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周正扬

领域:生物产业 学校:南京大学职称:

1、肿瘤和淋巴结病变的分子和功能MR成像研究 2、自身免疫性疾病的分子和功能MR成像研究...

具体了解该专家信息,请致电:027-87555799 邮箱 haizhi@uipplus.com

教育背景

苏州大学医学院硕士,南京大学医学院博士

工作经历

南京大学医学院教授,博士生导师

项目课题经历

国家自然科学基金面上项目(项目编号:81871410):荧光导航下双靶向纳米粒子介导的光热&Tregs清除治疗对胃癌转移淋巴结免疫抑制微环境的调控
主持国家自然科学基金面上项目三项,省部级基金四项
国家自然科学基金面上项目(项目编号:81671751):胃癌转移淋巴结微环境响应性诊疗一体化智能探针构建及术中荧光导航下精准光热治疗

江苏省自然科学基金面上项目(项目编号:BK20171118):胃癌转移淋巴结微环境响应性诊疗一体化智能探针的构建及术中荧光导航下光热治疗的实验研究

江苏省省重点研发计划(项目编号:BE2015605)基于HER-2抗体修饰负载阿霉素的金纳米笼粒子对胃癌淋巴结的诊疗一体化研究。

国家自然科学基金面上项目(项目编号:81371516):基于磁性荧光多功能探针USPIO- Cy5.5双模态成像精确清扫胃癌淋巴结研究

论文、成果、著作等

发表SCI论文65篇Liu S, Shi H, Ji C, Guan W, Chen L, Sun Y, Tang L, Guan Y, Li W, Ge Y, He J, Liu S, Zhou Z.CT textural analysis of gastric cancer: correlations with immunohistochemical biomarkers.Sci Rep. 2018 Aug 7;8(1):11844. IF:4.122

Meng J, Liu S, Zhu L, Zhu L, Wang H, Xie L, Guan Y, He J, Yang X, Zhou Z. Texture Analysis as Imaging Biomarker for recurrence in advanced cervical cancer treated with CCRT.Sci Rep. 2018 Jul 30;8(1):11399. IF:4.122

Shi H, Yan R, Wu L, Sun Y, Liu S, Zhou Z, He J, Ye D.Tumor-targeting CuS nanoparticles for multimodal imaging and guided photothermal therapy of lymph node metastasis.Acta Biomater. 2018 May;72:256-265. IF: 6.383

Zheng H, Ren W, Pan X, Zhang Q, Liu B, Liu S, He J, Zhou Z. Role of intravoxel incoherent motion MRI in early assessment of the response of esophageal squamous cell carcinoma to chemoradiotherapy: A pilot study.J Magn Reson Imaging. 2018 Jan 3.doi: 10.1002/jmri.25934.IF:3.612

Liu S, Zheng H, Zhang Y, Chen L, Guan W, Guan Y, Ge Y, He J, Zhou Z. Whole-volume apparent diffusion coefficient-based entropy parameters for assessment of gastric cancer aggressiveness.J Magn Reson Imaging. 2018 Jan;47(1):168-175. IF:3.612

Huo D, Liu S, Zhang C, He J, Zhou Z, Zhang H, Hu Y. Hypoxia-Targeting, Tumor Microenvironment Responsive Nanocluster Bomb for Radical-Enhanced Radiotherapy.ACS Nano. 2017 Oct 24;11(10):10159-10174.IF: 13.709

Liu S, Zhang Y, Chen L, Guan W, Guan Y, Ge Y, He J, Zhou Z. Whole-lesion apparent diffusion coefficient histogram analysis: significance in T and N staging of gastric cancers.BMC Cancer. 2017 Oct 2;17(1):665. IF:3.288

Zhu L, Wang H, Zhu L, Meng J, Xu Y, Liu B, Chen W, He J, Zhou Z, Yang X. Predictive and prognostic value of intravoxel incoherent motion (IVIM) MR imaging in patients with advanced cervical cancers undergoing concurrent chemo-radiotherapy.Sci Rep.2017 Sep 14;7(1):11635. IF:4.122

Ren S, Cheng X, Chen M, Liu C, Zhao P, Huang W, He J, Zhou Z, Miao L. Hypotoxic and Rapidly Metabolic PEG-PCL-C3-ICG Nanoparticles for Fluorescence-Guided Photothermal/Photodynamic Therapy against OSCC.ACS Appl Mater Interfaces. 2017 Sep 20;9(37):31509-31518. IF:8.097

Xu Y, Zhu L, Liu B, Ru T, Wang H, He J,Liu S, Yang X, Zhou Z,Liu T. Strain Elastography Imaging for Early Detection and Prediction of Tumor Response to Concurrent Chemo-Radiotherapy in Locally Advanced Cervical Cancer: Feasibility Study. BMC Cancer2017 Jun 19;17(1):427.IF:3.288

Hu Y, Cheng H, Zhao X, Wu J, Muhammad F, He J, Zhou L, Zhang C, Deng Y, Wang P,Zhou Z, Nie S, Wei H. Surface-Enhanced Raman Scattering Active Gold Nanoparticles with Enzyme Mimicking Activities for Measuring Glucose and Lactate in Living Tissues. ACS Nano.2017 Jun 27;11(6):5558-5566IF:13.709

