2006/09-2012/06，中南大学，湘雅公共卫生学院，卫生毒理学系，博士；

2001/09-2006/06，中南大学，湘雅医学院，预防医学专业，本科

2016/10-至今，中南大学湘雅公共卫生学院，卫生毒理学系，副教授；2012/12-2016/09，中南大学湘雅公共卫生学院，卫生毒理学系，讲师； 2013/04-2016/04，中南大学生命科学学院，博士后； 2009/08-2011/08，美国犹他大学（University of Utah）医学院，肿瘤研究所，联合培养博士生（国家建设高水平大学公派研究生项目）。

1. 国家自然科学基金（面上项目），簇集蛋白（Clusterin）介导的衰老相关分泌表型（SASP）在六价铬[Cr(VI)] 诱导的肝细胞恶性转化中的作用研究，81773478，201801-202112；

2. 国家自然科学基金（青年项目），簇集蛋白（Clusterin）在六价铬[Cr(Ⅵ)]诱导的肝细胞早熟性衰老中的作用研究，81302456，201401-201612；

3. 湖南省自然科学基金（青年项目），IP3R-SOCC在Cr(Ⅵ)诱导的肝细胞自噬中的作用研究，2015JJ3135，201501-201712；

4. 中国博士后科学基金（第54批），簇集蛋白在六价铬诱导的肝细胞早熟性衰老中的作用研究，2013M542144，201401-201512；

5. 中国博士后科学基金特别资助（第七批），Cr(Ⅵ)对肝细胞IP3R-SOCC的影响及其与自噬关系的研究，2014T70792，201501-201612；

6. 高等学校博士学科点专项科研基金（新教师类），簇集蛋白（Clusterin）在六价铬[Cr(VI)]诱导的肝细胞早熟性衰老中的分子作用机制研究，20130162120076, 201401-201612；

7. 中南大学科学研究启动基金，簇集蛋白（Clusterin）在六价铬[Cr(VI)]诱导的肝细胞早衰中的作用机制研究

1. Yuanyuan Xiao, Ming Zeng, Lirong Yin, Na Li and Fang Xiao*. Clusterin increases mitochondrial respiratory chain complex I activity and protects against hexavalent chromium-induced cytotoxicity in L-02 hepatocytes. Toxicology Research. 2019, 8(1):15-24.

2. Qi Liang, Yujing Zhang, Manfeng Huang, Yuanyuan Xiao, and Fang Xiao*. Role of mitochondrial damage in Cr(VI)-induced endoplasmic reticulum stress in L-02 hepatocytes. Molecular Medicine Reports. 2019,19: 1256-1265.

3. Qi Liang, Yujing Zhang, Ming Zeng, Lan Guan, Yuanyuan Xiao, and Fang Xiao*. The role of IP3R-SOCCs in Cr(VI)-induced cytosolic Ca2+ overload and apoptosis in L-02 hepatocytes. Toxicology Research. 2018, 7(3), 521-528.

4. Xiali Zhong#, Ming Zeng#, Huanfeng Bian, Caigao Zhong, and Fang Xiao*. An evaluation of the protective role of vitamin C in reactive oxygen species-induced hepatotoxicity due to hexavalent chromium in vitro and in vivo. Journal of Occupational Medicine and Toxicology. 2017,12:15.

5. Xing Yi, Yujing Zhang, Caigao Zhong, Xiali Zhong and Fang Xiao*. The role of STIM1 in the Cr(VI)-induced [Ca2+]i increase and cell injury in L-02 hepatocytes. Metallomics. 2016, 8(12):1273-1282.

6. Yujing Zhang, Yiyuan Zhang, Caigao Zhong and Fang Xiao*. Cr(VI) induces premature senescence through ROS-mediated p53 pathway in L-02 hepatocytes. Sci. Rep. 2016, 6, 34578; doi: 10.1038/srep34578.

7. Ming Zenga, Rui-Xue Huang, Wen-Yi Li , Xiao-Wen Liu, Fu-Ling He, Yi-Yuan Zhang and Fang Xiao*. In(OTf)3/Acid Co-catalyzed Hydration of 1-Haloalkynes to α-Halomethyl Ketones. Tetrahedron, 2016, 72(27-28):3818-3822.

