首页 > 专家库
陈子林

领域:生物产业 学校:武汉大学职称:教授

药物分析学...

具体了解该专家信息,请致电:027-87555799 邮箱 haizhi@uipplus.com

教育背景

江西大学化学系 理学学士(1984)

武汉大学化学系 理学硕士 (1991)

日本东京都立大学应用化学系 工学博士(2000)

工作经历

历任江西工业大学助教(1984-1988)、中德联合研究院讲师(1991-1996)、东京都立大学日本学术振兴会(JSPS)特别研究员(2000-2002)、日本NTT先端技术综合研究所博士后研究员(2002-2004)、美国圣母大学(University of Notre Dame)研究助理教授(2004-2007),

项目课题经历

1. 国家自然科学基金面上项目:基于毛细管电泳/电色谱-质谱联用技术的药物分析新方法(Grant No 81872828, 2019-2022)

2. 国家自然科学基金面上项目:新型固相微萃取及毛细管电色谱柱技术及其在药物分析中应用(Grant No. 81573384, 2016-2019)

3. 传感器国家重点实验室开放课题:甲基化DNA纳米传感器的研制与应用(2018.11-2020.10)

已结题项目

1. 国家自然科学基金面上项目:基于雌激素受体及芳香化酶靶向识别分析新方法及其在抗乳腺癌药物分析中应用(Grant No. 21375101, 2014-2017)

2. 国家自然科学基金重大研究计划集成项目:痕量植物激素实时原位及多组分同时检测创新方法研究(Grant No. 9141730002, 2015.01-2015.12)

3. 国家自然科学基金重大研究计划重点项目:茉莉酸类植物激素高效分离与高灵敏度检测及其在水稻颖花开放机理研究中应用(Grant No. 90817103, 2009-2012)

4. 国家自然科学基金面上项目: 二酰胺类手性硅胶整体柱技术及杂环类手性药物分离分析新方法研究(Grant No. 30973672, 2010-2012)

5. 国家自然科学基金国际(地区)合作与交流项目:2010中日韩分析化学研讨会(Grant No. 21010302029, 2010.10-2010.11)

6. 国家自然科学基金面上项目:新型毛细管电色谱-电喷雾离子化-质谱联用技术及其在生物与药物分析中的应用研究(Grant No, 20775055, 2008-2010)

7. 湖北省自然科学基金重点项目:新型固相微萃取-色谱-质谱联用技术及其在肿瘤诊断标志物筛选中 应用(Grant No. 2014CFA077, 2014-2016)

8. 传感技术联合国家重点实验室开放课题:一氧化氮纳米生物电化学传感器研究(Grant No. SKT1406, 2014.12-2017.12)

9. 湖北省自然科学基金“基于生物传感识别中药有效成分筛选分析新方法”(Grant No. 2011CDB475, 2011-2012)

10. 武汉市科技局应用基础研究计划项目:抗乳腺癌药物筛选与分析新技术(Grant No. 20140601001010057, 2014-2015)

11. 教育部博士点博导基金(Grant No. 20110141110024, 2012-2014)

12. 教育部留学回国人员启动基金(No. 教外司留[2008]890)

13. 中央高校专项研究基金 (Grant Nos: 306275547, 306275866, 2010-2011)

14. 武汉大学“珞珈学者特聘教授”启动基金(Grant Nos: 306276216, 306271159)

论文、成果、著作等

2019

1. Ling X, Chen Z. Immobilization of zeolitic imidazolate frameworks with assist of electrodeposited zinc oxide layer and application in online solid-phase microextraction of Sudan dyes[J]. Talanta, 2019, 192: 142-146.

2. Cheng M, Wang R, Zhang B, Mao Z, Chen Z. Rapid proteolytic digestion and peptide separation using monolithic enzyme microreactor coupled with capillary electrophoresis[J]. Journal of Pharmaceutical and Biomedical Analysis, 2019, 165: 129-134.

3. Chen Y, Wang R, Chen Z. Sensitive determination of psoralen and isopsoralen in Fructus Psoraleae by online solid phase microextraction with porphyrin-based porous organic polymers modified on capillary[J]. Analytical Methods, 2019 in pres.

4. Haiyan Yu, Patrick Chaimbault, Igor Clarot, Zilin Chen, Pierre Leroy , Labeling nitrogen species with the stable isotope 15N for their measurement T by separative methods coupled with mass spectrometry: A review, Talanta, 191(2019)491-503



2018

1. Rong Wang, Wenqing Li, Zilin Chen*, Solid phase microextraction with poly (deep eutectic solvent) monolithic column online coupled to HPLC for determination of non-steroidal anti-inflammatory drugs, Anal. Chim. Acta, 1018 (2018) 111-118.