Liu S, Liu S, Ji C, Zheng H, Pan X, Zhang Y, Guan W, Chen L, Guan Y, Li W, He J, Ge Y, Zhou Z. Application of CT texture analysis in predicting histopathological characteristics of gastric cancer. Eur Radiol.2017 Dec;27(12):4951-4959. IF: 4.027

Chu C, Zhang H, Zhou N, Dou X, Li M, Liu S, Zhu Y, Wang C, Chen W, Chan Q, Sun L, He J, Zhou Z.Diffusional kurtosis imaging of parotid glands in Sjögren's syndrome: Initial findings.J Magn Reson Imaging. 2017 Nov;46(5):1409-1417. IF:3.612

Chen B, Chen W, Chan Q, Zhou N, He J, Zhou Z. Functional MRI of human pancreas using BOLD contrast: Responses following glucose ingestion.J Magn Reson Imaging.2017 Sep;46(3):831-836. IF:3.612

Zheng M, Wang Y, Shi H, Hu Y, Feng L, Luo Z, Zhou M, He J,Zhou Z, Zhang Y, Ye D. Redox-Mediated Disassembly to Build Activatable Trimodal Probe for Molecular Imaging of Biothiols.ACS Nano.2016 Nov 22;10(11):10075-10085. IF: 13.709

Yu H, He J, Lu Q, Huo D, Yuan S, Zhou Z, Xu P, Hu Y. .Anti-Fas Antibody Conjugated Nanoparticles Enhancing the Antitumor Effect of Camptothecin by Activating the Fas-FasL Apoptotic Pathway.ACS Appl Mater Inter. 2016 Nov 9;8(44):29950-29959. IF:8.097

Zhou N, Chu C, Dou X, Li M, Liu S, Zhu L, Liu B, Guo T, Chen W, He J, Yan J, Zhou Z, Yang X, Liu T. Early evaluation of irradiated parotid glands with intravoxel incoherent motion MR imaging: correlation with dynamic contrast-enhanced MR imaging.BMC Cancer.2016 Nov 8;16(1):865. IF:3.288

Chu C, Zhou N, Zhang H, Dou X, Li M, Liu S, Zhu Y, Chen W, Chan Q, He J, Sun L, Zhou Z. Use of T1ρMR imaging in Sjögren's syndrome with normal appearing parotid glands: Initial findings.J Magn Reson Imaging.2017 Apr;45(4):1005-1012. IF:3.288

Zhang Y, Chen J, Liu S, Shi H, Guan W, Ji C, Guo T, Zheng H, Guan Y, Ge Y, He J,Zhou Z, Yang X, Liu T.Assessment of histological differentiation in gastric cancers using whole-volume histogram analysis of apparent diffusion coefficient maps.J Magn Reson Imaging.2017 Feb;45(2):440-449. IF:3.612

Zhu L, Zhu L, Shi H, Wang H, Yan J, Liu B, Chen W, He J,Zhou Z, Yang X, Liu T. Evaluating early response of cervical cancer under concurrent chemo-radiotherapy by intravoxel incoherent motion MR imaging.BMC Cancer.2016 Feb 10;16:79. IF:3.288

He J, Shi H,Zhou Z, Chen J, Guan W, Wang H, Yu H, Liu S,Zhou Z, Yang X, Liu T.Correlation between apparent diffusion coefficients and HER2 status in g astric cancers: pilot study.BMC Cancer. 2015 Oct 20;15:749. IF: 3.288

Yu H, Chen J, Liu S, Lu Q, He J,Zhou Z, Hu Y. Enzyme sensitive, surface engineered nanoparticles for enhanced delivery of camptothecin.J Control Release.2015 Oct 28;216:111-20. IF: 7.877

Liu S, Wang H, Guan W, Pan L,Zhou Z, Yu H, Liu T, Yang X, He J,Zhou Z.Preoperative apparent diffusion coefficient value of gastric cancer by diffusion-weighted imaging: Correlations with postoperative TNM staging.J Magn Reson Imaging. 2015 Sep;42(3):837-43. IF:3.612

Huo D, He J, Li H, Huang AJ, Zhao HY, Ding Y, Zhou ZY, Hu Y.X-ray CT guided fault-free photothermal ablation of metastatic lymph nodes with ultrafine HER-2 targeting W18O49 nanoparticles.Biomaterials.2014 Nov; 35(33): 9155-66. IF:8.806

Huo D, Ding J, Cui YX, Xia LY, Li H, He J, Zhou ZY, Wang HW, Hu Y. X-ray CT and pneumonia inhibition properties of gold-silver nanoparticles for targeting MRSA induced pneumonia.Biomaterials.2014 Aug;35(25):7032-41. IF:8.806

Huo D, He J, Li H, Yu H, Shi T, Feng Y,Zhou Z, Hu Y. Fabrication of Au@Ag core-shell NPs as enhanced CT contrast agents with broad antibacterial properties.Colloid Surface B. 2014 May 1;117:29-35. IF:3.997

专利、著作版权等

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