1984进入南京大学生物学系学习至1994毕业，分别获得学士、硕士、博士学位

1996年到1998年于香港科技大学做博士后。1999年6月到2000年5月在美国耶鲁大学医学院做博士后。2001、2002及2004年到美国匹兹堡大学医学院做短期访问。1994-2008年在南京师范大学生生命科学院任教授。2008年调入南京大学工作至今

主持科技支撑计划项目“建立基因工程小鼠模型新品系”1项，参与973课题1项

在研国自然重点项目“蛋白质异戊二烯化调控初级/次级卵泡转换的作用与机制研究”

面上项目“睾丸支持细胞蛋白质异戊二烯化通过影响血睾屏障的结构与功能调节精子发生的机制研究”

Liu J#, Jiang S#, Zhao Y#, Sun Q, Zhang J, Shen D, Wu J, Shen N, Fu X, Sun X, Yu D,Chen J, He J, Shi T, Ding Y, Fang L, Xue B*, Li C*. Geranylgeranyl diphosphate synthase(GGPPS) regulates non-alcoholic fatty liver disease (NAFLD)-fibrosis progression bydetermining hepatic glucose/fatty acid preference under high-fat diet conditions. JPathol. 2018 Nov;246(3):277-288. (Commentary by Fullerton MD. Does prenylationpredict progression in NAFLD? J Pathol. 2018; Oct 30)

Chen Z, Xu N, Chong D, Guan S, Jiang C, Yang Z, Li C.*. Geranylgeranyl pyrophosphatesynthase facilitates the organization of cardiomyocytes during mid-gestationthrough modulating protein geranylgeranylation in mouse heart. CardiovascRes. 2018 Jun 1;114(7):965-978. (Commentary by Helen M. Phillips. Proteingeranygeranylation: a possible new player in congenital heart defects. CardiovascRes. 2018;114:922-924)

Chen Jiang#, Fan Diao#, et al., Chao-Jun Li*. GGPP-mediated proteingeranylgeranylation in oocyte is essential for the establishment of oocyte- granulosacell communication and primary-secondary follicle transition in mouse ovary. PLoSGenetics, 2017, 13(1): e1006535.

Shan-Shan Lai,et al., Xiang Gao*, Chao-Jun Li*, Bin Xue* PP2Acα Positively RegulatesMice Liver Regeneration Termination through AKT/GSK3β/Cyclin D1 Pathway. JHepatology 2016, 64(2):352-360

Shan Jiang#, Di Shen#, et al., Bin Xue*, and Chao-Jun Li*. GGPPS mediatedRab27A geranylgeranylation regulates β-cell dysfunction during type 2 diabetesdevelopment via affecting insulin granule docked pool formation. J Pathol, 2016;238: 109-119. (Commentary by Kowluru A. A lack of "glue" misplaces Rab27A tocause islet dysfunction in diabetes. J Pathol. 2016; 238: 375–377)

Xiu-Xing Wang, et al., Xiang Gao*, Chao-Jun Li*. The protein prenylation alterationin Sertoli cells is associated with adult infertility resulted from childhood Mumpsinfection. J Exp Med. 2013, 210(8):1559-1574.