2. Chenlu Wang, Wei Zhou, Xiaoyan Liao, Xuemei Wang, Zilin Chen*, Covalent immobilization of metal organic frameworks onto chemical resistant poly(ether ether ketone) jacket for stir bar extraction, Anal. Chim. Acta, 1025 (2018) 124-133.

3. Xiaoyan Liao, Fangli Hu, Zilin Chen*, Identification and Quantitation of the Bioactive Components in Osmanthus fragrans Fruits by HPLC-ESI-MS/MS, J. Agric. Food Chem., 66 (2018) 359-367.

4. Pingxiu Tang, Zilin Chen*, Capillary Electrochromatography Using Knitting Aromatic Polymers as the Stationary Phase for the Separation of Small Biomolecules and Drugs, Talanta, 178 (2018) 650-655.

5. Xuemei Wang, Wei Zhou, Chenlu Wang, Zilin Chen*, In situ immobilization of layered double hydroxides onto cotton fiber for solid phase extraction of fluoroquinolone drugs, Talanta, 186 (2018) 545-553.

6. Xu Ling, Zilin Chen*, Boronate affinity solid phase extraction of cis-diol compounds by one-step electrochemically synthesized selective polymer sorbent, Anal. Bioanal. Chem., 410 (2018) 501-508.

7. Wei Zhou, Chenlu Wang, Xuemei Wang, Zilin Chen*, Etched poly(ether ether ketone) jacket stir bar with detachable dumbbell-shaped structure for stir bar sorptive extraction, J. Chromatogr. A, 1553 (2018) 43-50.2016



1. X. Ling, W. Zhang, Z. Chen*, Electrochemically modified carbon fiber bundles as selective sorbent for online solid-phase microextraction of sulfonamides, Microchimica Acta , 183(2016)813-820.

2. Tao Bao, Pingxiu Tang, Deying Kong, Zhenkun Mao, and Zilin Chen*, Polydopamine-supported immobilization of covalent-organic framework-5 in capillary as stationary phase for electrochromatographic separation, J. Choromatogr. A, 1445(2016)140-148.

3. Tao Bao, Pingxiu Tang, Zhenkun Mao, Zilin Chen *An immobilized carboxyl containing metal-organic framework-5 stationary phase for open-tubular capillary electrochromatography, Talanta, 154(2016)360-366.

4. P. Tang, T. Bao, Z. Chen*, Novel Zn-based MOFs stationary phase with large pores for capillary electrochromatography, Electrophoresis, 37(2016)2081-2089.

5. Q. Xiang, Y. Hashi, Z. Chen*, Simultaneous detection of eight active components in Radix Tinosporae by ultra-high performance liquid chromatography coupled with electrospray tandem mass spectrometry, J.Sep. Sci. 39(2016)2036-2042.

6. L. Wang, W. Gong, F.. Wang*, Z. Yu, Z. Chen*, Efficient Bienzyme Nanocomposite Film for Chiral Recognition of L-tryptophan, L-phenylalanine and L-tyrosine, Anal. Methods, 8(2016)3481-3487.

7. L. Wang, F. Yu, F. Wang*, Z. Chen*, Electrochemical detection of DNA methylation using a glassy carbon electrode modified with a composite made from carbon nanotubes and β-cyclodextrin, Journal of Solid State Electrochemistry, J. Solid State Electrochem. 20(2016)1263-1270.

8. J. Han, J. Zhang, H. Zhao, Y. Li, Z. Chen*, Simultaneous determination of doxorubicin and its dipeptide prodrug in mice plasma by HPLC with fluorescence detection, J. Pharm. Anal. 6(2016)199-202.

9. . F. Wang*, W. Gong, L. Wang, Z. Chen*, Selective recognition of D-tryptophan from d/l-tryptophan mixtures in the presence of Cu(II) by electropolymerized L-lysine film, Anal. Biochem. 492(2016)30-33.

10. Z. Zhang, M. A. Mwadini, Z. Chen*, A polytetrafluoroethylene-jacketed stirrer modified with graphene oxide and polydopamine for efficient extraction of polycyclic aromatic hydrocarbons, J. Sep. Sci. 39(2016)4011-4018.

11. Jing Han, Zilin Chen, *Cathepsin B inhibitor screening in traditional Chinese medicines by electrophoretically mediated microanalysis, Anal. Methods, 8(2016)8528.

12. Su, C., Liu, C., Chen, J.Y., Chen, Z.L., and He, Z.K*. Simultaneous determination of zeatin and systemin by coupling graphene oxide-protected aptamers with catalytic recycling of DNase I. Sensors & Actuators 230(2016)442-448.





2015



1. T. Bao, J. Zhang, W. Zhang, Z. Chen*, Growth of metal-organic framework HKUST-1 in capillary using liquid-phase epitaxy for open-tubular capillary electrochromatography and capillary liquid chromatography, J.Chromatogr. A, 2015,1381,239-246.

