, Huang Y, Spencer CI, Fu JD, Yu C, Liu K, Nie B, Xu T, Li K, Xu S, Bruneau BG, Srivastava D, Ding S*. Expandable cardiovascular progenitor cells reprogrammed from fibroblasts. Cell Stem Cell 2016 Mar 3;18(3):368-81 (IF: 23.3) (Featured article, highlighted by Yamashita JK. Expanding reprogramming to cardiovascular progenitors. Cell Stem Cell 2016 Mar 3;18(3):299-301. #equally contributing authors). Zhang M, Lin YH, Sun YJ, Zhu S, Zheng J, Liu K, Cao N, Li K, Huang Y, Ding S*. Pharmacological reprogramming of fibroblasts into neural stem cells by signaling-directed transcriptional activation. Cell Stem Cell 2016 May 5;18(5):653-67 (IF: 23.3). Ma T, Li J, Xu Y, Yu C, Xu T, Wang H, Liu K, Cao N, Nie BM, Zhu SY, Xu S, Li K, Wei WG, Wu Y, Guan KL, Ding S*. Atg5-independent autophagy regulates mitochondrial clearance and is essential for iPSC reprogramming. Nature Cell Biology 2015 Nov;17(11):1379-87 (IF: 19.1). Cao N, Liang H, Yang HT*. Generation, expansion, and differentiation of cardiovascular progenitor cells from human pluripotent stem cells. Methods in Molecular Biology 2015; 1212:113-25. Wang H, Cao N, Spencer CI, Nie B, Ma T, Xu T, Zhang Y, Wang X, Srivastava D, Ding S*. Small molecules enable cardiac reprogramming of mouse fibroblasts with a single factor, Oct4. Cell Reports 2014 Mar 13;6(5):951-60 (IF: 8.0). Cao N#, Liang H#, Huang J, Wang J, Chen Y, Chen Z, Yang HT*. Highly efficient induction and long-term maintenance of multipotent cardiovascular progenitors from human pluripotent stem cells under defined conditions. Cell Research 2013 Sep;23(9):1119-32 (IF: 15.4; #equally contributing authors). Cao N, Liu Z, Chen Z, Wang J, Chen T, Zhao X, Ma Y, Qin L, Kang J, Wei B, Wang L, Jin Y, Yang HT*. Ascorbic acid enhances the cardiac differentiation of induced pluripotent stem cells through promoting the proliferation of cardiac progenitor cells. Cell Research 2012 Jan;22(1):219-36 (IF: 15.4). Wang J, Cao N, Yuan M, Cui HJ, Tang Y, Qin LJ, Huang XF, Shen N, Yang HT*. MicroRNA-125b/Lin28 pathway contributes to the mesendodermal fate decision of embryonic stem cells. Stem Cells Dev. 2012 Jun 10;21(9):1524-37 (IF: 3.6). Cao N#, Liao J#, Liu ZM, Zhu WM, Wang J, Liu LJ, Yu LL, Xu P, Cui C, Xiao L, Yang HT*. In vitro differentiation of rat embryonic stem cells into functional cardiomyocytes. Cell Research 2011 Sep;21(9):1316-31 (IF: 15.4; #equally contributing authors). Liang J, Wang YJ, Tang Y, Cao N, Wang J, Yang HT*. Type 3 inositol 1,4,5-trisphosphate receptor negatively regulates apoptosis during mouse embryonic stem cell differentiation. Cell Death & Diff. 2010 Jul;17(7):1141-54 (IF: 8.0).
Review Articles

Tang S, Xie M, Cao N, Ding S*. Patient-specific induced pluripotent stem cells for disease modeling and phenotypic drug discovery. J Med Chem. 2016 Jan 14;59(1):2-15 (IF: 6.3). Xie M#, Cao N#, Ding S*. Small molecules for cell reprogramming and heart repair: progress and perspective. ACS Chem Biol. 2014 Jan 17;9(1):34-44 (IF: 5.1; *equally contributing authors). Feng YL, Wang YH, Cao N, Yang HT*, Wang YG*. Progenitor/stem cell transplantation for repair of myocardial infarction: Hype or hope? Ann Palliat Med. 2012;1(1):65-77. Liang H, Wang J, Cao N, Huang JJ, Yang HT*. Differentiation of embryonic stem cells and induced pluripotent stem cells into cardiomyocytes: Progresses and perspectives. Chin Bull Life Sci. 2009;21(5):663-668.

申请/获授权国际专利 2项、美国专利2项、中国专利1项。Yu Zhang, Nan Cao, Sheng Ding. US2019/0017029. Yu Zhang, Nan Cao, Sheng Ding. PCT/US2017/019295. Nan Cao, Sheng Ding. PCT/US2014/055083. Nan Cao, Sheng Ding. US2016/0186141. 杨黄恬，曹楠，梁贺。CN201210491649.