教育背景
1992.10—1995.4:德国海德堡大学第二生理研究所,获博士学位
1985.9—1988.8:白求恩医科大学生理教研室,获硕士学位
1978.3—1982.12:延边医学院医学系,获学士学位
工作经历
1999年6月始 :中山医科大学生理教研室主任,教授
1997.5—1999.5:德国基尔大学生理研究所,博士后
1995.5—1997.4:德国海德堡大学第二生理研究所,博士后
1988.9—1992.9:华北煤炭医学院生理教研室,讲师
1983.1—1985.8:内蒙古民族医学院生理教研室,助教
项目课题经历
论文、成果、著作等
在SCI收录的期刊上发表二十余篇研究论文,被引用近500次 发表论文:
1. BDNF induces late-phase LTP of C-fiber evoked field potentials in rat spinal dorsal horn
所有作者: 发表杂志: 发表年份:2008
2. Peri-sciatic administration of recombinant rat TNF-α induces mechanical allodynia via up-regulation of TNF-α in dorsal root ganglia and in spinal dorsal horn: the role of NF-kappa B pathway. Experimental Neurology, 205:471-484。
所有作者: 发表杂志: 发表年份:2007
3. p38 activation in uninjured primary afferent neurons and in spinal microglia contributes to the development of neuropathic pain induced by selective motor fiber injury. Experimental Neurology, 204 (1): 355-365.
所有作者: 发表杂志: 发表年份:2007
4. Tumor necrosis factor-alpha induces long-term potentiation of C-fiber evoked field potentials in spinal dorsal horn in rats with nerve injury: The role of NF-kappa B, JNK and p38 MAPK. Neurophamarcology, 52:708-715.
所有作者: 发表杂志: 发表年份:2007
5. NMDA receptor channels are involved in the expression of long-term potentiation of C-fiber evoked field potentials in rat spinal dorsal horn. Progress in biochemistry and biophysics, 33 (12): 1183-1189.
所有作者: 发表杂志: 发表年份:2006
6. Clonidine depresses LTP of C-fiber evoked field potentials in spinal dorsal horn via NO-cGMP pathway. Brain Res, 1118 (1): 58-65.
所有作者: 发表杂志: 发表年份:2006
7. Inhibition of protein tyrosine kinases attenuated Aβ-fiber-evoked synaptic transmission in spinal dorsal horn of rats with sciatic nerve transection. J Pharmacol Sci, 102 (1): 64-71.
所有作者: 发表杂志: 发表年份:2006
8. The role of phosphorylation of ERK in induction and maintenance of LTP of the C-fiber evoked field potentials in spinal dorsal horn. J Neurosci Res, 84(5): 934-43.
所有作者: 发表杂志: 发表年份:2006
9. The role of tumour necrosis factor-alpha in the neuropathic pain produced by lumbar 5 ventral root transection in rat. Pain, 123:306-321.
所有作者: 发表杂志: 发表年份:2006
10. Diazepam inhibits the induction and maintenance of LTP of C-fiber evoked field potentials in spinal dorsal horn of rats. Neuropharmacology, 50(2): 238-244.
所有作者: 发表杂志: 发表年份:2006
11. Activation of Spinal D1/D5 Receptors Induces Late Phase LTP of C-fiber Evoked Field Potentials in Rat Spinal Dorsal Horn. J Neurophysiol, 94 (2):961-967.
所有作者: 发表杂志: 发表年份:2005
12. PKC在成年大鼠脊髓背角C-纤维诱发电位长时程增强的诱导和维持中的作用。中国病理生理学杂志,21(2);252-255。
所有作者: 发表杂志: 发表年份:2005
13. Acute nerve injury induces LTP of C-fiber evoked field potentials in spinal dorsal horn of intact rat. Sheng Li Xue Bao,56:591-596.
所有作者: 发表杂志: 发表年份:2004
14. KN-93抑制脊髓背角C 纤维诱发场电位长时程增强的诱导和早期表达。中山大学学报,24(4):109-113。
所有作者: 发表杂志: 发表年份:2003
15. 刺激Aδ纤维可抑制背角C-纤维诱发电位长时程增强.中国临床康复,7(10):1510-1512。(
所有作者: 发表杂志: 发表年份:2003
16. 磷酸化CaMKII 在脊髓背角C-纤维诱发LTP诱导和维持中的作用。生理学报, 56 (1): 83-89。
所有作者: 发表杂志: 发表年份:2004
17. 髓背角II板层在长时程增强诱导及维持过程中的突触形态计量学研究。生理学报,56:397-402。
所有作者: 发表杂志: 发表年份:2004
18. The roles of CAMKII, PKA and PKC in the induction and maintenance of LTP of c-fiber evoked field potentials in rat spinal dorsal horn. J Neurophysiol,91 (3):1122-1133.
所有作者: 发表杂志: 发表年份:2004
19. Induction of long-term potentiation of C fibre-evoked spinal field potentials requires recruitment of group I, but not group II/III metabotropic glutamate receptors. Pain 106: 373-379.
所有作者: 发表杂志: 发表年份:2003
20. Protein synthesis inhibition blocks the late-phase LTP of C-fiber evoked field potentials in rat spinal dorsal horn. J. Neurophysiol. 89: 2354-2359.
所有作者: 发表杂志: 发表年份:2003
21. Time-dependent plasticity produced long-term potentiation of C-fiber evoked field potentials in rat spinal dorsal horn. Neurosci. Lett., 315: 81-84
所有作者: 发表杂志: 发表年份:2001
22. Sympathetic-sensory coupling after L5 spinal nerve lesion in the rat and its relation to changes in dorsal root ganglion blood flow. Pain, 87: 335-45
所有作者: 发表杂志: 发表年份:2000
23. Spontaneous activity of axotomized neurons after L5 spinal nerve injury in rats. Pain, 84:309-318.
所有作者: 发表杂志: 发表年份:2000
24. Axotomized and intact muscle afferents but no skin afferents develop ongoing discharges of dorsal root ganglion origin after peripheral nerve lesion. J. Neurosci, 20:2742-2748.
所有作者: 发表杂志: 发表年份:2000
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