为南京军区总医院肿瘤内科行政副主任，南京大学、南方医科大学及南京医科大学博士生导师/博士后合作导师

主持参加国家自然科学基金5项，主持江苏省杰出青年基金1项，江苏省“333 高层次人才培养工程”第三层次培养对象1:江苏省杰出青年基金项目　2014/07-2017/07、BK20140032、新一代双靶向病毒-基因系统治疗恶性肿瘤的实验研究(100万/在研/主持)

2:国家自然科学基金面上项目2018/01-2021/12、81772995、：LncRNA-ROR/AUF-1/Aurora-A信号轴在肝细胞癌恶性生物学行为中的作用及其机制研究(55万/在研/主持)

3:国家自然科学基金面上项目2015/01-2018/12、81472266、Aurora-A/NF-kappaB/microRNA-17-92基因簇在肝细胞癌恶性生物学行为中的作用及其可能的分子机制(85万/在研/主持)

4:国家自然科学基金面上项目2012/01-2015/12、81172335、肝细胞癌中Aurora-A基因过表达的转录后水平分子调控机制研究(57万/结题/主持)

5:国家自然科学基金青年基金项目2010/01-2012/12、30901440、肝细胞癌中Aurora-A基因过表达的转录水平分子调控机制研究(20万/结题/主持)

6:国家自然科学基金应急管理项目2017/01-2017/12、81641100 81641100 、HBX/miR-129-2/Aurora-A信号轴参与调控HBV相关肝癌恶性生物学行为的分子机制研究(10万/在研/主持)

7：江苏省医学重点人才项目2017.01-2019.12，40万/主持

1: Zhi Y, Zhou H, Mubalake A, Chen Y, Zhang B, Zhang K, Chu X, Wang R(Corresponding author).Regulation andfunctionsof MicroRNA-149 in human cancers.Cell Prolif. 2018 Jul 12:e12465.

2:Chen Y, Shen Z, Zhi Y, Zhou H, Zhang K, Wang T, Feng B, Chen Y, Song H, Wang R(Corresponding author), Chu X.Long non-coding RNA ROR promotes radioresistance in hepatocelluar carcinoma cells by acting as a ceRNA for microRNA-145 to regulate RAD18 expression.Arch Biochem Biophys. 2018 May 1;645:117-125.

3: Zhang K, Chen J, Zhou H, Chen Y, Zhi Y, Zhang B, Chen L, Chu X, Wang R(Corresponding author), Zhang C. PU.1/microRNA-142-3p targets ATG5/ATG16L1 to inactivate autophagy and sensitize hepatocellular carcinoma cells to sorafenib. Cell Death Dis. 2018 Feb 22;9(3):312.

4: Li C, Lu L, Feng B, Zhang K, Han S, Hou D, Chen L, Chu X, Wang R(Corresponding author). The lincRNA-ROR/miR-145 axis promotes invasion and metastasis in hepatocellular carcinoma via induction of epithelial-mesenchymal transition by targeting ZEB2.Sci Rep. 2017 Jul 5;7(1):4637.

5: Zhang B, Han S, Feng B, Chu X, Chen L, Wang R(Corresponding author).Hepatitis B virus X protein-mediated non-coding RNA aberrations in the development of human hepatocellular carcinoma.Exp Mol Med. 2017 Feb 10;49(2):e293.

6: Pan Y, Li C, Chen J, Zhang K, Chu X, Wang R(Corresponding author), Chen L. The Emerging Roles of Long Noncoding RNA ROR (lincRNA-ROR) and its Possible Mechanisms in Human Cancers.Cell Physiol Biochem. 2016;40(1-2):219-229.

7: Gao Y, Feng B, Han S, Lu L, Chen Y, Chu X, Wang R(Corresponding author), Chen L. MicroRNA-129 in Human Cancers: from Tumorigenesis to Clinical Treatment.Cell Physiol Biochem. 2016;39(6):2186-2202.