2. J. Zhang, W. Zhang, T. Bao, Z. Chen*, Polydopamine-based immobilization of zeolitic imidazolate framework-8 for in-tube solid-phase microextraction, J.Chromatogr. A, 2015, 1388, 9-16.

3. W. Ma, P. Gao, J. Fan, Y. Hashi*, Z. Chen*, Determination of breath gas composition of lung cancer patients using gas chromatography/mass spectrometry with monolithic material sorptive extraction, Biomedical Chromatography, 2015, 29, 981-965.

4. Z. Zhang, W. Zhang, Z. Chen*, Jacket-free stir bar sorptive extraction with bio-inspired polydopamine-functionalized immobilization of cross-linked polymer on stainless steel wire, J. Chromatogr.A, 2015, 1407,1-10.

5. J. Meng, W.Zhang, T. Bao, Z. Chen*, Novel molecularly imprinted magnetic nanoparticles for selective extraction of protoberberine alkaloids in herbs and rat plasma, J. Sep. Sci. 2015, 38, 2117-2125.

6. L. Tang, W. Zhang, H. Zhao, Z. Chen*, Tyrosinase inhibitor screening in traditional Chinese medicines by electrophoretically mediated microanalysis, J. Sep. Sci. 2015, 38, 2887-2892.

7. F. Wang*, W. Gong, L. Wang, Z. Chen*, Enhanced amperometric response of a glucose oxidase and horseradish peroxidase based bienzyme glucose biosensor modified with a film of polymerized Toluidine Blue containing reduced graphene oxide, Microchimica Acta, 2015, 182, 1949-1956.

8. P. Jang, R. Huang, Z. Chen*, Thiol-based non-injection synthesis of near-infrared Ag2S/ZnS core/shell quantum dots, RSC Advance,2015, 5, 56789-56793.

9. Y. Wu, W. Zhang, Y. Chen, Z. Chen*, Electroosmotic pump-supported molecularly imprinted monolithic column for capillary chromatographic separation of nitrophenol isomers, Electrophoresis, 2015, 36,2881-2887.

10. F. Wang*, F. Yan, Y. Long, L. Wang, Z. Chen*, Interaction with deoxyribonucleic acid and determination of orientin in lophatherum gracile brongn by LC with amperometric detection, Electrochimica Acta, 2015 178, 829-837, .

11. X. Liu, W. Zhang, Z. Chen*, Preparation of a novel molecularly imprinted polymer for highly selective extraction of baicalin, J. Sep. Sci. 38(2015)4233-4239.

12. W. Zhang, Y. Li, Z. Chen*, Selective and sensitive determination of protoberberines by capillary electrophoresis coupled with molecularly imprinted microextraction, J. Sep. Sci. 2015, 38, 3969-3975.

13. Liu, C., Mao, G.B., Su, C., Ji, X.H., Chen, Z.L., and He, Z.K.* Aptamer-functionalized CdTe:Zn2+ quantum dots for the detection of tomato systemin. Anal. Methods 7 (2015) 7748-7752.
2014



1. W. Zhang, Z. Zhang, J. Zhang, J. Meng, T.Bao, Z. Chen*, Covalent immobilization of graphene onto stainless steel wire for jacket-free stir bar sorptive extraction, J. Chromatogr. A, 1351(2014)12-20

2. H. Zhao, Z. Chen*, Screening of neuraminidase inhibitors from traditional Chinese medicines by integrating capillary electrophoresis with immobilized enzyme microreactor, J. Chromatogr. A, 1340(2014)139-145

3. J. Zhang, W. Zhang, T. Bao, Z. Chen*, Enhancement of capillary electrochromatographic separation performance by conductive polymer in a layer-by-layer fabricated graphene stationary phase, J. Chromatogr. A,1339(2014)192-199.

4. W. Zhang, Z. Zhang, J. Meng, W. Zou, Z. Chen*, Adsorptive behavior and solid-phase microextraction of bare stainless steel sample loop in high performance liquid chromatography, J. Chromatogr. A, 1365(2014)19-28.

5. J. Zhang, W. Zhang, T. Bao, Z. Chen*, Mussel-inspired polydopamine-assisted hydroxyapatite as stationary phase for capillary electrochromatography, Analyst, 139(2014)242-250.

6. H. Zhao, Z. Chen*, Screening of neuraminidase inhibitors from traditional Chinese medicines by transverse diffusion mediated capillary electrophoresis, Biomicrofluidics, 8 (2014) 052003.