8. Feng Shi, Fang Xiao, Ping Ding, Hong Qin, and Ruixue Huang*.Long Noncoding RNA Highly Up-regulated in Liver Cancer Predicts Unfavorable Outcome and Regulates Metastasis by MMPs in Triple-negative Breast Cancer. Arch Med Res, 2016, 47(6):446-453.

9. Fang Xiao, Yanhong Li, Lei Luo, YingXie, Ming Zeng, Caigao Zhong*. Role of mitochondrial electron transport chain dysfunctionin Cr(Ⅵ)-induced cytotoxicity in L-02 hepatocytes. Cell Physiol Biochem, 2014, 33(4):1013-1025.

10. Fang Xiao, Dongfang Chen, Lei Luo, XialiZhong, Ying Xie, Ming Zeng, Lan Guan, Xinmin Liu, and CaigaoZhong*. Time order effects of vitamin C on hexavalent chromium induced mitochondrial damage and DNA protein crosslinks in cultured rat peripheral blood lymphocytes. Mol Med Rep, 2013, 8(1): 53-60.

11. Fang Xiao, Xiaotao Feng, Ming Zeng, LanGuan, Qingqing Hu, and Caigao Zhong*.Hexavalent chromium induces energy metabolism disturbance and p53-dependent cell cycle arrest via reactive oxygen species in L-02 hepatocytes. Mol Cell Biochem, 2012, 371 (1-2):65-76.

12. Fang Xiao, Yanhong Li, Lu Dai, YuanyuanDeng, Yue Zou, Peng Li, Yuan Yang, and Caigao Zhong*.Hexavalent chromium targets mitochondrial respiratory chain complex I to induce reactive oxygen species-dependent caspase-3 activation in L-02 hepatocytes. Int J Mol Med, 2012, 30 (3):629-635.

13. Lan Guan, Xinmin Liu, Fang Xiao, Ming Zeng, and Ying Chen. Characterization of Elastic Niosomes Prepared with Various Nonionic Surfactants for Lidocaine Hydrochloride Transdermal Delivery.《Nanoscience & Nanotechnology Letters》, 2016, 8(12):1033-1039.

14. Xing Yi, Fang Xiao, Xiali Zhong, Yujie Duan, Kaihua Liu, Caigao Zhong*. A Ca2+ chelator ameliorates chromium (VI)-induced hepatocyte L-02 injury via down-regulation of voltage-Dependent anion channel 1 (VDAC1) expression. Environ Toxicol Pharmacol. 2016,18(49):27-33.

15. Ying Xie, Fang Xiao, LeiLuo, Caigao Zhong*. Activation of autophagy protects against ROS-mediated mitochondria-dependent apoptosis in L-02 hepatocytes induced by Cr(Ⅵ). Cell Physiol Biochem, 2014, 33(3):705-716.

16. Ming Zeng, Fang Xiao, Xiali Zhong, Feng Jin, Lan Guan, An Wang, Xinmin Liu, and Caigao Zhong*.Reactive oxygen species plays a central role in hexavalent chromium-induced apoptosis in Hep3B cells without the functional role of p53 and caspase-3. Cell Physiol Biochem, 2013, 32(2):279-290.

17. Lei Luo, Ying Xie, Fang Xiao, Xiali Zhong, and Caigao Zhong*. Desipramine ameliorates Cr(VI)-induced hepatocellular apoptosis via the inhibition of ceramide channel formation and mitochondrial PTP opening. Cell Physiol Biochem, 2014, 34.

18. Lei Shi, Siqing Wang,Maurizio Zangari, Hongwei Xu,Thai M Cao, Chunjiao Xu, Yong Wu, Fang Xiao, Yinghong Liu, Guido Tricot, and Fenghuang Zhan*.Over-expression of CKS1B activates both MEK/ERK and JAK/STAT3 signalingpathways and promotes myeloma cell drug-resistance. Oncotarget. 2010,1(1):22-33.