1984.7-1989.11 淮安市传染病防治院(四院) 住院医师 1989.11-2005.11 南京大学医学院附属鼓楼医院 主治医师、副教授 副主任/主任医师 2005.11-2011.12 南京大学医学院附属鼓楼医院 教授/主任医师 科教处长 2011.12- 南京大学医学院附属鼓楼医院 教授/主任医师 副院长

抗原负载的活化B细胞对HBV抗原特异性CTL的诱导作用

国家自然科学基金 2009-2011 33万

CD40配体活化的B细胞抗HBV的临床应用研究

卫生部科研项目资助课题 2006-2009 20万

以活化B细胞技术为基础的病毒性肝炎个体化综合抗病毒治疗新策略

江苏省医学创新团队与领军人才 2011-2015 80万

以活化B细胞技术为基础的慢性乙型病毒性肝炎治疗新策略

江苏省临床医学科技专项 2012-2015 50万

调节性B细胞在慢性乙型肝炎病毒感染中的负性调控作用

国家自然科学基金 2015-2016 30万

发表署名论文60余1.Yong Liu, Rui Huang, Yali Xiong, Qi Zhao, Guangmei Chen, Juan Xia, Chao Wu*. Soluble CD40 ligand-activated B cells from patients with chronic hepatitis B virus infection as antigen presenting cells to induce hepatitis B virus specific cytotoxic T lymphocytes. Biochemical and Biophysical Research Communications，2014 Jul 18;450(1):61-66 ;

2.Rui Huang, Chenchen Yang, Kangkang Wu, Shufeng Cao, Yong Liu, Ran Su, Yali Xiong, Aijun Huang, Chao Wu*. Red cell distribution width as a potential index to assess the severity of hepatitis B virus-related liver diseases Hepatology Research，2014 Apr 11，doi: 10.1111/hepr.12342

3.Rui Huang, Lu Zhang, Qin Gu, Yi-Hua Zhou, Yingying Hao, Kui Zhang, Yong Liu, Danjiang Dong, Shixia Wang, Zuhu Huang, Shan Lu, Chao Wu*. Profiles of Acute Cytokine and Antibody Responses in Patients Infected with Avian Influenza A H7N9. PLoS ONE 01/2014; 9(7):e101788.

4.Wu C, Huang R, Chen J, Gu Q, Zhu B, Wang J, Zhang K, Chen Q, Xiong C, Liu Y, Li J, Zhou YH, Ding Y*. Avian Influenza A(H7N9) Virus Screening in Patients with Fever and Flu-Like Symptoms in a Tertiary Hospital in an Area with Confirmed Cases. PLoS One. 2013; 8(12): e82613.

5.Wang Y, Zhang Y, Wang H, Zhou Z, Zhou Z, Gu Q, Wu C*, Zhu B. Sharing Insights and H7N9 Patient Clinical Data. Am J Respir Crit Care Med 2013; 188(1): 115-117.

6.Huang R, Hao Y, Fan Y, Yang C, Wu K, Cao S, Wu C*. Association Between Cytotoxic T-Lymphocyte-Associated Antigen 4 +49A/G Polymorphism and Persistent Hepatitis B Virus Infection in the Asian Population: Evidence from the Current Studies. Genet Test Mol Biomarkers 2013; 17(8): 601-606.

7.Rui Huang, Jun Zhang, Yong Liu, Yingying Hao, Chenchen Yang, Kangkang Wu, Shufeng Cao, Chao Wu*. Immunomodulatory effects of polysaccharopeptide in immunosuppressed mice induced by cyclophosphamide. Mol Med Rep 2013; 8: 669-675.

8.Rui Huang, Yingying Hao, Zhang Jun, Chao Wu*. Interferon-alpha plus adefovir combination therapy versus interferon-alpha monotherapy for chronic hepatitis B treatment: A meta-analysis. Hepatol Res. 2013 Oct;43(10):1040-51.

9.Wu C, Liu Y, Zhao Q,Chen G,Chen J,Yan X,Zhou YH,Huang Z. Soluble CD40 ligand-activated human peripheral B cells as surrogated antigen presenting cells: A preliminary approach for anti-HBV immunotherapy. Virol J 2010; 7: 370.

10.Zhou YH,Zhou J,Li L,Bi Y,Liu Y,Pan J,Wu C*. A novel hepatitis B virus mutant coexisting with wild type virus in a carrier with negative HBsAg yet positive HBeAg and anti-HBs. J Clin Virol 2009; 46: 363-366.

申请发明专利二项，批准专利一项