1994.9-1998.6，本科 吉林大学生命科学学院 生物技术专业

1998.9-2003.6，博士 吉林大学生命科学学院 生物化学与分子生物学

2004.8 -2007.5,美国Emory大学Human Genetics系 博士后 2007.6 -2009.8,美国Pittsburgh大学癌症中心 博士后 2009.9月-至今,中南大学生命科学学院医学遗传学研究中心 教授

回国后作为项目负责人，获得四项国家自然科学基金面上项目资助。作为技术骨干先后参与了两项973、一项自然科学基金重点项目和一项卫生部公益性行业科研专项的工作。

1. Chen J, Xue J, Ruan J, Zhao J, Tang B*,Duan R*. Drosophila CHIP protects against mitochondrial dysfunction by acting downstream of Pink1 in parallel with Parkin.FASEB J. 2017 Aug 4. pii: fj.201700011R. doi: 10.1096/fj.201700011R.

2. Bernstein A, Lin Y, Street RC, Lin L, Dai Q, Yu L, Bao H, Gearing M, Lah JJ, Nelson TP, He C, Levey A, Mulle JG,Duan R*, Jin P*. 5-Hydroxymethylation-associated epigenetic modifiers of Alzheimer's disease modulate Tau-induced neurotoxicity.HumMol Genet. 2016 Apr 9. pii: ddw109.

3.Duan R#,*，Shi Y*, Yu L, Zhang G, Li J, Lin Y, Guo J, Wang J, Shen L, Jiang H, Wang G, Tang B*. UBA5 mutations cause a new form of autosomal recessive cerebellar ataxia.Plos one. 2016 Feb 12;11(2):e0149039. doi: 10.1371/journal.pone.0149039.

4. Lin Y, He H, Luo Y, Zhu T,Duan R*. Inhibition of Transglutaminase Exacerbates Polyglutamine-induced Neurotoxicity by Increasing the Aggregation of Mutant Ataxin-3 in an SCA3 Drosophila Model.Neurotox Res. 2015 27:259-267.

5. Luo S, Huang W, Chen C,Duan R*, Wu L*. A novel deletion to normal size in the sperm of a fragile X full mutation male.Clin Genet. 2014 Sep;86(3):295-297. Epub 2013 Oct 23.

6. Zhang M, Chen J, Si D, Zheng Y, Jiao H, Feng Z, Hu Z*,Duan R*. Whole exome sequencing identifies a novel EMD mutation in a Chinese family with dilated cardiomyopathy.BMC Med Genet. 2014 Jul 5;15(1):77.

7. Huang W, Luo S, Ou J, Zhu F, Xia Y, Xue J, Pan Q, Wu L*,Duan R*. Correlation between FMR1 expression and clinical phenotype in discordant dichorionic–diamniotic monozygotic twin sisters with the fragile x mutation.J Med Genet. 2014 Mar;51(3):159-64. Epub 2013 Nov 27.

8. Lin Y, Tang C, He H,Duan R*. Activation of mTOR Ameliorates Fragile X Premutation rCGG repeat-mediated Neurodegeneration.PLoS One. 2013 Apr 23; 8(4):e62572.

9. Wang T, Pan Q, Lin L, Szulwach KE, Song CX, He C, Wu H, Warren ST, Jin P*,Duan R*, Li X*. Genome-wide DNA hydroxymethylation changes are associated with neurodevelopmental genes in the developing human cerebellum.Hum Mol Genet. 2012 Dec 15;21(26):5500-10.

10. Jin P*,Duan R*, Qurashi A, Qin Y, Tian D, Rosser TC, Liu H, Feng Y, Warren ST. Pur alpha binds to rCGG repeats and modulates repeat-mediated neurodegeneration in a Drosophila model of fragile X tremor/ataxia syndrome.Neuron. 2007 Aug 16;55(4):556-64.