1982年-1989年，江苏省医药工业研究所 1989年-2001年，中国药科大学药学院 2001年-至今，南京大学生命科学学院

国家重点研发计划-纳米科技（2017YFA0205400）：肿瘤乏氧微环境相关的纳米药物设计及其规模化制备研究

国家自然科学基金面上基金（81872811）：F19携氧纳米辅助诊疗系统的构建及在肿瘤射频消融手术中的应用

国家自然科学基金面上基金（81473146）：可示踪可激发体内双级递氧体系构建与评价

国家自然科学基金面上基金（81273464）：MSC-前药酶/前药”脑肿瘤精确给药系统

国家自然科学基金面上基金（30973651）：小分子对苦味物质真溶液的苦味自淬灭研究

国家自然科学基金（30070897）：蛋白质在聚合物中的热稳定性与空间构象及生理活性的关系

重大新药创制国家科技重大专项：多西他赛白蛋白纳米粒靶向抗肿瘤的临床前研究

国家科技重大专项：蛋白质结肠定位给药系统

国家科技重大专项：盐酸非洛普缓释片

Lingtong Meng, Yali Cheng, Xiaoning Tong, Shaoju Gan, Yawen Ding, Yu Zhang, Chao Wang, Lei Xu, Yishen Zhu, Jinhui Wu, Yiqiao Hu*, and Ahu Yuan. Tumor Oxygenation and Hypoxia Inducible Factor-1 Functional Inhibition via a Reactive Oxygen Species Responsive Nanoplatform for Enhancing Radiation Therapy and Abscopal Effects [J]. ACS nano, 2018, 12(8): 8308-8322.

Zaigang Zhou, Baoli Zhang, Shushan Wang, Wenjing Zai, Ahu Yuan, Yiqiao Hu*, Jinhui Wu. Perfluorocarbon Nanoparticles Mediated Platelet Blocking Disrupt Vascular Barriers to Improve the Efficacy of Oxygen‐Sensitive Antitumor Drugs [J]. Small, 2018: 1801694.

Zaigang Zhou, Baoli Zhang, Haoran Wang, Ahu Yuan, Yiqiao Hu*, and Jinhui Wu. Two-stage oxygen delivery for enhanced radiotherapy by perfluorocarbon nanoparticles [J]. Theranostics. 2018; 8(18): 4898-4911.

Lingtong Meng, Yali Cheng, Shaoju Gan, Zhicheng Zhang, Xiaoning Tong, Lei Xu, Xing Jiang, Yishen Zhu, Jinhui Wu, Ahu Yuan, and Yiqiao Hu*. Facile Deposition of Manganese Dioxide to Albumin-Bound Paclitaxel Nanoparticles for Modulation of Hypoxic Tumor Microenvironment To Improve Chemoradiation Therapy [J]. Molecular pharmaceutics, 2018, 15(2): 447-457.

Hao Ren, Jiaqi Liu, Fenhong Su, Sizhan Ge, Ahu Yuan, Weimin Dai, Jinhui Wu, and Yiqiao Hu*. Relighting Photosensitizers by Synergistic Integration of Albumin and Perfluorocarbon for Enhanced Photodynamic Therapy [J]. ACS applied materials & interfaces, 2017, 9(4):3463-3473.

Hao Ren, Jiaqi Liu, Yuqin Li, Haoran Wang, Sizhan Ge, Ahu Yuan, Yiqiao Hu*, Jinhui Wu. Oxygen self-enriched nanoparticles functionalized with erythrocyte membranes for long circulation and enhanced phototherapy [J]. Acta Biomaterialia,59(1);269-282

Xiaolei Tang, Yuhao Cheng, Shiting Huang, Feng Zhi, AhuYuan, Yiqiao Hu*, Jinhui Wu. Overcome the limitation of hypoxia against photodynamic therapy to treat cancer cells by using perfluorocarbon nanodroplet for photosensitizer delivery [J]. Biochemical and Biophysical Research Communications, 2017, 487(3): 483-487

Xing Jiang, Baoli Zhang, Zaigang Zhou, Lingtong Meng, Zhiling Sun, Yun Xu, Qiuping Xu, Ahu Yuan, Lixia Yu, Hanqing Qian, Jinhui Wu, Yiqiao Hu*& Baorui Liu. Enhancement of radiotherapy efficacy by pleiotropic liposomes encapsulated paclitaxel and perfluorotributylamine [J]. Drug delivery, 2017, 24(1): 1419-1428.

Yifan Zhang, Yuncai Guan, Sizhan Ge, Ahu Yuan, Jinhui Wu and Yiqiao Hu*. Light-responsive CO2bubble-generating polymeric micelles for tumor cell Ablation [J].MedChemComm, 2017, 8(2): 405-407.

Yifan Zhang, Lingyi He, Jie Wu, Kaikai Wang, Juan Wang, Weimin Dai, Ahu Yuan, Jinhui Wu, Yiqiao Hu*. Switchable PDT for reducing skin photosensitization by a NIR dye inducing self-assembled and photo-disassembled nanoparticles [J]. Biomaterials, 2016, 107: 23-32.

Yifan Zhang, Youwei Zhu, Na Zhao, Jinhui Wu, Yiqiao Hu*. Application of isothermal titration calorimeter for screening bitterness suppressing molecules of quinine [J]. Food chemistry, 2016, 190: 1007-1012.

