现任南京总医院神经外科主任、全军神经外科研究所所长

．国家自然科学基金面上项目，Nrf2-TET交互对话调控化疗的胶质瘤焦亡的机制研究（81672503），2017.01-2020.12，总经费52万。

2．江苏省医学重点学科（实验室）建设（ZDXKB2016023），2016.01-2020.12，总经费200万。

3．国家自然科学基金面上项目，脑外伤后Nrf2-ARE通路对泛素-蛋白酶体系统的作用及机制研究（81371357），2014.01-2016.12，总经费70万。

4．江苏省临床医学科技专项，颅内动脉瘤治疗技术的规范化应用及治疗相关问题的“转化”研究（BL2013027），2013.01-2016.12，总经费200万。

5．军区重大专项NRF2-ARE信号通路对爆炸性脑损伤的保护功能研究（ZX28），2014.01-2016.12，总经费30万。

Xiangrong Chen,Handong Wang*, Mengliang Zhou, et al. Valproic acid attenuatestraumaticbrain injury-induced inflammationin vivo: involvement of autophagyand the nrf2/are signaling pathway. Frontiers in Molecular Neuroscience,2018, 11,117.

Li Zhang,Handong Wang*.Autophagy in traumatic brain injury: a new target for therapeutic intervention. Frontiers in Molecular Neuroscience 2018, 11, 190.

Y, Zhu, H. Wang*, J. Fang, et al. SS-31 Provides neuroprotection by reversing mitochondrial dysfunction after traumatic brain injury.Oxid Med Cell Longev, 2018.

Junyang Li, Xiangjun Ji,Handong Wang*. Targeting Long Noncoding RNAHMMR-AS1 Suppresses andRadiosensitizes Glioblastoma. Neoplasia Vol, 2018, 20.

Xiang Li, Handong Wang*, Guodao Wen, et al. Neuroprotection by quercetin via mitochondrial functionadaptation in traumatic brain injury: PGC-1a pathway as apotential mechanism .J. Cell. Mol. Med., 2017 .1-9.

Zhang L, Wang H*, Fan Y,et al. Fucoxanthin provides neuroprotection in models of traumatic brain injury via the Nrf2-ARE and Nrf2-autophagy pathways. Sci Rep, 2017;7:46763.

Ding H, Wang X, Wang H*, et al. Nrf2-ARE signaling provides neuroprotection in traumatic brain injury via modulation of the ubiquitin proteasome system. Neurochem Int, 2017, 111,32-34.

Zhang L, Wang H*. Targeting the NF-E2-Related Factor 2 Pathway: a Novel Strategy for Traumatic Brain Injury. Mol Neurobiol, 2017.

Li L, Pan H, Wang H*, et al. Interplay between VEGF and Nrf2 regulates angiogenesis due to intracranial venous hypertension. Scientific Reports. 2016;6:37338.

Jianguo Xu, Handong Wang*, KeDing,etal.Luteolin provides neuroprotection in models of traumatic brain injuryvia the Nrf2–ARE pathway.Free Radical Biology and Medicine 2014.71:186-95.

Ke Ding, Handong Wang*, Jianguo Xu, Tao Li, Li Zhang, Yu Ding, Lin Zhu, JinHe,MengliangZhou.Melatonin stimulates antioxidant enzymes and reduces oxidativestress in experimental traumatic brain injury: the Nrf2–ARE signalingpathway as a potential mechanism.Free Radic Biol Med. 2014.71:186-95.

Xiangjun Ji, Handong Wang*, JianhongZhu,etal.Knockdown of Nrf2 suppresses glioblastoma angiogenesisby inhibiting hypoxia-induced activation of HIF-1a.International Journal of Cancer 2014.135(3):574-84.