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胡娅莉

领域:生物产业 学校:南京大学职称:教授

围产医学...

具体了解该专家信息,请致电:027-87555799 邮箱 haizhi@uipplus.com

教育背景

工作经历

项目课题经历


1.他汀类药物通过miR155改善子痫前期小鼠血管内皮功能障碍的机制研究

国家自然科学基金 面上项目 2013-2016(81370724)

2.miR-155调控TLR4信号,参与子痫前期发病的机制研究

国家自然科学基金 面上项目 2011-2013(81070508)

3.微小RNA-miR-155调控子痫前期胎盘血管形成的机制研究

国家自然科学基金 面上项目 2009-2011(30872775)

4.国家临床重点专科建设项目 2010-2014

5.国家重大基础科学研究(973)卵巢早衰的临床候选基因筛选

6.国务院战略先导计划 子宫壁修复的研究

7.卫生部行业专项(胎儿重大疾病诊治)

8.产前出生缺陷诊疗技术的集成创新研究(省科技厅临床重点专项)

9.江苏省十二五重点学科(母胎医学)

10.南京市临床医学中心(妇产与遗传中心

论文、成果、著作等

1.Ding LJ… Hu YL(通信作者) Transplantation of bone marrow mesenchymal stem cells on collagen scaffolds regenerates functional rat uterus after full-thickness injury Biomaterials 2014, 35:4888-4900

2.Xue PP… Hu YL(通信作者)miR-155* mediates suppressive effect of PTEN 3'-untranslated region on AP-1/NF-κB pathway in HTR-8/SVneo cells. Placenta. 2013 Aug;34(8):650-6

3.Haiyan Zhu, Hu YL(通信作者) A Boy With Partial Trisomy of Chromosome 3q24–q28 from Paternal Balanced Insertion and Multiple Congenital Anomalies Am J Med Genet A. 2013, 161A(2):327-30

4.Chen X, Chen J, Wen J, Xu C, Zhang S, Zhou YH, Hu YL(通信作者) Breastfeeding Is Not a Risk Factor for Mother-to-Child Transmission of Hepatitis B Virus. PLoS One 2013;8(1):e55303.

5.Hu YL Chen J, Wen J, Xu C, Zhang S, Xu B, Zhou YH. Effect of elective cesarean section on the risk of mother-to-child transmission of hepatitis B virus. BMC Pregnancy and Childbirth 2013;13:119.

6.Hu YL Dai X, Zhou YH, Yang H. A knowledge survey of obstetrics and gynecology staff on the prevention of mother-to-child transmission of hepatitis B virus. J Infect Dev Ctries 2013;7(5):391-7.

7.He QY, … Hu YL(通信作者) FSH modulates the expression of inhibin-alpha and the secretion of inhibins via orphan nuclear receptor NUR77 in ovarian granulosa cells.FEBS Lett. 2013 Aug 2;587(15):2474-82.

8.Dai AY,… Hu YL (通信作者) MicroRNA-133b stimulates ovarian estradiol synthesis by targeting Foxl2. FEBS Lett. 2013 Aug 2;587(15):2474-82

9.Zhang Q, … Hu YL(通信作者) MicroRNA-181a suppresses mouse granulosa cell proliferation by targeting activin receptor IIA. PLoS One. 2013;8(3):e59667

10.Lin NC,… Hu YL (通信作者) The effect of collagen-bingding vascular endothelial growth factor on the remodeling of acarred rat uterus following full-thickness injury. Biomaterials 2012, 33:1801-1807

11.Zhang X,…Hu YL(通信作者) NUR77 inhibits the expression of TIMP2 and increases the migration and invasion of HTR-8/SVneo cells induced by CYR61 Placenta 2012 , 33 561-567

12.Zhang X, … Hu YL (通信作者)CYR61 Modulates the Vascular Endothelial Growth Factor C Expression of Decidual NK Cells Via PI3K⁄AKT Pathway Am J Reprod Immunol 2012, 67:216-23

13.Dai A,… Hu YL (通信作者) Orphan nuclear receptor nur77 regulates androgen receptor gene expression in mouse ovary PLoS One. 2012;7(6):e39950

14.Zhou J,… Hu YL(通信作者) Combination of lipids and uric acid in mid-second trimester can be used to predict adverse pregnancy outcomes. J Matern Fetal Neonatal Med. 2012,25:2633-8

15.Zhou J,… Hu Y L(通信作者)An Increase of Treg Cells in the Peripheral Blood is Associated with a Better In Vitro Fertilization Treatment Outcome Am J Reprod Immunol. 2012, 68:100- 6.

16.Li Xin’an,… Hu YL. (通信作者)Regeneration of uterine horns in rats by collagen scaffolds loaded with collagen binding human basic fibroblast growth factor. Biomaterials 2011, 32:8172-8181

17.Wang Zhiqun, … Hu YL(通信作者) Transplacentally acquired maternal antibody against hepatitis B surface antigen in infants and its influence on the response to hepatitis B vaccine. PLoS One 2011;6:e25130.

18.Dai Yimin,… Hu YL (通信作者) MicroRNA-155is involved in remodeling of human- trophoblast derived HTR-8/SVneo cells induced by lipopolysaccharides Hum Reprod 2011,26:1882-91

19.Zhang Yanqing…Hu YL(通信作者) MicroRNA-155 contributes to preeclampsia by down-regulating CYR 61 Am J Obstet Gynecol 2010, 202(5):466.e1-7

20.Shen Y, Hu YL(通信作者) Favorable maternal and fetal effects of Danshensu in an experimental mice model of preeclampsia. Hypertension in pregnancy 2011,30:465-80

21.Zheng MM, Hu YL(通信作者) Comparison of second-trimester maternal serum free-βHCG and α-AFP between normal singleton and twin pregnancies: a population-based study Chin Med J 2010, 123:555-558

22.Zhang S,… Hu YL(通信作者) Monitoring human cytomegalovirus infection with nested PCR: comparison of positive rates in plasma and leukocytes and with quantitative PCR. Virol J. 2010, 7:73-80.

23.Zhang S,…Hu YL(通信作者)Seroprevalence of hepatitis B surface antigen among pregnant women in Jiangsu, China, 17years after introduction of hepatitis B vaccine. Int J Gynaecol Obstet. 2010 ,109(3):194-7.

24.Zhou JJ, Hu YL(通信作者)…. Imbalance of T-cell transcription factors contributes to the Th1 type immunity predominant in pre-eclampsia. Am J Reprod Immunol. 2010, 63:38-45.

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