Kaikai Wang, Yifan Zhang, Juan Wang, Ahu Yuan, Minjie Sun, Jinhui Wu & Yiqiao Hu*. Self-assembled IR780-loaded transferrin nanoparticles as an imaging, targeting and PDT/PTT agent for cancer therapy [J]. Scientific reports, 2016, 6: 27421

Linfeng Xu, Xuefeng Qiu, Yanting Zhang, Kai Cao, Xiaozhi Zhao, Jinhui Wu, Yiqiao Hu*and Hongqian Guo. Liposome encapsulated perfluorohexane enhances radiotherapy in mice without additional oxygen supply [J]. Journal of translational medicine, 2016, 14(1): 268

Ahu Yuan, Wei Huan, Xiang Liu, Zhicheng Zhang, Yifan Zhang, Jinhui Wu, and Yiqiao Hu*. One-step self-assembling method to prepare dual-functional transferrin nanoparticles for antitumor drug delivery [J]. J Pharm Sci, 2016,105(3):1269-1276

Ahu Yuan, Wei Huan, Xiang Liu, Zhicheng Zhang, Yifan Zhang, Jinhui Wu, and Yiqiao Hu*. NIR Light-Activated Drug Release for Synergetic Chemo–Photothermal Therapy [J].Molecular pharmaceutics, 2016, 14(1): 242-251.

Tingsheng Lin, Xiaozhi Zhao, Yifan Zhang, Huibo Lian, Junlong Zhuang, Qing Zhang, Wei Chen, Wei Wang, Guangxiang Liu, Suhan Guo, Jinhui Wu, Yiqiao Hu*, and Hongqian Guo. Floating Hydrogel with Self-Generating Micro-Bubbles for Intravesical Instillation [J]. Materials, 2016, 9(12): 1005.

Xuefeng Qiu, Linfeng Xu, Yanting Zhang, Ahu Yuan, Kaikai Wang, Xiaozhi Zhao, Jinhui Wu, Hongqian Guo, and Yiqiao Hu*. Photothermal Ablation of in Situ Renal Tumor by PEG-IR780-C13 Micelles and Near-Infrared Irradiation [J]. Molecular pharmaceutics, 2016, 13(3): 829-838.

Ahu Yuan, Xiaolei Tang, Xuefeng Qiu, Ke Jiang, Jinhui Wu and Yiqiao Hu*. Activatable photodynamic destruction of cancer cells by NIR dye/photosensitizer loaded liposomes [J]. Chemical Communications, 2015, 51(16): 3340-3342.

Ahu Yuan, Xuefeng Qiu, Xiaolei Tang, Wei Liu, Jinhui Wu, Yiqiao Hu*. Self-assembled PEG-IR-780-C13 micelle as a targeting, safe and highly-effective photothermal agent for in vivo imaging and cancer therapy [J]. Biomaterials, 2015, 51: 184-193.

Zhengjie Meng, Xiaoyan Yang, Die Hu, Kaikai Wang, Feng Zhi, Xi Chen, Guangming Gong, Jinhui Wu, Yiqiao Hu*. Replacing heme with paclitaxel to prepare drug-loaded globin nanoassembles for CD163 targeting [J]. Journal of pharmaceutical sciences, 2015, 104(3): 1045-1055.

Chenxiao Jiang, Hao Cheng, Ahu Yuan, Xiaolei Tang, Jinhui Wu, Yiqiao Hu*. Hydrophobic IR780 encapsulated in biodegradable human serum albumin nanoparticles for photothermal and photodynamic therapy [J]. Acta biomaterialia, 2015, 14: 61-69.

Zhengjie Meng, Lingtong Meng, Kaikai Wang, Jing Li, Xiaoli Cao, Jinhui Wu, Yiqiao Hu*. Enhanced hepatic targeting, biodistribution and antifibrotic efficacy of tanshinone IIA loaded globin nanoparticles [J]. European Journal of Pharmaceutical Sciences, 2015, 73: 35-43.

Yuhao Cheng, Hao Cheng, Chenxiao Jiang, Xuefeng Qiu, Kaikai Wang, Wei Huan, Ahu Yuan, Jinhui Wu & Yiqiao Hu*. Perfluorocarbon nanoparticles enhance reactive oxygen levels and tumour growth inhibition in photodynamic therapy [J]. Nature communications, 2015, 6: 8785.

Ahu Yuan, Bing Yang, Jinhui Wu, Yiqiao Hu*, Xin Ming. Dendritic nanoconjugates of photosensitizer for targeted photodynamic therapy [J]. Acta biomaterialia, 2015, 21: 63-73.

Ahu Yuan, Xiaolei Tang, Xufeng Qiu, Jiang Ke, Jinhui Wu, Yiqiao Hu*. Activatable photodynamic destruction of cancer cells by NIR dye/photosensitizer loaded liposomes. Chem Commun(2014)

Chenxiao Jiang, Hao Cheng, Ahu Yuan, Xiaolei Tang, Jinhui Wu, Yiqiao Hu*. Hydrophobic IR780 Encapsulated in Biodegradable Human Serum Albumin Nanoparticles for Photothermal and Photodynamic Therapy. Acta Biomaterialia(2014)

Tingsheng Lin, Yifan Zhang, Jinhui Wu*, Xiaozhi Zhao, Huibo Lian, Wei Wang, Hongqian Guo, Yiqiao Hu*. A Floating Hydrogel System Capable of Generating CO2Bubbles to Diminish Urinary Obstruction After Intravesical Instillation. Pharmaceutical Research. April 2014.

Lili Zhao, Ying Gao, Guoxiang Gu, Jinhui Wu*, Zhining Fan, Hong Dong and Yiqiao Hu*. Rational design of drug-eluting stents via electrospray and in vivo evaluation of preventing oesophageal stricture. RSC Adv, 2014, 4, 16885-16892.

Jinhui Wu, Chenchen Song, Chenxiao Jiang, Xin Shen, Qian Qiao, Yiqiao Hu*. Nucleolin Targeting AS1411 Modified Protein Nanoparticle for Antitumor Drugs Delivery. Molecular Pharmaceutics. 2013 Oct 7;10 (10):3555-63.