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甘卫东

领域:生物产业 学校:南京大学职称:教授

Xp11.2易位性肾癌...

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教育背景

工作经历

2003/10-2009/09,南京大学医学院附属鼓楼医院,泌尿外科,副主任医师 2009/10至今,南京大学医学院附属鼓楼医院,泌尿外科,主任医师 2011/10-2011/12,美国匹兹堡大学医学中心泌尿外科,访问学者

项目课题经历

国家自然科学基金面上项目:TFE3基因断裂和融合在Xp11.2易位性肾癌中的致病机制研究;

省自然科学基金:肿瘤抑制基因ER-β的表达变化在前列腺癌细胞信号网络中的作用分析

论文、成果、著作等

Renal Cell Carcinoma Associated with Xp11.2 Translocation/TFE3 Gene Fusions: Clinical Features, Treatments and Prognosis. PLoS One 2016; 11, e0166897. DOI:10.1371/journal.pone.0166897.

Percutaneous radiofrequency ablation for renal cell carcinoma vs. partial nephrectomy: Comparison of long-term oncologic outcomes in both clear cell and non-clear cell of the most common subtype. Urol Oncol 2017; 35, 530 e531-530 e536. DOI:10.1016/j.urolonc.2017.03.014.

PRCC-TFE3 dual-fusion FISH assay: A new method for identifying PRCC-TFE3 renal cell carcinoma in paraffin-embedded tissue. PLoS One 2017; 12, e0185337. DOI:10.1371/journal.pone.0185337.

Postoperative recurrence of adult renal cell carcinoma associated with Xp11.2 translocation/TFE3 gene fusion. J Int Med Res 2017; 45, 1287-1296. DOI:10.1177/0300060517711358.

Newly designed break-apart and ASPL-TFE3 dual-fusion FISH assay are useful in diagnosing Xp11.2 translocation renal cell carcinoma and ASPL-TFE3 renal cell carcinoma: a STARD-compliant article. Medicine (Baltimore) 2015; 94, e873. DOI:10.1097/MD.0000000000000873.

Renal cell carcinoma associated with Xp11.2 translocation/TFE3 gene fusions: clinical experience and literature review. Future Oncol 2015; 11, 3243-3252. DOI:10.2217/fon.15.177.

Pseudocapsule of renal cell carcinoma associated with Xp11.2 translocation/TFE3 gene fusion: a clue for tumor enucleation? Int J Clin Exp Pathol 2015; 8, 5403-5410.

Xp11.2 translocation renal cell carcinomas in young adults. BMC Urol 2015; 15, 57. DOI:10.1186/s12894-015-0055-0.

Dynamic Contrast-Enhanced CT Characterization of Xp11.2 Translocation/TFE3 Gene Fusions versus Papillary Renal Cell Carcinomas. Biomed Res Int 2015; 2015, 298679. DOI:10.1155/2015/298679.

Laparoscopic radiofrequency ablation-assisted enucleation of Xp11.2 translocation renal cell carcinoma: A case report. Oncol Lett 2014; 8, 1237-1239. DOI:10.3892/ol.2014.2267.

Cardiopulmonary bypass-assisted surgery for the treatment of Xp11.2 translocation/TFE3 gene fusion renal cell carcinoma with a tumor thrombus within the inferior vena cava: A case report. Oncol Lett 2015; 10, 3532-3534. DOI:10.3892/ol.2015.3739.

Xp11.2 translocation renal cell carcinoma with multiple bone metastases: A case report. Oncol Lett 2016; 11, 2233-2236. DOI:10.3892/ol.2016.4211.

专利、著作版权等

专利授权2项肾癌的荧光原位杂交多克隆分离探针及其试剂盒应用,专利号CN103952439A.

发明专利:腺泡状软组织肉瘤的基因探针及其试剂盒应用,专利号2014106380146.

实用新型专利:用于男性尿道浸润麻醉的阴茎夹,专利号201420211002.0

实用新型专利:肾脏局部血流阻断装置,专利号201420384048.2

实用新型专利:腹腔镜工作套管双重清洁和防漏气装置,专利号201420197388.4

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