7. L. Ren, H. Zhao, Z. Chen*, Study on pharmacokinetic and tissue distribution of lycorine in mice plasma and tissues by liquid chromatography–mass spectrometry, Talanta, 119(2014)401-406

8. Y. Chen, Q. Xiang, Z. Chen*, Simultaneous and highly sensitive quantification of five bioactive components in Fructus Psoraleae and in rat plasma by HPLC with fluorescent detection, Anal. Methods, 2014, 6 (1), 269 - 275

9. J. Chen, J. Zhang, W. Zhang, Z. Chen*, Sensitive determination of potential biomarker sarcosine for prostate cancer by liquid chromatography-mass spectrometry with DCC derivatization, J. Sep. Sci. 37(2014)14-19.

10. W. Zhang†, W. Zhou†, Z. Chen*, Graphene/polydopamine-modified polytetrafluoroethylene micro-tube for sensitive determination of three active components in Fructus Psoraleae by online solid-phase microextraction-high performance liquid chromatography, J. Sep. Sci. 37(2014) 3110-3116. (†co-first author)

11. Y. Long, W. Zhang, F. Wang, Z. Chen*,Simultaneous determination of three curcuminoids in Curcuma longa L. by high performance liquid chromatography coupled with electrochemical detection, J. Pharm. Anal. 4(2014)325-330

12. 13. Q. Xiang, Y. Chen, Z. Chen*, Sensitive and simultaneous determination of active components in Lycoris radiata by high-performance liquid chromatography with fluorescence detection, Anal. Methods, 6(2014)8979-8985.





2013



1. W. Zhang, J. Zhang, T. Bao, W. Zhou, J. Meng, Z. Chen*, Universal multilayer assemblies of graphene in chemically resistant micro-tubes for microextraction, Anal. Chem. 85(2013)6845-6854.

2. L. Wang, P. Hu, X. Deng, F. Wang, Z. Chen*, Fabrication of Electrochemical NO sensor Based on Nanostructured Film and Its Application in Drug Screening, Biosensors & Bioelectronics, 50(2013)57-61.

3. W. Ma, S. Fu, Y. Hashi, Z. Chen*, Determination of chiral jasmonates in flowers by GC-MS after monolithic material sorptive extraction, J.Agric & Food Chem. 61(2013)6288-6292.

4. H. Zhao, Z. Chen*, Screening of aromatase inhibitors from traditional Chinese medicines by electrophoretically mediated microanalysis in partially filled capillary, J. Sep. Sci. 36(2013)2691-2697.

5. W. Zhang, Z. Chen*, Mussel inspired polydopamine functionalized poly(ether ether ketone) tube for online solid-phase microextraction-high performance liquid chromatography and its application in analysis of protoberberine alkaloids in rat plasma, J. Chromatogr. A, 1278(2013)29-36.

6. W. Zhang, J. Du, C. Su, L. Zhu, Z. Chen*, Development of β-cyclodextrin- modified silica and polyporous polymer particles for solid-phase extraction of methyl jasmonate in aqueous and plant samples, Anal. Lett. 46(2013) 900-911.

7. F. Wang, X. Sun, Y. Chen, S. Xie, Z. Chen*,Non-enzymatic Glucose Sensor Based on Copper Nanoparticles Modified Microelectrode, Nanosci. and Nanotech. Lett, 5(2013)624-629.

8. J. Liu, J. Zhang, Z. Chen*, Determination of bavachinin enantiomers in Fructus Psoraleae and rat plasma by liquid chromatography using permethylated-β-CD as a chiral selector, J. Pharm. Anal. 5(2013) 349-353.

9. X. Mou, W. Zhang, Z. Chen*,Highly selective extraction of baicalin in natural herbs and medicinal preparations by molecularly imprinted polymer, J. Applied Polymer Sci. 130(2013)1873-1878.

10. Y. Rang, W. Zhang, Z. Chen*, Determination of kynurenine and tryptophan in human plasma by stacking-micellar electrokinetic chromatography, Anal.Lett. 46(2013)2503-2513.

11. H. Zhao, Z. Chen*, An HPLC-ESI-MS method for Analysis of loureirin A and B in dragon’s blood and Application in Pharmacokinetics and tissue distribution in rats, Fitoterapia, 86(2013)149-158.

12. Y. Zhang, Z. Chen*, Nonaqueous Capillary Electrophoresis Electrospray Ionization-Ion Trap-Mass Spectrometric Analysis of Amaryllidaceae Alkaloids, J. Sep.Sci. 36(2013)1078-1084.

13. Y. Chen, Z. Chen*, Simultaneous separation of jasmonic acid conjugates with amino acids by micellar electrokinetic chromatography, J. Sep. Sci., 36(2013)892-897.

14. J. Zhang, Z. Chen*, Determination of matrine and oxymatrine in Sophora Flavescens by non-aqueous capillary electrophoresis-electrospray ionization-ion trap-mass spectrometry, Anal. Lett. 46(2013)651-662.

15. Q. Chen, W. Zhang, Y. Zhang, J. Chen, Z. Chen*, Identification and quantification of active alkaloids in Catharanthus roseus by liquid chromatography-ion trap mass spectrometry, Food Chem. 139(2013)845-852.

