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衣馨瑶

领域:新材料产业 学校:中南大学职称:副教授

生物传感与表面分析,老年神经退行性疾病机理的探究以及疾病标志物检测手段的开发...

具体了解该专家信息,请致电:027-87555799 邮箱 haizhi@uipplus.com

教育背景

2011.7-2013.7
加州州立大学洛杉矶分校 | 分析化学
联合培养
2005.9-2009.6
中南大学 | 应用化学
学士学位 | 大学本科毕业
2009.9-2014.6
中南大学 | 分析化学
博士学位 | 博士研究生毕业
硕博连读

工作经历

2015.1-至今 化学化工学院 | 中南大学

项目课题经历

主持国家自然科学基金青年基金一项,湖南省自然科学基金青年基金一项。

论文、成果、著作等

[1] Multiplexed electrochemical detection of miRNAs from sera of glioma patients at different stages via the novel conjugates of conducting magnetic microbeads and diblock oligonucleotide- modified gold nanoparticles. Anal. Chem, 2017, 89: 10834−10840
[2] Sensitive and simultaneous surface plasmon resonance detection of free and p53-bound MDM2 proteins from human sarcomas. Analyst, 2018, 143: 2029-2034
[3] Voltammetric determination of the Alzheimer's disease-related ApoE 4 gene from unamplified genomic DNA extracts by ferrocene-capped gold nanoparticles. Microchim. Acta, 2018, 185: 549
[4] Sensitive surface plasmon resonance detection of methyltransferase activity and screening of its inhibitors amplified by p53 protein bound to methylation-specific ds-DNA consensus sites. Biosens. Bioelectron., 126: 269-274
[5] Dual-channel surface plasmon resonance for quantification of apoE gene and genotype discrimination in unamplified genomic DNA extracts. ACS sens., 2018, 3: 2402−2407
[6] Triple stimuli-responsive magnetic hollow porous carbon-based nanodrug delivery system for magnetic resonance imaging-guided synergistic photothermal/chemotherapy of cancer. [J]. ACS Appl. Mater. Interfaces., 2018, 10: 21939-21949.
[7] Yi, Xinyao, Hao,Yuanqiang,Xia, Ning,Li, Ding,Wang, Jianxiu. Sensitive and continuous screening of inhibitors of beta-siteamyloid precursor protein cleaving enzyme 1 (BACE1) at single SPR chips [J]. Analytical Chemistry, 2012, 85(7): 3660-3666
[8] Yi, Xinyao,Han, Hongxing,Zhang, Yu,Wang, Jianxiu ,Zhang,Yi. Amplified voltammetric characterization of cleavage of the biotinylated peptideby BACE1 and screening of BACE1 inhibitor [J]. Biosensors and Bioelectronics, 50: 224-228
[9] Yi,Xinyao ,Feng,Chengting,Hu,Shengqiang,Li,Hengfeng,Wang,Jianxiu. Surface plasmon resonance biosensors for simultaneous monitoring ofamyloid-beta oligomers and fibrils and screening of select modulators Analyst, 2016, 141(1):
[10] Yi, Xinyao ,Zhang, Yi,Gong, Ming,Yu, Xiang,Darabedian,. Ca(II) interacts with Glu-22 of a-beta(1-42) and phospholipid bilayers to accelerate the a-beta(1-42)aggregation below the critical micelle concentration Biochemistry, 2016, 54(41): 6326-6332
[11] Wang, Jianxiu,Yi,Xinyao,Tang, Hailin,Han,Hongxing,Wu,. Direct quantification of microRNA at low picomolar level in sera of glioma patients using a competitive hybridization followed by [J]. Analytical Chemistry, 84(15): 6400-6406
[12] Yang, Minghui,Yi, Xinyao,Wang, Jianxiu(*),Zhou, Feimeng. Electroanalytical and surface plasmon resonance sensors for detection of breast cancer Analyst, 2014, 139(8): 1814-1825

专利、著作版权等

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