教育背景
1982-1997年于第二军医大学军医系学习,获学士学位;1987-1990上海第二医科大学硕士研究生,获硕士学位;2001-2004南京大学医学院博士研究生,获博士学位
工作经历
1990-至今一直在南京军区南京总医院神经外科工作。2007年起任南京军区南京总医院神经外科副主任,2013年起任全军神经外科研究所副所长、脑血管病外科治疗中心主任。2007-2009年分别被聘为南京大学、南方医科大学和上海第二军医大学博士生导师,2014年被聘为南京医科大学博士生导师
项目课题经历
主持参加国家自然科学基金项目3项,承担国家科技支撑计划项目(子课题)3项,江苏省自然科学基金项目3项,其它科研项目包括江苏省六大人才高峰课题、江苏省“333”人才培养基金课题、江苏省医学重点人才基金课题、南京军区医药卫生科研重点课题等
1.国家自然科学基因面上项目(81371294) 高迁移率族蛋白1 在蛛网膜下腔出血后脑损伤中作用机制(2014.01-2016.12)
2.国家自然科学基金面上项目 (81171170) 创伤性脑损伤后不同时期脑内核因子-κB双向作用的实验研究 (2012.01-2015.12)
3.江苏省自然科学基金面上项目(BK20141375) 糖基化终末产物受体在蛛网膜下腔出血后脑损伤中的作用机制研究(2015.01-2017.06)
4.国家“十二五”科技支撑计划课题(子课题) 脑动脉瘤微创治疗时机及治疗方案优化研究(2011.09-2015.12)
5.全军后勤科研重点项目 战创伤致开放性损伤的创面保护技术及仿生脑膜的研究 (2015.01-2019.12)
论文、成果、著作等
发表学术论文130余篇fluid concentrations of asymmetric dimethylarginine correlate with adverse clinical outcome in subarachnoid hemorrhage patients. J Clin Neurosci, 2014.
2.Li H, Zhang X, Zhang QR, Hang CH, Resolution of Migraine-Like Headache by Coil Embolization of a Primitive Trigeminal Artery Aneurysm. Pain Med, 2014.
3.Li S, Zhu JH, Cao LP, Sun Q, Liu HD, Li WD, Li JS, Hang CH, Growth inhibitory in vitro effects of glycyrrhizic acid in U251 glioblastoma cell line. Neurol Sci, 2014.
4.Li H, Wu W, Sun Q, Liu M, Li W, Zhang XS, Zhou ML, Hang CH, Expression and cell distribution of receptor for advanced glycation end-products in the rat cortex following experimental subarachnoid hemorrhage. Brain Res, 2014. 1543: p. 315-23.
5.Li WD, Sun Q, Zhang XS, Wang CX, Li S, Li W, Hang CH, Expression and cell distribution of neuroglobin in the brain tissue after experimental subarachnoid hemorrhage in rats: a pilot study. Cell Mol Neurobiol, 2014. 34(2): p. 247-55.
6.Hu YC, Sun Q, Li W, Zhang DD, Ma B, Li S, Li WD, Zhou ML, Hang CH, Biphasic activation of nuclear factor kappa B and expression of p65 and c-Rel after traumatic brain injury in rats. Inflamm Res, 2014. 63(2): p. 109-15.
7.Li W, Ling HP, You WC, Liu HD, Sun Q, Zhou ML, Shen W, Zhao JB, Zhu L, Hang CH, Elevated cerebral cortical CD24 levels in patients and mice with traumatic brain injury: a potential negative role in nuclear factor kappa b/inflammatory factor pathway. Mol Neurobiol, 2014. 49(1): p. 187-98.
8.Sun Q, Wang F, Li W, Li W, Hu YC, Li S, Zhu JH, Zhou M, Hang CH, Glycyrrhizic acid confers neuroprotection after subarachnoid hemorrhage via inhibition of high mobility group box-1 protein: a hypothesis for novel therapy of subarachnoid hemorrhage. Med Hypotheses, 2013. 81(4): p. 681-5.
9.Liu HD, Li W, Chen ZR, Hu YC, Zhang DD, Shen W, Zhou ML, Zhu L, Hang CH, Expression of the NLRP3 inflammasome in cerebral cortex after traumatic brain injury in a rat model. Neurochem Res, 2013. 38(10): p. 2072-83.
10.Sun Q, Dai Y, Zhang X, Hu YC, Zhang D, Li W, Zhang XS, Zhu JH, Zhou ML, Hang CH, Expression and cell distribution of myeloid differentiation primary response protein 88 in the cerebral cortex following experimental subarachnoid hemorrhage in rats: a pilot study. Brain Res, 2013. 1520: p. 134-44.
11.Hu YC, Wang F, Zhang DD, Sun Q, Li W, Dai YX, Zhou ML, Hang CH, Expression of intestinal CD40 after experimental traumatic brain injury in rats. J Surg Res, 2013. 184(2): p. 1022-7.
12.Zhao J, Zhang M, Li W, Su X, Zhu L, Hang C, Suppression of JAK2/STAT3 signaling reduces end-to-end arterial anastomosis induced cell proliferation in common carotid arteries of rats. PLoS One, 2013. 8(3): p. e58730.
13.Zhang D, Hu Y, Sun Q, Zhao J, Cong Z, Liu H, Zhou M, Li K, Hang C, Inhibition of transforming growth factor beta-activated kinase 1 confers neuroprotection after traumatic brain injury in rats. Neuroscience, 2013. 238: p. 209-17.
