东部战区总医院（原南京军区南京总医院）国家临床重点专科、全军临床检验医学研究所检验科主任，教授，博士生导师

2019年01月至2022年12月：“SMAD3基因启动子DNA甲基化及其下游miRNA水平联合检测作为冠心病新型分子标志物的临床价值及作用机制” 获国家自然科学基金资助（58万元）（81871702），主持

2016年01月至2019年12月：“分泌型miR-186在动脉粥样硬化性心血管疾病中的临床价值和机制研究” 获国家自然科学基金资助（65万元）（81572074），主持

2013年01月至2016年12月：“与氧化脂蛋白相关的血浆特异性microRNA在动脉粥样硬化中的作用研究”获国家自然科学基金资助（95万元）（81271904），主持

2012年10月至2016年09月：“高通量HRM分析技术在心血管疾病和胃癌的易感基因突变检测中的应用”获国家重大科学仪器设备开发专项（141万元）（2012YQ03026109），主持

2010年01月至2015年12月：“髓过氧化物酶与冠心病患者血浆特异性miRNA相关性研究” 获国家高技术研究发展计划（863计划）子课题项目（10万元）（2011AA02A111），主持

SCI论文40余篇；Lu P, Wang F, Wu J, Wang C, Yan J, Li ZL, Song JX* and Wang JJ. Elevated serum miR-7, miR-9, miR-122 and miR-141 are non-invasive biomarkers of acute pancreatitis. Disease Markers. 2017:7293459. doi: 10.1155/2017/7293459. Epub 2017 Dec 3.

Li DD#, Yan J#, Yuan YL#, Wang C, Wu J, Chen QW, Song JX*, Wang JJ**. Genome-wide DNA methylome alterations in acute coronary syndrome. International Journal of molecular medicine. Int J Mol Med.2018 Jan;41(1):220-232

Wan SJ,Wang J,Wang J,Wu J,Song JX,Zhang CY,Zhang CN,Wang C*,Wang JJ**. IncreasedserummiR-7is apromisingbiomarkerfortype2diabetesmellitusand its microvascularcomplications. DiabetesRes Clin Pract.2017 Aug;130:171-179. doi: 10.1016/j.diabres.2017.06.005. Epub 2017 Jun 11.

Bu XM,Niu DM,Wu J,Yuan YL,Song JX*,Wang JJ**. Elevated levels of preβ1-high-densitylipoproteinareassociatedwithcholesterolestertransferprotein, the presenceandseverityofcoronaryarterydisease. Lipids Health Dis.2017 Jan 10;16(1):4. doi: 10.1186/s12944-016-0394-1.

Wu J, Fan CL, Ma LJ, Liu T, Wang C, Song JX, Lv QS, Pan H, Zhang CN, Wang JJ*. Distinctive expression signatures of serum microRNAs in ischaemic stroke and transient ischaemic attack patients. Thromb Haemost. 2017 May 3;117(5):992-1001.

Wang C, Wu C, Yang Q, Ding M, Zhong J, Zhang CY, Ge J*, Wang J**, Zhang C***. miR-28-5p acts as a tumor suppressor in renal cell carcinoma for multiple antitumor effects by targeting RAP1B. Oncotarget. 2016 Oct 7; 7(45): 73888-73902.

Wang C, Wan SJ, Yang T, Niu DM, Zhang AS, Yang CH, Cai JL,Wu J, SongJX, Zen K, Zhang CY, Zhang CN and Wang JJ**. Increased serum microRNAs are closely associated with the presence of microvascular complications in type 2 diabetes mellitus. Sci Rep, 2016, Feb 1;6:20032. doi: 10.1038/srep20032（5.228）

Yang T,Song JX,Bu XM,Wang C,Wu J,Cai JL,Wan SJ,Fan CL,Zhang CN,Wang JJ**, ElevatedserummiR-93,miR-191andmiR-499arenoninvasivebiomarkersfor the presence and progressionoftraumaticbraininjury. J Neurochem.2016 Apr;137(1):122-9. 4.28

Wang C, Hu JC, Lu ML, Gu HW, Zhou XJ, Chen X, Zen K, Zhang CY, Zhang TH, Ge JP, Wang JJ*, Zhang CN**,. A panel of five serum miRNAs as a potential diagnostic tool for early-stage renal cell carcinoma. Sci Rep, 2015, 5:7610. 5.578

Yu R, Yuan YL, Niu DM, Song JX, Liu T, Wu J, Wang JJ*. Elevated beta2-glycoprotein I-low-density lipoprotein levels are associated with the presence of diabetic microvascular complications. J Diabetes Complications, 2015, 29(1):59-63.

Wu J, Song JX, Wang C, Niu DM, Li HQ, Liu YX, Ma LJ, Yu RJ, Chen X, Zen K, Yang Q, Zhang CN, Zhang CY, Wang JJ*, Identification of serummicroRNAs for cardiovascular risk stratification in dyslipidemia subjects, Int J Cardiol, 172(1), 2014, 232-234.

Yu RJ, Song JX, Wu J, Niu DM, Ma LJ, Zong C, Ju HX , Wang JJ *.A sensitive chemiluminescence imaging immunoassay for simultaneous detection of serum oxidized lipoprotein(a) and low density lipoprotein. Clin Chem Lab Med, 2014, 52(6):869-77.

Ma LJ, Wu J, Niu DM, Yu RJ, Song JX, Zhang CN, Wang JJ*, Serum lipoprotein(a) complexes with beta2-glycoprotein I levels in patients with ischemic stroke. Clin Chim Acta, 2014,429, 163-167.