8: Huang J, Chen Y, Li J, Zhang K, Chen J, Chen D, Feng B, Song H, Feng J, Wang R(Corresponding author), Chen L. Notch-1 Confers Chemoresistance in Lung Adenocarcinoma to Taxanes through AP-1/microRNA-451 Mediated Regulation of MDR-1.Mol Ther Nucleic Acids. 2016 Oct 11;5(10):e375.

9: Pan X, Wang R(Co-first author), Bian H, De W, Zhang P, Wei C, Wang Z. Overexpression of Inhibitor of Growth 4 Enhances Radiosensitivity in Non-Small Cell Lung Cancer Cell Line SPC-A1.Technol Cancer Res Treat. 2017 Oct;16(5):533-545.

10: Gao Y, Feng B, Han S, Zhang K, Chen J, Li C, Wang R(Corresponding author), Chen L.The Roles of MicroRNA-141 in Human Cancers: From Diagnosis to Treatment.Cell Physiol Biochem. 2016;38(2):427-48.

11: Lou J, Zhang K, Chen J, Gao Y, Wang R(Corresponding author), Chen LB. Prognostic significance of SOX-1 expression in human hepatocelluar cancer.Int J Clin Exp Pathol. 2015 May 1;8(5):5411-8.

12: Li C, Chen J, Zhang K, Feng B, Wang R(Corresponding author), Chen L. Progress and Prospects of Long Noncoding RNAs (lncRNAs) in Hepatocellular Carcinoma. Cell Physiol Biochem. 2015;36(2):423-34.

13: Feng B, Zhang K, Wang R(Corresponding author), Chen L. Non-small-cell lung cancer and miRNAs: novel biomarkers and promising tools for treatment.Clin Sci (Lond). 2015 May 1;128(10):619-34.

14: Chen D, Huang J, Zhang K, Pan B, Chen J, De W, Wang R(Corresponding author), Chen L. MicroRNA-451 induces epithelial-mesenchymal transition in docetaxel-resistant lung adenocarcinoma cells by targeting proto-oncogene c-Myc.Eur J Cancer. 2014 Nov;50(17):3050-67.

15: Chen DQ, Huang JY, Feng B, Pan BZ, De W, Wang R(Corresponding author), Chen LB. Histone deacetylase 1/Sp1/microRNA-200b signaling accounts for maintenance of cancer stem-like cells in human lung adenocarcinoma.PLoS One. 2014 Oct 3;9(10):e109578.

16: Huang JY, Cui SY, Chen YT, Song HZ, Huang GC, Feng B, Sun M, De W, Wang R(Corresponding author), Chen LB. MicroRNA-650 was a prognostic factor in human lung adenocarcinoma and confers the docetaxel chemoresistance of lung adenocarcinoma cells via regulating Bcl-2/Bax expression.PLoS One. 2013 Aug 21;8(8):e72615.

17: Cui SY, Huang JY, Chen YT, Song HZ, Huang GC, De W, Wang R(Corresponding author), Chen LB.The role of Aurora A in hypoxia-inducible factor 1α-promoting malignant phenotypes of hepatocelluar carcinoma.Cell Cycle. 2013 Sep 1;12(17):2849-66.

18: Zheng Y, Wang R(Co-first author), Song HZ, Pan BZ, Zhang YW, Chen LB.Epigenetic downregulation of RUNX3 by DNA methylation induces docetaxel chemoresistance in human lung adenocarcinoma cells by activation of the AKT pathway.Int J Biochem Cell Biol. 2013 Nov;45(11):2369-78.

19: Cui SY, Huang JY, Chen YT, Song HZ, Feng B, Huang GC, Wang R(Corresponding author)Chen LB, De W.Let-7c governs the acquisition of chemo- or radioresistance and epithelial-to-mesenchymal transition phenotypes in docetaxel-resistant lung adenocarcinoma.Mol Cancer Res. 2013 Jul;11(7):699-713.