16. Y. Chen, Z. Chen*, Fluorescein-core piperazine as a fluorescent labeling reagent for highly sensitive determination of jasmonic acid by high-performance liquid chromatography, Anal. Method, 5(2013)1733-1738.

17. Q. Chen, J. Zhang, W. Zhang, Z. Chen*, Analysis of active alkaloids in family Menispermaceae by nonaqueous capillary electrophoresis- ion trap mass spectrometry, J. Sep. Sci. 36(2013)341-349.

18. S. Xie, F. Wang, Z. Chen*, Determination of Endogenous Jasmonic Acid in Plant Samples by Liquid Chromatography-Electrochemical Detection Based on Derivatization with Dopamine, Analyst, 128(2013)1226-1231.

19. W. Zhang, Z. Chen*, A polymer monolith microextraction coupled with HPLC for determination of jasmonates in wintersweet flowers, Anal. Lett. 46(2013)74-86.

20. W. Zhang, Z. Chen*, Preparation of micropipette tip-based molecularly imprinted monolith for selective micro-solid phase extraction of berberine in plasma and urine samples, Talanta, 103(2013)103-109.



2012



1. J. Zhang, T. Bao, Z. Chen*, Determination of polycyclic aromatic hydrocarbons on polymeric SMA-EGDMA mononlith column by capillary electrochromatography, Anal. Method. 4(2012)4140-4145.

2. J. Chen, Q. Chen, Z. Chen*Enhancing Sensitivity of Liquid Chromatographic/Ion-trap Mass Spectrometric Determination of Jasmonic Acid by Derivatization with N, N' –Dicyclohexylcarbodiimide, Analyst,137( 2012)5436-5440.

3. Y. Wu, W. Zhang, Z. Chen*, A poly (4-vinylpridine-co-ethylene glycol dimethacrylate) monolithic concentrator for in-line concentration-capillary electrophoresis analysis of phenols in water samples, Electrophoresis, 33(2012)2911-2919.

4. X. Dang, C. Dang, Z. Chen, S. Wang, S. Hu, Electrochemical characteristics of cis-jasmone in acid media at multi-wall carbon nanotube-Nafion composite film modified electrode and its analytical application, Electrochem. Acta, 81(2012)239-245.

5. Y. Zhang, Z. Chen*, Separation of isomeric bavachin and isobavachalcone in the Fructus Psoraleae by capillary electrophoresis-electrospray-mass spectrometry, J. Sep. Sci. 35(2012)1644-1650.

6. L. Liu, Z. Chen*, Analysis of four alkaloids of Coptis chinensis in rat plasma by high performance liquid chromatography with electrochemical detection, Anal. Chim. Acta, 737(2012)99-104.

7. S. Fu, J. Fan, Y. Hashi*, Z. Chen*, Determination of polycyclic aromatic hydrocarbons in water samples using online microextraction by packed sorbent coupled with gas chromatography-mass spectrometry, Talanta, 94(2012)152-157.

8. Y. Zhang, L. Huang, Q. Chen, Z. Chen*, A silica monolithic column chemically bonded L-pipecolic acid as chiral stationary phase for enantiomeric separations of dansyl amino acids by capillary electrochromatography-mass spectrometry, Chromatographia, 75(2012)289-296.

9. Q.Chen, Y. Li, Z. Chen*, Separation, identification and quantification of active constituents in Fructus Psoraleae by high-performance liquid chromatography with UV, ion trap mass spectrometry and electrochemical detection, J. Pharma. Anal. 2(2012)143-151.

10. L. Liu, S. Li, Z. Chen*, Simultaneous determination of tetrandrine and fangchinoline in herbal medicine Stephania tetrandra S. Moore by liquid chromatography with electrochemical detection, J. Pharma.& Biomed. Anal. 61(2012)251-255.



2011



1. F. Yan, F. Wang, Z. Chen*, label-free aptamer-based biofunctional electtrochemical biosensor for thrombin and adenosine, Sensors and Actuators B Chemical. 160(2011)1380-1385.

2. Q. Chen, N. Li, W. Zhang, J. Chen and Z. Chen*, Simultaneous determination of vinblastine and its monomeric precursors vindoline and catharanthine in Catharanthus roseus by capillary electrophoresis-mass spectrometry, J. Sep. Sci. 34(2011)2885-2892

3. Q. Chen, Y. Zhang, W. Zhang, Z. Chen*, Identification and quantification of oleanolic acid and ursolic acid in Chinese herbs by liquid chromatography-ion trap mass spectrometry, Biomed. Chromatogr. 25(2011)1381-1388.

4. Q. Chen, S. Luo, Y. Zhang, Z. Chen*, Development of a liquid chromatography-mass spectrometry method for the determination of ursolic acid in rat plasma and tissue: Application to the pharmacokinetic and tissue distribution study, Anal. Bioanal Chem. 399(2011)2877-2884.

