2001-2004 中山大学 博士

2004-2011 中山大学 讲师、副教授 2007-2009 美国MD Anderson Cancer Center 博士后 2011-至今 中山大学 教授、博士生导师

近五年主持国家/省部级基金9项

包括：3项国家自然基金面上项目，1项教育部新世纪优秀人才

1：上调的δ-catenin通过棕榈酰化介导病理性疼痛的作用及机制，国家自然科学基金面上项目（31671090），67 万，2016.01-2019.12，项目负责人

2：miRNA在脊髓GABA能神经元sst2A受体抑制病理性疼痛中的作用及机制，广东省自然科学基金-重大基础研究培育 （2016.01-2019.12）， 100万元， 项目负责人

3： TLR4介导腹侧被盖区（VTA）小胶质细胞参与吗啡成瘾的作用及机制，国家自然科学基金面上项目 (81271474， 2013-2016)， 70万元， 项目负责人

4：脊髓小胶质细胞TLR4/CCL2信号通路在泰素诱导中枢敏感化和痛觉过敏中的作用，国家自然科学基金面上项目 (31171034， 2012-2015)， 70万元，项目负责人

5：Toll-Like Receptor 4信号通路在泰素诱导外周神经炎症中的作用， 教育部新世纪优秀人才支持计划（NCET-12-0568， 2013-2015)， 50万元， 项目负责人

近5年来共发表SCI论文28篇， 通讯作者/共同通讯作者：15篇，其中IF>5 : 9篇

1: Zhang XL, Ding HH, Xu T, Liu M, Ma C, Wu SL, Wei JY, Liu CC, Zhang SB, Xin WJ*: Palmitoylation of δ-catenin promotes kinesin-mediated mediated membrane trafficking of Nav1.6 in sensory neurons to promote neuropathic pain. Sci Signal 2018. (IF=6.494)（Cover Article, F1000）

2: Huang ZZ#, Wei JY#, Ou-Yang HD#, Li D, Xu T, Wu SL, Zhang XL, Liu CC, Ma C, Xin WJ*. mir-500-Mediated GAD67 DownregulationContributes to Neuropathic Pain. J Neurosci. 2016; 36:6321-6331. (IF: 6.344).

3: Huang ZZ, Li D, Ou-Yang HD, Liu CC, Liu XG, Ma C, Wei JY, Liu Y, Xin WJ * (2016) Cerebrospinal Fluid Oxaliplatin Contributes to the Acute Pain Induced by Systemic Administration of Oxaliplatin. Anesthesiology (IF: 5.879).

4: Xu, T#, Zhang, XL#, Ou-Yang, HD#, Li, ZY, Liu, CC, Huang, ZZ, Xu, J, Wei, JY, Nie, BL, Ma, C, Wu, SL, Xin, WJ*. Epigenetic upregulation of CXCL12 expression mediates antitubulin chemotherapeutics-induced neuropathic pain. Pain. 2016; Doi:10.1097/j.pain.0000000000000805.(IF=5.557 ).

5: Li D, Huang ZZ, Ling YZ, Wei JY, Cui Y, Zhang XZ*, Zhu HQ, Xin WJ *(2015) Up-regulation of CX3CL1 via Nuclear Factor-kappa B-dependent Histone Acetylation Is Involved in Paclitaxel-induced Peripheral Neuropathy. Anesthesiology 122:1142-1151 (IF: 6.168).

6: Huang ZZ, Li D, Liu CC, Li YY, Xin WJ * (2014) CX3CL1-mediated macrophage activation contributed to paclitaxel-induced DRG neuronal apoptosis and painful peripheral neuropathy. Brain, behavior, and immunity 40:155-165 (当年IF: 6.128).

7: Zhang J, Su YM, Li D, Cui Y, Huang ZZ，Xin WJ* (2014) TNF-alpha-mediated JNK activation in the dorsal root ganglion neurons contributes to Bortezomib-induced peripheral neuropathy. Brain, behavior, and immunity 38:185-191 (IF: 6.128).

8: Guo SJ#, Cui Y#, Huang ZZ#, Liu H, Zhang XQ*, Jiang JX, Xin WJ*. Orexin A-mediated AKT signaling in the dentate gyrus contributes to the acquisition, expression and reinstatement of morphine-induced conditioned place preference. Addict Biol. 2015; 21: 547-559. (IF=5.929)

9: Jiang JX#, Liu H#, Huang ZZ, Cui Y, Zhang XQ*, Zhang XL, Xin WJ*. The role of CA3-LS-VTA loop in the formation of conditioned place preference induced by context-associated reward memory for morphine. Addict Biol. 2016; Doi:10.1111/adb.12468.（IF=4.547）

10: Liu C, Luan S, OuYang H, Huang Z, Wu S, Ma C*, Wei J, Xin W* (2015) Upregulation of CCL2 via ATF3/c-Jun interaction mediated the Bortezomib-induced peripheral neuropathy. Brain, behavior, and immunity (IF: 5.889).

11: Zhang XQ, Cui Y, Chen Y, Na XD, Chen FY, Wei XH, Li YY, Liu XG, Xin WJ* (2012) Activation of p38 signaling in the microglia in the nucleus accumbens contributes to the acquisition and maintenance of morphine-induced conditioned place preference. Brain, behavior, and immunity 26:318-325 (IF: 5.612).