1987.8-1992.7 扬州大学医学院附属苏北医院 住院医师 1995.12-2000.7 扬州大学医学院附属苏北医院 主治医师 2000.7-2001.5 扬州大学医学院附属苏北医院 副主任医师 2001.5-2006.12 南京大学医学院附属鼓楼医院 副主任医师/副教授 2007.01-2009.12 南京大学医学院附属鼓楼医院 主任医师 2009.12-至今 南京大学医学院附属鼓楼医院 主任医师/教授、博导

参加国家重点基础研究发展计划（973项目）项目1项，主持江苏省“十二五科技兴卫工程”创新团队和领军人才项目1项，江苏省临床医学科技专项1项和江苏省自然科学基金项目2项 1、国家自然科学基金面上项目：半胱氨酸蛋白酶CAPN7影响子宫内膜异位症胚胎植入的机制研究，32万，结题。(No.81070492)

2、江苏省医学领军人才项目：提高体外受精-胚胎移植技术临床成功率的个体化综合策略研究，300万，在研。（LJ201102）

3、江苏省自然科学基金项目：乙酰转移酶p/CAF影响子宫内膜异位症胚胎着床的机制研究，8万，结题。(NO.BK2009038)

4、江苏省“六大人才高峰”项目：半胱氨酸蛋白酶CAPN7影响子宫膜异位症胚胎粘附和侵入的机制研究，3万，在研。(No.2010-WS-058)

5、江苏省妇幼重点学科项目，30万，在研。（FXK 201301）014.01-2016.12

6、江苏省妇幼重点人才项目：准确评估胚胎着床潜能的方法建立与临床应用， 在研。F201318） 2014.01-2016.12

7、江苏省第四期“333高层次人才培养工程”项目：锌指蛋白KLF12调控胚胎种植的机制研究，5万，在研。2014.01-2016.12

8、江苏省临床医学科技专项--重点病种的规范化诊疗研究：难治性不孕症患者辅助生育技术规范化治疗方案研究，400万，在研。（BL2014003）2014.07-2017.06

9、江苏省自然科学基金项目：输卵管积水增加miR-145调控子宫内膜间质细胞蜕膜化的分子机制研究，10万，在研。(NO.BK20141087)

发表论文100余篇，其中SCI论文近30篇 .Yan GJ, Yu F, Wang B, Zhou HJ, Ge QY, Su J, Hu YL, Sun HX*, Ding LJ*. MicroRNA miR-302 inhibits the tumorigenicity of endometrial cancer cells by suppression of Cyclin D1 and CDK1. Cancer Lett. 2014 Apr 1;345(1):39-47. (SCI IF=5.016)

* Co-Corresponding author

2．Jiang Y, Yan G, Zhang H, Shan H, Kong C, Yan Q, Xue B, Diao Z, Hu Y*, Sun H*. Activation of matrix metalloproteinase-26 by HOXA10 promotes embryo adhesion in vitro. Biochem Biophys Res Commun. 2014;445(3):622-8.（SCI IF=2.548）

* Co-Corresponding author

3. Zhu LH,Sun LH,Hu YL,Jiang Y,Liu HY,Shen XY,Jin XY,Zhen X,Sun HX*,Yan GJ*. PCAFImpairs Endometrial Receptivity and Embryo Implantation by Down-Regulating β3-Integrin Expression via HOXA10Acetylation. J Clin Endocrinol Metab.2013;98(11):4417-28. （SCI IF=6.43） *Co-Corresponding author

4. Yan G, Qin Q, Yi B, Chuprun K, Sun H, Huang S, Sun J. Protein-L-isoaspartate (D-aspartate) O-methyltransferase protects cardiomyocytes against hypoxia induced apoptosis through inhibiting proapoptotic kinase Mst1. Int J Cardiol. 2013 Oct 9;168(4):3291-9.( SCI IF=5.09)

5. Zhang Q, Sun HX, Jiang Y, Ding LJ, Wu SG, Fang T, Yan GJ, Hu YL. MicroRNA-181a Suppresses Mouse Granulosa Cell Proliferation by Targeting Activin Receptor IIA. PLoS One. 2013; 8(3):e59667.( SCI IF=4.092)

6. Anyi Dai, Haixiang Sun, Ting Fang, Qun Zhang, Shaogen Wu, Yue Jiang, Lijun Ding, Guijun Yan, Yali Hu. MicroRNA-133b Stimulates Ovarian Estradiol Synthesis by Targeting Foxl2. FEBS Lett. 2013;587(15):2474-82. (SCI IF=3.538)

7. Li R, Yan G, Zhang Q, Jiang Y, Sun H, Hu Y, Sun J, Xu B. miR-145 inhibits isoproterenol-induced cardiomyocyte hypertrophy by targeting the expression and localization of GATA6. FEBS Lett , 2013; 587(12): 1754-1761. (SCI IF=3.538)

8. Shen XY, Hu YL, Jiang Y, Liu HY, Zhu LH, Jin XY, Shan HZ, Zhen X, Sun LH*, Yan GJ*, Sun HX. Krüppel-like factor 12 negatively regulates human endometrial stromal cell decidualization. Biochem Biophys Res Commun. 2013, 29;433(1):11-7. （SCI IF=2.548）*Co-Corresponding author

9. Liu H, Jiang Y, Jin X, Zhu L, Shen X, Zhang Q, Wang B, Wang J, Hu Y, Yan G*, Sun H*. CAPN 7 promotes the migration and invasion of human endometrial stromal cell by regulating matrix metalloproteinase 2 activity. Reprod Biol Endocrinol. 2013;11:64. （SCI IF=2.144）* Co-Corresponding author