5. Y. Li, F. Wang, Z. Chen*, Determination of bavachin and isobavachalcone in Fructus Psoraleae by high-performance liquid chromatography with electrochemical detection, J. Sep. Sci. 34(2011) 514-519.

6. F. Wang, X. Chen, Z. Chen*, Eletrodeposited nickel oxide on a film of carbon nanotubes

For monitoring nitric oxide release from rat kidney and drug samples,Microchim. Acta, 173(2011)65-72.

7. L. Liu, Y. Chen, Y. Zhang, F. Wang and Z. Chen*, Determination of tryptophan and kynurenine in human plasma by liquid chromatography-electrochemical detection with multi-wall carbon nanotube-modified glassy carbon electrode, Biomed. Chromato., 25(2011)938-942.

8. F. Wang, X. Deng, W. Wang, Z. Chen*, Nitric oxide measurement in biological and pharmaceutical samples by a novel electrochemical sensor, J. Solid State Electrochem., 15(2011)829-836.

9. L. Yang, Z. Chen*, Direct evaluation of ligand-receptor interaction by a novel imaging model based on fluorescent silica nanoparticle as ligand probe and molecular imprinting polymer as artificial receptor, Anal. Lett. 44(2011)687-697

10. Tian Gan, Chengguo Hu, Zilin Chen, Shengshui Hu, A disposable electrochemical sensor for the determination of indole–3–acetic acid based on poly(safranine T)–reduced graphene oxide nanocomposite, Talanta,85(2011)310-316

11. Tian Gan, Chengguo Hu, Zilin Chen, Shengshui Hu, Novel electrocatalytic system for the oxidation of methyl jasmonate based on layer-by-layer assembling of montmorillonite and phosphotungstic acid nanohybrid on graphite electrode, Electrochimica Acta, 56(2011)4512-4517

12. X. Dang, C. Hu, Z. Chen,S. Hu, A novel electrochemical method for determination of cis-jasmone based on enhancement effect of cetyltrimethylammonium bromide, J. Electroanal. Chem., 657(2011)39-45



2010



1. W. Zhang, Y. Wu, Y. Chen, H. Jiang, Z. Chen*, Simultaneous separation of four metal ions by capillary electrophoresis using bis (2-pyridylmethyl) (8-pyridylmethyloxy-quinoline-2-methyl)-amine as chelating agent, Chromatographia, 72(2010)1201-1205.

2. T. Gan, C. Hu, Z. Chen, S. Hu*, Direct electrochemical determination of methyl jasmonate in wheat spikelet at a nano-montmorillonite film modified electrode by derivative square wavevoltammetry, J. Agric Food Chem.,58(2010)8942-8947.

3. T. Gan, C. Hu, Z. Chen, S. Hu*, Fabrication and application of a novel plant hormone sensor for the determination of methyl jasmonate based on self-assembling of phosphotungstic acid-graphene oxide nanohybrid on graphite electrode, Sensor and Actuators B: Chemical, 151(2010)8-14.

4. Y. Liao, F. Wang, Z. Chen*, Electrochemical behavior and the determination of methyl jasmonates, Chinese Sci. Bull, 55(21)(2010)2225-2230

5. X. Deng, F. Wang Z. Chen*, A novel electrochemical sensor based on nano-structured film electrode for monitoring nitric oxide in living tissues, Talanta, 82(2010)1218-1224.

6. F. Wang, Y. Liao, Y. Ren, Z. Chen*, A novel method for D-arabinitol determination based on a nano-structured sensing film by one-step electrodeposition, Microchim. Acta, 17(2010)9-15, 2009.

7. Q. Chen, S. Weißig, S. Luo, Z. Chen*, Simultaneous determination of five anti-epilepsy drugs in human plasma using liquid chromatography-mass spectrometry, Sci China B Chem, 53(2010)2373-2378.

8.

2009





1. L. Liu, Z. Chen*, “Separation of small molecular peptides with the same amino acid composition but different sequences by high performance liquid chromatography-electrospray ionization-mass spectrometry”, Sci China B Chem, 52 (12) (2009) 2264-2268.

2. Y. Weng, Z. Chen*, F. Wang, L. Xue H. Jiang "High sensitive determination of zinc with novel water-soluble small molecular fluorescent sensor" Anal. Chim. Acta, 647(2009) 215-218.

3. D. Feng, F. Wang, Z. Chen*, “Electrochemical glucose sensor based on one step construction of gold nanoparticle-chitosan composite film”, Sensors & Actuators: B. Chemical, 138 (2009) 539-544

4. Y. Wu, J. Xie, F. Wang, Z. Chen*, ‘Separation of small molecular peptides with same amino acid composition and different sequences by capillary electrophoresis’, J. Sep. Sci. 32(2009)437-440.



