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刘永梅

领域:生物产业 学校:武汉大学职称:副教授

天然活性产物挖掘及天然产物和药物的分子毒理学...

具体了解该专家信息,请致电:027-87555799 邮箱 haizhi@uipplus.com

教育背景

2001-2006:中国科学院水生生物研究所硕/博士

工作经历

2011-2012:美国Arizona State University 访问学者 2007-2009:中国科学院大连化学物理研究所/大连医诺生物有限公司 博士后 2006-至今:武汉大学 讲师/副教授

项目课题经历

主持或参与国家973子课题、中国博士后科学基金面上项目、国家863课题、国家自然科学基金面上项目等10余项,承担企业横向合作课题多项

论文、成果、著作等

近年来在Carbohydrate Polymers, Ecotoxicology and Environmental Safety, Journal of Ethnopharmacology,等杂志上发表论文20余篇1. Yongmei Liu, Wei Chen, Dunhai Li,Zebo Huang,Yinwu Shen,Yongding Liu*, Cyanobacteria-/cyanotoxin-contaminations and eutrophication status before Wuxi Drinking Water Crisis in Lake Taihu, China, Journal of Environmental Sciences, 2011, 23(4):575-581。

2. Liang Peng#,Yongmei Liu#, Wei Chen,Liming Liu,M Kent,Lirong Song*,Health risks associated with consumption of microcystin-contaminated fish and shellfish in three Chinese lakes: Significance for freshwater aquacultures. Ecotoxicology and Environmental Safety,2010, 73(1):1804-1811.

3. Haifeng Li, Juan Xu, Yongmei Liu*, Sshibin Ai, Fen Qin, Zhangwei Li, Hanrui Zhang, Zebo Huang*, Antioxidant and moisture-retention activities of the polysaccharide from Nostoc commune, Carbohydrate Polymers, 2011, 83(1):1821-1827.

4. Qing Zhu, Chaolin Liao*, Pengcheng Wang, Wei Guo, Mingjun He, Yongmei Liu*, Zebo Huang,Ethanolic extract and water-soluble polysaccharide from Chaenomeles speciosa fruit modulate lipopolysaccharide-induced nitric oxide production in RAW264.7 macrophage cells,Journal of Ethnopharmacology, 2012,144(4):441-447。

5. Shucai Liang, Yongmei Liu, Ting Fu, Fan Yang, Xiaohui Chen, Guoping Yan, A water-soluble and biocompatible polymeric nanolabel based onnaphthalimide grafted poly(acrylic acid) for the two-photonfluorescence imaging of living cells and C. elegans, Colloids and Surfaces B: Biointerfaces 2016, 148:293-298.

6. Lan Chen#, Ju Zhang#, Jie Xu, Lu Wan, Kaixuan Teng, Jin Xiang, Rui Zhang,

Zebo Huang, Yongmei Liu, Wenhua Li, Xin Liu*, rBmaTX14 Increases the Life Span and Promotes the Locomotion of Caenorhabditis elegans. PLoS ONE 11(9):e0161847. doi:10.1371/journal.pone.0161847.

7. Jing Chen, Ju Zhang, Yanxia Xiang, Limin Xiang, Yongmei Liu Xiangjiu He,Xiaoju Zhou,Xin Liu*, Zebo Huang*, Extract of Tsai Tai (Brassica chinensis): Enhanced Antioxidant Activity and Anti-aging Effects both in vitro and in Caenorhabditis elegans,Food & Function,2016, (7): 943-952.

8. Shibin Ai*,Tao Jia,Weilun Ai,Jianli Duan,Yongmei Liu,Jing Chen,Xin Liu,Fang Yang,Yuan Tian,Zebo Huang*, Targeted delivery of doxorubicin through conjugation with EGF receptor–binding peptide overcomes drug resistance in human colon cancer cells,British Journal of Pharmacology, 2013, 168(2):1719-1735。

9. Haifeng Li, Zhangwei Li,Siqin Xiong, Hanrui Zhang, Na Li, Shuanghui Zhou,Yongmei Liu,Zebo Huang*, Pilot-scale isolation of bioactive extracellular polymericsubstances from cell-free media of mass microalgal cultures using tangential-flow ultrafiltration,Process Biochemistry, 2011, 46(2):1104-1109。

10. HF Li, J Xu, YM Liu*, SB Ai, F Qin, ZW Li, HR Zhang, ZB Huang*. Antioxidant and moisture-retention activities of the polysaccharide from Nostoc commune. 2011. Carbohydrate Polymers, 83:1821-1827.

11. Huiling Li, Wei Chen,Yongmei Liu*, A high-Docosahexaenoic Acid Production Strain ofSchizochytrium sp. through Mutagenesis,2015 Global Conference on Biological Engineering and Biomedical,2015.1.19-2015.1.21。

12. ZM Xie, YX Wang, YD Liu, YM Liu. Ultraviolet-B exposure induces photo-oxidative damage and subsequent repair strategies in a desert cyanobacterium Microcoleus vaginatus Gom. 2009. European Journal of Soil Biology 45:377-382.

13. YM Liu, W Chen, DH Li, YW Shen, GB Li, YD Liu*. First report of aphantoxins in China—waterblooms of toxigenic Aphanizomenon flos-aquae in Lake Dianchi. 2006. Ecotoxicology and Environmental Safety, 65:84-92.

14. YM Liu, W Chen, DH Li, YW Shen, YD Liu, LR Song. Analysis of Paralytic Shellfish Toxins in Aphanizomenon DC-1 from Lake Dianchi, China. 2006. Environ Toxicol 21: 289-295.

15. 李慧玲, 刘永梅* , 诱变选育高产DHA裂殖壶菌突变株。食品科技,2015,40(9):12-16。

16. 肖凌云,李海峰,李姣,刘永梅,胡明华,马方励,基于高效液相色谱特征指纹图谱的黄芪-枸杞复合多糖的质量控制。中国医院药学杂志,2014:21,1795-1799。

专利、著作版权等

获国家授权发明专利7项1. 刘永梅,陈伟,陈晶,高永智,张秀梅。一种褐藻黄素的提取和纯化方法,专利号:ZL201410688099.9。授权公告日:2016.1.20。

2. 陈伟,曹腾腾,李康,徐瑶,刘永梅,曹磊,李西清。一种厚壁微藻天然虾青素的提取和含量测定方法。专利号:ZL201310618298.8.授权公告日:2016.1.13。

3. 陈伟,曹腾腾,李康,刘永梅,李西清,王志臻,潘倩倩。一种生物质材料油脂的提取方法及其应用。专利号:ZL201310638357.8. 授权公告日:2015.12.30.

4. 黄泽波、张晗蕊、潘妮、刘永梅、邹盛珑、李海峰,黄芪多糖作为制备治疗神经退行性疾病药物的应用。申请号:201010184836.3;申请公布号:CN 101829140 A;申请公布日:2010.09.15。

5. 黄泽波、刘永梅、李章伟、李海峰、李娜、周双辉,一种微藻胞外多糖的膜分离方法。专利号:ZL 201010184670.5;授权公告号:CN 101838342 B;授权公告日:2012.06.27。

6. 黄泽波、许娟、刘永梅、李海峰、刘永平、李章伟,念珠藻多糖在营养保湿型化妆品中的应用。专利号:ZL 200910063907.1;授权公告号:CN 101647759 B;授权公告日:2011.09.07。

7. 刘永定,刘永梅,陈伟,沈银武,李敦海,刘辉宇。一种束丝藻毒素的提取方法。专利号:ZL200410012865.6. 授权公告日:2006.08.30。
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