1980-1985年 遵义医学院口腔医学系学习，获学士学位1989-1993年 北京大学口腔医学院学习，获博士学位

1985-1989年 遵义医学院口腔医学系担任助教1993-1998年 遵义医学院口腔医学系担任助教、讲师、副教授

1.β防御素在牙龈卟啉单胞菌脂多糖促动脉粥样硬化形成中的保护作用（81371152）国家自然科学基金 主持 2014,01-2017,12

2.重度牙周炎的规范化诊疗研究（BL2013002） 江苏省临床医学科技专项重点病种的规范化诊疗研究 主持 2013,07-2016,06

3.β防御素抑制牙龈卟啉单胞菌脂多糖对巨噬细胞的促炎症反应（BK20131079）江苏省自然科学基金 主持 2013,07-2016,06

4.hVEGF／hBD3双基因修饰的组织工程化复合物修复牙周组织缺损的实验研究（201303051）南京市国际合作交流基金 主持 2013,07-2015，06

5.牙龈卟啉单胞菌牙周感染与高脂血症的相互影响及其在ApoE基因敲除小鼠动脉粥样硬化形成中的作用（81170973） 国家自然科学基金 主持2012,01-2015,12

1. Chen S, Lin G, You X, Lei L, Li Y, Lin M, Luo K, Yan F. Hyperlipidemia causes changes in inflammatory responses by periodontal pathogen challenge: Implications in acute and chronic infections. Arch Oral Biol. 2014 Jun 21;59(10):1075-1084. (5 Year IF:1.624)

2. Chen B, Wu W, Sun W, Zhang Q, Yan F, Xiao Y. RANKL expression in periodontal disease: where does RANKL come from? Biomed Res Int. 2014;2014: 731039. Epub 2014 Feb 27. (5 Year IF: 2.88)

1. 3. Zhang Q, Chen B, Yan F, Guo J, Zhu X, Ma S, Yang W. Interleukin-10 Inhibits Bone Resorption: A Potential Therapeutic Strategy in Periodontitis and Other Bone Loss Diseases. Biomed Res Int. 2014;2014: 284836. Epub 2014 Feb 16. (5 Year IF: 2.88)

2.4. Luo K, Ma S, Guo J, Huang Y, Yan F, Xiao Y. Association between Postmenopausal Osteoporosis and Experimental Periodontitis. Biomed Res Int. 2014;2014:316134. doi: 10.1155/2014/316134. Epub 2014 Feb 10(5 Year IF: 2.88)

3.5.Zhu X, Yuan F, Li H, Zheng Y, Xiao Y, Yan F. Evaluation of canine bone marrow-derived mesenchymal stem cells after long-term cryopreservation. Zoolog Sci. 2013 Dec;30(12):1032-7. (5 Year IF:1.076)

4.6. Lang Lei， Houxuan Li， Fuhua Yan，Yin Xiao. Hyperlipidemia impaired innate immune response to periodontal pathogen Porphyromonas gingivalis in Apolipoprotein E knockout mice. PLoS One. 2013 ;8(8):e71849 . (5 Year IF:3.73)

5.7. Suai Chen, Genbin Lin, Lang Lei, Xiaoqing You, Chunfang Wu, Wenjing Xu, Meixiang Huang, Kai Luo, Zhijun Wang, Yanfen Li, Xin Zhao, Fuhua Yan. Hyperlipidemia Modifies Innate Immune Responses to Lipopolysaccharide via the TLR-NF-κB Signaling Pathway. Inflammation. 2013 ;36(4):968-76. (5 Year IF:2.457)

6.8. Wei Liu, Xiaohong Wu, Hongbing Zhan, Fuhua Yan. Synthesis of bioactive poly(ethylene glycol)/SiO2-CaO-P2O5 hybrids for bone regeneration. Materials Science and Engineering C. 2012;32:707-711. (5 Year IF:2.404)

7.9. Lang Lei, Houxuan Li, Fuhua Yan, Yanfen Li , Yin Xiao. Porphyromonas gingivalis lipopolysaccharide alters atherosclerotic-related gene expression in oxidized low-density-lipoprotein-induced macrophages and foam cells. Journal of Periodontal Research. 2011,46(4):427-437. (5 Year IF:1.99)

10. Hongbing Lv, Sheng Fu, Gancha Wu, Fuhua Yan. PHEX neutralizing agent inhibits dentin formation in mouse tooth germ. Tissue and Cell. 2011;43(2):125-130. (5 Year IF:1.038)

11.Shouzhi Ma , Jianbin Guo, Xiaoqing You, Wen Xia, FuhuaYan. Expressions of interleukin-1β and interleukin-6 within aortas and uteri of rats with various severities of ligature-induced periodontitis. Inflammation. 2011 ;34(4):260-268. (5 Year IF: 2.457)

12. Jun Jiang, Xiaohong Wu, Minkui Lin, Nghiem Doan, Yin Xiao, Fuhua Yan. Application of autologous periosteal cells for the regeneration of class III furcation defects in Beagle dogs. Cytotechnology. 2010, 62(3):235–243. (5 Year IF:1.315)

13. Kunqi Tang, Minkui Lin, Yun Wu, Fuhua Yan. Alterations of serum lipid and inflammatory cytokine profiles in the patients of coronary heart disease with chronic periodontitis: A Pilot Study. The Journal of International Medical Research. 2010, 39(1):238-248. (5 Year IF:0.958)

14. Zhibin Du, Jiang Chen, Fuhua Yan, Yin Xiao. The effects of simvastatin on bone healing around titanium implants in osteoporotic rats. Clinical Oral Implants Research. 2009, 20(2):145-150. (5 Year IF:3.433)

15.Houxuan Li, Fuhua Yan, Lang Lei, Yanfen Li, Yin Xiao. Application of autologous cryopreserved bone marrow mesenchymal stem cells for periodontal regeneration in dogs. Cells Tissues Organs. 2009,190:94-101. (5 Year IF:1.961)

16.Xiaohong Wu，Minkui Lin，Yanfen Li，Xin Zhao，Fuhua Yan. Effects of DMEM and RPMI 1640 on the biologicsal behavior of dog periosteum-derived cells. Cytotechnology. 2009,59:103-111. (5 Year IF:1.315)