2008



1. X. Chen, F. Wang, Z. Chen*, “An electropolymerized Nile Blue sensing film-based nitrite sensor and application in food analysis”, Anal. Chim.Acta, 623(2008)213-220.

2. Y. Wu, J. Xue, F. Wang, Z. Chen*, ‘Electrokinetic separation of peptides and proteins using polyvinylamine-coated capillary with UV and ESI-MS detections’, J. Sep. Sci. 31(2008) 814-823.



2007 and before 2007



1. Z. Chen, B. Boggess, H. C. Chang, ‘Open-tubular capillary electrochromatography-mass spectrometry with sheathless nanoflow electrospray ionization for analysis of amino acids and peptides’, J. Mass Spec. 42(2007)244-253.

2. Z. Chen, F.-C. Hsu, D. Battigelli, H. C. Chang, ‘Capture and release of virus using amino-funcitonalized silica particles, Anal. Chim. Acta, 569(2006)76-82.

3. P. Wang, Z. Chen, and H. C. Chang, ‘An integrated micropump and electrospray emitter based on porous silica monliths’, Electrophoresis, 27(2006)3964-3970.

4. P. Wang, Z. Chen, and H. C. Chang, ‘A new electroosmotic pump based on silica monoliths’, Sensors and Actuators B, 113 (2006)500-509.

5. C. Hu, Z. Chen, A. Shen, X. Shen, J. Li, S.S.Hu, ‘Water-soluble single-walled carbon nanotubes via noncovalent functionalization by rigid, planar and conjugated diazo dye’ Carbon, 44(2006)428-434.

6. Z. Chen, P. Wang, H. C. Chang, ‘An electroosmotic micro-pump based on monolithic silica for micro flow analyses and electrosprays’, Anal.& Bioanal. Chem., 382(2005)817-824.

7. Z. Chen, H. C. Chang, T. Hobo, ‘Application of monolithic silica matrix in microfluidic analysis’(invited), Bunseki Kagaku (Japanese Anal. Chem.), 54(2005)583.

8. Z. Chen, K. Hayashi, Y. Iwasaki, R. Kurita, O. Niwa, K. Sunagawa, ‘On-line monolithic enzyme reactor fabricated by sol-gel process for elimination of ascorbic acid while monitoring dopamine’, Electroanalysis. 17 (2005)231-238.

9. Z. Chen, K. Uchiyama, T. Hobo, ‘Chiral resolution of dansyl amino acids by ligand exchange capillary electrophoresis using Cu(II)-L-Prolinamides as chiral selectors’ Anal. Chim. Acta, 523(1)(2004)1-7.

10. Z. Chen, T. Fuyumuro, K. Watabe, T. Hobo, ‘Influence of spacers and organic modifiers on chromatographic behaviors on chiral diamide stationary phase with N-(3,5-Dimethylbenzoyl)-D-phenylglycine’ Anal. Chim. Acta, 518(1-2)(2004) 181-189.

11. Z. Chen, T. Nishiyama, K. Uchiyama, T. Hobo, ‘Electrochromatographic enantioseparation using chiral ligand exchange monolithic sol-gel column’ Anal. Chim. Acta, 501(1)(2004) 17-23.

12. T. You, O. Niwa, Z. Chen, K. Hayashi, M. Tomita, S. Hirono, ‘A novel amperometric detector formed of highly dispersed Ni nano-particles embedded in a graphite-like carbon film electrode for sugar determination’, Anal. Chem. 75 (2003) 5191-5196.

13. H. Ozawa, Z. Chen, K. Kawata, T. Nakagama, K. Uchiyama, T. Hobo, ‘Capillary electrochromatographic behaviors of dansyl amino acid enantiomers on cyclodextrin-immolilized monolithic silica column’, Bunseki Kagaku, (Japanese Anal. Chem.) 52(12)(2003)1105-1112.

14. T. Nishiyama, Z. Chen, T. Nakagama, K. Uchiyama, T. Hobo, ‘Separation of dansyl amino acid enantiomers by ligand exchange capillary electrochromatography ushing L-lysinamide-modified monolithic silica column’, Bunseki Kagaku (Japanese Anal. Chem.), 52(2003)1005-1010.

15. Z. Chen, M. Niidzma, K. Uchiyama and T. Hobo, ‘Comparisons of enantioseparations using Cu(II) complexes with L-amino acid amides as chiral selectors or chiral stationary phases by CE, CEC and micro-LC’, J. Chromatogr. A, 990 (2003) 75-82.

16. Z. Chen, H. Ozawa, K. Uchiyama and T. Hobo, ‘Cyclodextrin-modified monolithic silica column for resolving of dansyl amino acid enantiomers and positional isomers by capillary electrochromatography’, Electrophoresis, 24(15)(2003)2550-2558.