10. He QY, Ding LJ, Sun HX, Dai AY, Yan GJ, Wang B, Hu YL. FSH modulates the expression of inhibin-α and the secretion of Inhibins via orphan nuclear receptor Nur77 in ovarian granulosa cells. Mol Reprod Dev. 2013 ;80(9):734-43.（SCI IF=2.812）

11. Ding LJ, Wang B, Shen XY, Yan GJ, Zhang NY, Hu YL, Sun HX*. Withdrawal of GnRH agonist decreases oestradiol andVEGFconcentrations in high responders. Reprod Biomed Online. 2013 ;27(2):131-9.（SCI IF=2.675）Corresponding author


12.H Sun, D Zeng, R Li, R Pang, H Yang, Y Hu, Q Zhang, Y Jiang, L Huang, Y Tang, G Yan, Ji Zhou. Essential role of microRNA-155 in regulating endothelium- dependent vasorelaxation by targeting endothelial nitric oxide synthase. Hypertension. 2012; 60(6):1407-14.（SCI IF=6.207）

13. Li X*, Sun H*, Lin N, Hou X, Wang J, Zhou B, Xu P, Xiao Z, Chen B, Dai J, Hu Y. Regeneration of uterine horns in rats by collagen scaffolds loaded with collagen-binding human basic fibroblast growth factor. Biomaterials. 2011;32(32):8172-81. (*equally contributed，SCI IF=7.404)

14. Dai A, Yan G, He Q, Jiang Y, Zhang Q, Fang T, Ding L, Sun J, Sun H*, Hu Y*. Orphan nuclear receptor nur77 regulates androgen receptor gene expression in mouse ovary. PLoS One. 2012;7(6):e39950. （Co-Corresponding author，SCI IF=4.092）

15. Yan G, Zhang L, Fang T, Zhang Q, Wu S, Yue J, Sun H*, Hu Y*. MicroRNA-145 suppresses mouse granulosa cell proliferation by targeting activin receptor IB. FEBS Lett. 2012;586(19):3263-3270 （Co-Corresponding author，SCI IF=3.538）

16. Jiang Y, Hu YL, Zhao J, Zhen X, Yan GJ*, Sun HX*. The orphan nuclear receptor Nur77 regulates decidual prolactin expression in human endometrial stromal cells. Biochemical and Biophysical Research Communications. 2011;404 (2):628-33（Co-Corresponding author，SCI IF=2.595）

17. Ding LJ, Yan GJ, Ge QY, Yu F, Zhao X, Diao ZY, Wang ZQ, Yang ZZ, Sun HX*, Hu YL*. FSH acts on the proliferation of type A spermatogonia via Nur77 that increases GDNF expression in the Sertoli cells. FEBS Lett. 2011;585(15):2437-44. （Co-Corresponding author，SCI IF=3.538）

18. Sun H, Chen LJ, Yan GJ, Wang R, Diao ZY, Hu YL, Li CJ，HOXA10 suppresses p/CAF promoter activity via three consecutive TTAT units in human endometrial stromal cells. Biochemical and Biophysical Research Communications.2009；379 :16–21 （SCI IF=2.595）

19. Zhang X, Ding L, Diao Z, Yan G, Sun H, Hu Y. CYR61 Modulates the Vascular Endothelial Growth Factor C Expression of Decidual NK Cells Via PI3K/AKT Pathway. Am J Reprod Immunol. 2012; 67(3):216-23. （SCI IF=3.05）

Zhang X，Yan G, Diao Z, Sun H, Hu Y. NUR77 inhibits the expression of TIMP2 and increases the migration and invasion of HTR-8/SVneo cells induced by CYR61.Placenta. 2012;33(7):561-7. （SCI IF=3.693）

20. Dai Y, Diao Z, Sun H, Li R, Hu Y.. MicroRNA-155 is involved in the remodelling of human-trophoblast-derived HTR-8/SVneo cells induced by lipopolysaccharides. Hum Reprod. 2011; 26(7):1882-91. （SCI IF=4.475）

21. Li R, Yan G, Li Q, Sun H, Hu Y, Sun J, Xu B. MicroRNA-145 Protects Cardiomyocytes Against Hydrogen Peroxide (H2O2)-induced Apoptosis Through Targeting The Mitochondria Apoptotic Pathway. PLoS One. 2012;7(9): e44907. （SCI IF=4.092）

22. Zhou JJ, Wang ZQ, Zhao X, Wang JX, Sun HX, Hu YL . An increase of Treg cells in the peripheral blood is associated with a better in vitro fertilization treatment outcome. AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY. 2012; 68(2):100-106. (SCI IF=3.05)

23. Dai YM, Diao ZY, Sun HX, Li RT, Qiu ZH, Hu YL. MicroRNA-155 is involved in the remodelling of human-trophoblast-derived HTR-8/SVneo cells induced by lipopolysaccharides. HUMAN REPRODUCTION. 2011; 26(7): 1882-1891. (SCI IF=4.475)

24. Sun J, Fan HJ, Che YN, Cao YX, Wu XK, Sun HX, Liang FJ, Yi L, Wang Y. Association between ACE gene I/D polymorphisms and hyperandrogenism in women with Polycystic Ovary Syndrome (PCOS) and controls. BMC MEDICAL GENETICS. 2009; 10:64. (SCI IF=2.328)