14.Li W, Liu HD, You WC, Zhou ML, Ling HP, Shen W, Zhu L, Hang CH, Enhanced cortical expression of myeloid differentiation primary response protein 88 (Myd88) in patients with traumatic brain injury. J Surg Res, 2013. 180(1): p. 133-9.
15.Liu HD, Li W, Chen ZR, Zhou ML, Zhuang Z, Zhang DD, Zhu L, Hang CH, Increased expression of ferritin in cerebral cortex after human traumatic brain injury. Neurol Sci, 2013. 34(7): p. 1173-80.
16.Li W, Ling HP, You WC, Ji XJ, Tang Y, Zhao JB, Su XF, Hang CH, Recombinant high-mobility group box 1 protein (HMGB-1) promotes myeloid differentiation primary response protein 88 (Myd88) upregulation in mouse primary cortical neurons. Neurol Sci, 2013. 34(6): p. 847-53.
17.Ling HP, Li W, Zhou ML, Tang Y, Chen ZR, Hang CH, Expression of intestinal myeloid differentiation primary response protein 88 (Myd88) following experimental traumatic brain injury in a mouse model. J Surg Res, 2013. 179(1): p. e227-34.
18.Zhao J, Li G, Zhang Y, Su X, Hang C, The potential role of JAK2/STAT3 pathway on the anti-apoptotic effect of recombinant human erythropoietin (rhEPO) after experimental traumatic brain injury of rats. Cytokine, 2011. 56(2): p. 343-50.
19.Zhao JB, Zhang Y, Li GZ, Su XF, Hang CH, Activation of JAK2/STAT pathway in cerebral cortex after experimental traumatic brain injury of rats. Neurosci Lett, 2011. 498(2): p. 147-52.
20.Li GZ, Zhang Y, Zhao JB, Wu GJ, Su XF, Hang CH, Expression of myeloid differentiation primary response protein 88 (Myd88) in the cerebral cortex after experimental traumatic brain injury in rats. Brain Res, 2011. 1396: p. 96-104.
21.Chen G, Zhang S, Shi J, Ai J, Qi M, Hang C, Simvastatin reduces secondary brain injury caused by cortical contusion in rats: possible involvement of TLR4/NF-kappaB pathway. Exp Neurol, 2009. 216(2): p. 398-406.
22.Chen G, Shi J, Hu Z, Hang C, Inhibitory effect on cerebral inflammatory response following traumatic brain injury in rats: a potential neuroprotective mechanism of N-acetylcysteine. Mediators Inflamm, 2008. 2008: p. 716458.
23.Chen G, Shi J, Jin W, Wang L, Xie W, Sun J, Hang C, Progesterone administration modulates TLRs/NF-kappaB signaling pathway in rat brain after cortical contusion. Ann Clin Lab Sci, 2008. 38(1): p. 65-74.
24.Chen G, Shi JX, Qi M, Wang HX, Hang CH, Effects of progesterone on intestinal inflammatory response, mucosa structure alterations, and apoptosis following traumatic brain injury in male rats. J Surg Res, 2008. 147(1): p. 92-8.
25.Chen G, Shi J, Ding Y, Yin H, Hang C, Progesterone prevents traumatic brain injury-induced intestinal nuclear factor kappa B activation and proinflammatory cytokines expression in male rats. Mediators Inflamm, 2007. 2007: p. 93431.
26.Hang CH, Shi JX, Sun BW, Li JS, Apoptosis and functional changes of dipeptide transporter (PepT1) in the rat small intestine after traumatic brain injury. J Surg Res, 2007. 137(1): p. 53-60.
27.Hang CH, Chen G, Shi JX, Zhang X, Li JS, Cortical expression of nuclear factor kappaB after human brain contusion. Brain Res, 2006. 1109(1): p. 14-21.
28.Hang CH, Shi JX, Li JS, Wu W, Yin HX, Concomitant upregulation of nuclear factor-kB activity, proinflammatory cytokines and ICAM-1 in the injured brain after cortical contusion trauma in a rat model. Neurol India, 2005. 53(3): p. 312-7.
29.Hang CH, Shi JX, Li JS, Li WQ, Wu W, Expressions of intestinal NF-kappaB, TNF-alpha, and IL-6 following traumatic brain injury in rats. J Surg Res, 2005. 123(2): p. 188-93.
30.Hang CH, Shi JX, Li JS, Li WQ, Yin HX, Up-regulation of intestinal nuclear factor kappa B and intercellular adhesion molecule-1 following traumatic brain injury in rats. World J Gastroenterol, 2005. 11(8): p. 1149-54.
31.Hang CH, Shi JX, Tian J, Li JS, Wu W, Yin HX, Effect of systemic LPS injection on cortical NF-kappaB activity and inflammatory response following traumatic brain injury in rats. Brain Res, 2004. 1026(1): p. 23-32.
32.Hang CH, Shi JX, Li JS, Wu W, Li WQ, Yin HX, Levels of vasoactive intestinal peptide, cholecystokinin and calcitonin gene-related peptide in plasma and jejunum of rats following traumatic brain injury and underlying significance in gastrointestinal dysfunction. World J Gastroenterol, 2004. 10(6): p. 875-80.
33.Hang CH, Shi JX, Li JS, Wu W, Yin HX, Alterations of intestinal mucosa structure and barrier function following traumatic brain injury in rats. World J Gastroenterol, 2003. 9(12): p. 2776-81.
专利、著作版权等
声明:本站专家信息来源于各高校官网。