教育背景
2000.09 - 2004.07 中国药科大学,中药药剂学学士
2004.09 - 2007.07 中国科学院上海药物研究所,药物化学硕士
2007.08 - 2012.08 美国密苏里大学堪萨斯城分校,药剂学博士
工作经历
2012.09 - 2013.11 美国北卡罗来纳大学教堂山分校生物医学工程系,博士后
2013.12 - 2018.12 美国华盛顿大学生物工程系,博士后
2019.02 - 现在 武汉大学药学院,特聘研究员
项目课题经历
论文、成果、著作等
1. Wanyi Tai*. Current aspects of siRNA bioconjugate for in vitro and in vivo delivery. Molecules 2019, 24(12), 2211
2. Wanyi Tai*. Chemical Modulation of siRNA lipophilicity for efficient delivery. Journal of Controlled Release 2019, 307, 98- 107.
3. Wanyi Tai, Xiaohu Gao*. Silencing ribonucleoprotein: a biomimetic platform for targeted siRNA delivery. Advanced Functional Materials 2019, 29, 1902221
4. Wanyi Tai, Xiaohu Gao*. Synthetic polymer tag for intracellular delivery of siRNA. Advanced Biosystems 2018, 2. 1800075
5. Wanyi Tai, Junwei Li, Eva Corey, Xiaohu Gao*. A ribonucleoprotein octamer for targeted siRNA delivery. Nature Biomedical Engineering 2018, 2(5), 326-337
6. Wanyi Tai, Xiaohu Gao*. Noncovalent tagging of siRNA with steroids for transmembrane delivery. Biomaterials 2018, 178. 720-727.
7. Wanyi Tai, Xiaohu Gao*. Functional peptides for siRNA delivery Advanced Drug Delivery Reviews 2017, 110–111, 157–168.
8. Wanyi Tai, Ran Mo, Jin Di, Vinayak Subramanian, Xiao Gu, Zhen Gu*. Bio-inspired nanovesicles for glucose-responsive release of insulin. Biomacromolecules 2014, 15(10), 3495-3502.
9. Wanyi Tai#, Ran Mo#, Yue Lu, Tianyue Jiang, Zhen Gu*. Folding graft copolymer with pendant drug segment for co-delivery of anticancer drugs. Biomaterials 2014, 35(25), 7194-7203.
10. Wanyi Tai, Zhijin Chen, Ashutosh Barve, Zhonghua Peng, Kun Cheng*. A novel rapamycin-polymer conjugate based on a new poly(ethylene glycol) multiblock copolymer. Pharmaceutical Research 2014, 31(3), 706-719
11. Wanyi Tai, Zhijin Chen, Kun Cheng*. Expression profile and functional activity of peptide transporters in prostate cancer cells. Molecular Pharmaceutics 2013, 10(2), 477-487
12. Wanyi Tai, Ravi S. Shukla, Bin Qin, Benyi Li, Kun Cheng*. Development of a peptide-drug conjugate for prostate cancer therapy. Molecular Pharmaceutics 2011, 8(3), 901-912
13. Wan-Yi Tai#, Run-Tao Zhang#, Yi-Ming Ma, Min Gu, Gang Liu, Jia Li, Fa-Jun Nan*. Design, synthesis, and biological evaluation of ring‐opened bengamide analogues. ChemMedChem 2011, 6(9), 1555-1558.
14. Wanyi Tai, Rubi Mahato, Kun Cheng*. The role of HER2 in cancer therapy and targeted drug delivery. Journal of Controlled Release 2010, 146(3), 264-275
15. Wanyi Tai, Bin Qin, Kun Cheng*. Inhibition of breast cancer cell growth and invasiveness by dual silencing of HER-2 and VEGF. Molecular Pharmaceutics 2010, 7(2), 543-5561. Wanyi Tai, Zhen Gu*. Chapter 16 “Methods of folding a graft copolymer with dual anticancer drug and related applications” In Peter Grunwald edits “Biocatalysis & Nanotechnology” (2017), Pan Stanford Publishing Pte. Ltd.
2.Wanyi Tai, Kun Cheng*. Chapter 17 “Advanced drug delivery in cancer therapy” In Mitra AK, Lee C. Cheng K. edits “Advanced drug delivery” (2013), Wiley-Blackwell, John Wiley & Sons, Inc.
16. Gang Liu#, Yi-Ming Ma#, Wan-Yi Tai#, Chuan-Ming Xie, Yu-Lin Li, Jia Li and Fa-Jun Nan*. 2008, Design, synthesis, and biological evaluation of caprolactam-modified bengamide analogues. ChemMedChem 2008, 3(1), 74–78.
[12] 胡兵,汤俊 主编. “十二五” 全国高等学校教材,药物检测技术. 北京:中国协和医科大学出版社, 2014.11.
[13] 汤俊(编著者). 基础与临床中药毒理学(香港大学冯奕斌主编). 香港:商务印书馆, 2009, 11.
专利、著作版权等
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