教育背景
1993-1998年毕业于第二军医大学外科学,获硕士、博士学位。
1983-1988年,毕业于第一军医大学,获学士学
工作经历
2013年起,国家教育部“长江学者”特聘教授。
2013年起,全军普通外科研究重症胰腺炎中心主任
2011年起,南京军区总医院 重症医学中心主任
2008年起,任南京大学医学院教授、博士研究生导师。
2003年, 澳大利亚墨尔本大学Austin医院ICU进修
2002-2008年,任南京大学医学院副教授、硕士研究生导师。
1998年起,历任南京军区总医院外科ICU主治医师、副主任医师/主任医师
1988 -1993年任南京军区总医院住院医
项目课题经历
1、2012-2015 “重症急性胰腺炎多中心临床研究” 江苏省科技厅临床医学科技专项(项目编号:BL2012006) 主持 709万
2、2011-2015 “重症急性胰腺炎早期控制交感神经兴奋性对炎症反应和器官功能的影响” 江苏省“十二五”重点医学人才项目(项目编号:RC2011127) 主持 100万
3、2011-2015 “自主神经兴奋性调节对重症急性胰腺炎早期炎症反应和器官功能的影响” 国家自然科学基金(项目编号:81170438) 主持 50万
4、2009-2014 “重症急性胰腺炎腹腔高压对肠粘膜屏障的损伤机理和防治研究”南京军区卫生部重点项目(通知文件号:[2010]681号) 主持 25万
5、2009-2012 “肠粘膜屏障损伤、菌群失衡与细菌易位形成”国家自然科学基金重点项目(项目编号:30830098) 分课题负责人 160万
6、2007-2011 “脓毒症病人肠粘膜屏障损伤的机理和防治研究”江苏省“十一五”重点医学人才项目(项目编号:RC2007120) 主持 100万
7、2006-2010 “创伤后肠粘膜屏障损伤的机理和防治研究”军队“11.5”重点攻关项目(项目编号:06G041) 主持 30万
论文、成果、著作等
.Ke, L., Calzavacca, P., Bailey, M., May, C. N., Li, W. Q., Bertolini, J., & Bellomo, R. (2014). Systemic and renal haemodynamic effects of fluid bolus therapy: sodium chloride versus sodium octanoate-balanced solution. Crit Care Resusc, 16(1), 29-33.
2.Ke, L., Ni, H. B., Tong, Z. H., Li, W. Q., Li, N., & Li, J. S. (2014). Efficacy of Continuous Regional Arterial Infusion With Low Molecular Weight Heparin for Severe Acute Pancreatitis in a Porcine Model. Shock.
3.Lu, J., Liao, L. M., Geng, Y. X., Wang, X., Tong, Z. H., Ke, L., . . . Li, J. S. (2014). A double-blind, randomized, controlled study to explore the efficacy of rFVIIa on intraoperative blood loss and mortality in patients with severe acute pancreatitis. Thromb Res, 133(4), 574-578.
4.Wu, C., Ke, L., Tong, Z., Li, B., Zou, L., Li, W., . . . Li, J. (2014). Hypertriglyceridemia is a Risk Factor for Acute Kidney Injury in the Early Phase of Acute Pancreatitis. Pancreas.
5.Zhang, L., Zhou, J., Ke, L., Nie, Y., Tong, Z., Li, W., & Li, J. (2014). Role of heart rate variability in predicting the severity of severe acute pancreatitis. Dig Dis Sci, 59(10), 2557-2564.
6.Zheng, Y. S., Wu, Z. S., Ni, H. B., Ke, L., Tong, Z. H., Li, W. Q., Li, J. S. (2014). Codonopsis pilosula polysaccharide attenuates cecal ligation and puncture sepsis via circuiting regulatory T cells in mice. Shock, 41(3), 250-255.
7.Zou, L., Ke, L., Li, W., Tong, Z., Wu, C., Chen, Y., Li, J. (2014). Enteral nutrition within 72 h after onset of acute pancreatitis vs delayed initiation. Eur J Clin Nutr.
8.Geng, Y., Li, W., Sun, L., Tong, Z., Li, N., & Li, J. (2011). Severe acute pancreatitis during pregnancy: eleven years experience from a surgical intensive care unit. Dig Dis Sci, 56(12), 3672-3677.
9.Ke, L., Ni, H. B., Lu, J., Tong, Z. H., Ding, W. W., Li, W. Q., & Li, J. S. (2011). Postoperative thrombocytosis in patients with pancreatic necrosis: is it an occasional phenomenon? Pancreas, 40(1), 161-163.
