南京大学化学学士、生物学硕士、遗传学博士。历任南京大学医学院讲师、副教授，硕士生导师。

2012.07-2015.06，江苏省自然科学基金面上项目，“MLH1 pre-mRNA选择性剪接的表观遗传调控及其对胃癌预后与治疗的指导意义研究”；

2013.08-2014.04，横向科研项目，“粪便DNA甲基化在结直肠肿瘤早期筛查中的价值研究”；

2010.01-2012.12，国家自然科学基金面上项目，“抑癌基因胚系表观突变与胃癌遗传易感性的研究”；

2008.3-2010.12，江苏省自然科学基金面上项目，“胃肠肿瘤分子诊断中基因突变功能评估体系的研究”；

.Li XW, Gao YF, Pan YY, Pan Y, Wang LF, Xiao N, He Q, Fan YM*, Wang YP*. Mutation screen and RNA analysis disclose the changed splicing of the E-cadherin transcription in gastric cancer. Familial Cancer 2013; 12:547-554. (共同通讯作者).


2.Chen QH, Deng W, Li XW, Liu XF, Wang JM, Wang LF, Xiao N, He Q, Wang YP, Fan YM*. Novel CDH1 germline mutations identified in Chinese gastric cancer patients. World J Gastroenterol 19:909-916, 2013 (通讯作者).


3.Zhi WX, Xue BS, Wang LF , Xiao N, He Q, Wang YP, Fan YM*. The MLH1 2101C>A (Q701K) variant increases the risk of gastric cancer in Chinese males. BMC Gastroenterology 11:133, 2011 (通讯作者).


4.Fan YM, Chen JY, Wang W, Wu PY, Zhi WX, Xue BS, Zhang WF, Wang YP. Influence of Eight Unclassified Missense Variants of the MLH1 Gene on Lynch Syndrome Susceptibility. Biochemical Genetics 50:84-93, 2012. Epub 2011 Sep 28.


5.Wu PY, Zhang Z, Wang JM, Guo WW, Xiao N, He Q, Wang YP, Fan YM*. Germline promoter hypermethylation of tumor suppressor genes in gastric cancer. World J Gastroenterol 18:70-78, 2012 (通讯作者).


6.Fan YM, Wang W, Zhu M, Zhou JJ, Peng JY, Xu LZ, Hua ZC, Gao X, Wang YP. Analysis of hMLH1 missense mutations in East Asian patients with suspected hereditary nonpolyposis colorectal cancer. Clin Cancer Res 13: 7515-7521, 2007.


7.Fan YM, Liu XR, Zhang H, Dai J, Zhang XM, Zhu M, Gao Xiang, Wang YP. The hMSH2 variations in exon 7 and their association with susceptibility to gastrointestinal cancer. Cancer Genet Cytogenet 170:121-128, 2006.

获发明专利授权3项