10.Ke, L., Ni, H. B., Sun, J. K., Tong, Z. H., Li, W. Q., Li, N., & Li, J. S. (2012). Risk factors and outcome of intra-abdominal hypertension in patients with severe acute pancreatitis. World J Surg, 36(1), 171-178.
11.Ke, L., Ni, H. B., Tong, Z. H., Li, W. Q., Li, N., & Li, J. S. (2011). Intra-abdominal pressure and abdominal perfusion pressure: which is a better marker of severity in patients with severe acute pancreatitis. J Gastrointest Surg, 15(8), 1426-1432. 5.Ke, L., Ni, H. B., Tong, Z. H., Li, W. Q., Li, N., & Li, J. S. (2012). D-dimer as a marker of severity in patients with severe acute pancreatitis. J Hepatobiliary Pancreat Sci, 19(3), 259-265.
12.Ke, L., Ni, H. B., Tong, Z. H., Li, W. Q., Li, N., & Li, J. S. (2013). The importance of timing of decompression in severe acute pancreatitis combined with abdominal compartment syndrome. J Trauma Acute Care Surg, 74(4), 1060-1066.
13.Ke, L., Tong, Z. H., Ni, H. B., Ding, W. W., Sun, J. K., Li, W. Q., Li, J. S. (2012). The effect of intra-abdominal hypertension incorporating severe acute pancreatitis in a porcine model. PLoS One, 7(3), e33125.
14.Ni, H. B., Ke, L., Sun, J. K., Tong, Z. H., Ding, W. W., Li, W. Q., Li, J. S. (2012). Beneficial effect of hypertonic saline resuscitation in a porcine model of severe acute pancreatitis. Pancreas, 41(2), 310-316.
15.Sun, J. K., Li, W. Q., Ke, L., Tong, Z. H., Ni, H. B., Li, G., Li, J. S. (2013). Early enteral nutrition prevents intra-abdominal hypertension and reduces the severity of severe acute pancreatitis compared with delayed enteral nutrition: a prospective pilot study. World J Surg, 37(9), 2053-2060.
16.Sun, J. K., Li, W. Q., Ni, H. B., Ke, L., Tong, Z. H., Li, N., & Li, J. S. (2013). Modified gastrointestinal failure score for patients with severe acute pancreatitis. Surg Today, 43(5), 506-513.
17.Sun, J. K., Mu, X. W., Li, W. Q., Tong, Z. H., Li, J., & Zheng, S. Y. (2013). Effects of early enteral nutrition on immune function of severe acute pancreatitis patients. World J Gastroenterol, 19(6), 917-922.
18.Sun, L., Li, W., Geng, Y., Shen, B., & Li, J. (2011). Acute pancreatitis in pregnancy. Acta Obstet Gynecol Scand, 90(6), 671-676.
19.Tong, Z., Li, W., Yu, W., Geng, Y., Ke, L., Nie, Y., Li, J. (2012). Percutaneous catheter drainage for infective pancreatic necrosis: is it always the first choice for all patients? Pancreas, 41(2), 302-305.
20.Tong, Z., Yu, W., Ke, L., Wu, C., Li, W., Ni, H., Li, J. (2013). Acute cholecystitis in the late phase of severe acute pancreatitis: a neglected problem. Pancreas, 42(3), 531-536.
21. Zhihui T, Wenkui Y, Weiqin L, Zhiming W, Xianghong Y, Ning L, Jieshou L. A(2009).randomised clinical trial of transnasal endoscopy versus fluoroscopy for theplacement of nasojejunal feeding tubes in patients with severe acute pancreatitis. Postgrad Med J. 2009 Feb;85(1000):59-63.
22. Tong Z, Li W, Wang X, Ye X, Li N, Li J.(2010). Duodenal perforation due to a kink in a nasojejunal feeding tube in a patient with severe acute pancreatitis: a case report. J Med Case Rep. 2010 May 28;4:162.
23.Li, W., Yan, X., Wang, H., Zhang, Z., Yu, W., Ji, D., Li, J. (2007). Effects of continuous high-volume hemofiltration on experimental severe acute pancreatitis in pigs. Pancreas, 34(1), 112-119. doi: 10.1097/01.mpa.0000240605.03441.1f
24.Yan, X. W., Li, W. Q., Wang, H., Zhang, Z. H., Li, N., & Li, J. S. (2006). Effects of high-volume continuous hemofiltration on experimental pancreatitis associated lung injury in pigs. Int J Artif Organs, 29(3), 293-302.
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