17. Z. Chen, T. Fuyumuro, T. Nakagama, K. Uchiyama and T. Hobo, ‘New diamide-type chiral stationary phase for chiral separations by normal and reverse phases HPLC’, J. Liquid Chromatogr. & Related Tech., 26(13)(2003)2103-2117.

18. Z. Chen, T. Nakayama, T. Nakagama, K. Uchiyama and T. Hobo, ‘Thermodynamic Approaches to Intermolecular Interaction and Retention Behaviors in Liquid Chromatography’, J. Liquid Chromatogr. & Relative Tech., 26(17)(2003)2809-2838.

19. Z. Chen, K. Uchiyama and T. Hobo, ‘Chemically modified chiral monolithic silica column for the enantioseparation by m-HPLC’, J. Chromatogr. A, 942(2002) 83-91.

20. Z. Chen, M. Niidzma, T. Nakagama, K. Uchiyama and T. Hobo, ‘Enantioseparations of dansyl amino acids unsing Cu(II) complexes with L-amino acylamides as chiral selectors in electrolytes by capillary electrophoresis’, J. Sep. Sci, 25(2002)1197-1201.

21. Z. Chen and T. Hobo, ‘Chemically L-phenylalaninamide-modified monolithic silica column prepared by sol-gel process for enantioseparation of dansyl amino acids by ligand exchange-capillary electrochromatography’, Anal. Chem., 73 (2001) 3348-3357.

22. Z. Chen and T. Hobo, ‘Chemically L-prolinamide-modified monolithic silica column for enantiomeric separation of hydroxy acids and dansyl amino acids by capillary electrochromatography and m-HPLC’, Electrophoresis, 22 (2001) 3339-3346.

23. Z. Chen, K. Uchiyama and T. Hobo, ‘Interaction between 18-crown-6-tetracarboxylic acid and positional substituents of enantiomers and simultaneous separation of positional enantiomers of methyl-DL-tryptophans by capillary electrophoresis’, Electrophoresis, 22 (2001) 2136-2142.

24. Z. Chen, K. Yamada, M. Niitsuma, K. Uchiyama and T. Hobo, ‘Separation selectivity in micellar electrokinetic chromatography using different anionic surfactants as pseudo-stationary phases’, Chromatographia, 54 (2001) 629-633.

25. Z. Chen, K. Uchiyama and T. Hobo, ‘18-crown-6-tetracarboxylic acid as a chiral additive for the simultaneous separation of o-, m- and p-enantiomers of phenylalanine family by capillary electrophoresis’, Enantiomer, 6 (2001) 19-25.

26. Z. Chen, ‘Ligand exchange-micellar electrokinetic chromatography and its applications’ (Digest of doctoral dissertation in Japanese), Bunseki Kagaku (Japanese Anal. Chem.), 49 (2000) 713-714.

27. Z. Chen, K. Uchiyama and T. Hobo, ‘Estimation of formation constants of ternary Cu(II) complexes with mixed amino acid enantiomers based on ligand exchange by capillary electrophoresis’, Anal. Sci., 16(8) (2000) 837-841.

28. Z. Chen, K. Uchiyama and T. Hobo, ‘Separation of hydroxy acid enantiomers by ligand exchange-micellar electrokinetic chroamtography’ (in Japanese), Bunseki Kagaku (Japanese Anal. Chem.), 49(10) (2000) 759-764.

29. Z. Chen, J. Lin, K. Uchiyama and T. Hobo, ‘Determination of critical micelle concentration of anionic surfactants by ligand exchange micellar electrokinetic chromatography’, Anal. Chem. Acta, 403 (2000) 173-178.

30. Z. Chen, J. Lin, K. Uchiyama and T. Hobo, ‘Reversal behavior of the enantiomers migration order and the stereo-selectivity of Cu(II) complex with amino acid enantiomers in ligand-exchange micellar electrokinetic chromatography’, Anal. Sci., 16(2) (2000) 131-137.

31. Z. Chen, J. Lin, K. Uchiyama and T. Hobo, ‘Simultaneous separation of sixteen positional and optical isomers of the tryptophan family by ligand-exchange micellar electrokinetic chromatography’, Chromatographia, 49 (1999) 436-443.

32. Z. Chen, J. Lin, K. Uchiyama and T. Hobo, ‘Separation behavior of amino acid enantiomers in ligand-exchange micellar electrokinetic chromatography’, J. Microcol. Sep., 11 (1999) 534-540.

33. Z. Chen, J. Lin, K. Uchiyama and T. Hobo, ‘Simultaneous separation of o-, m-, p-fluoro-DL-phenylalanine and o-, m-, p-DL-tyrosine by ligand exchange micellar electrokinetic capillary chromatography’, J. Chromatogr. A, 813 (1998) 369-378.

34. Z. Chen, G. Xu, K. Specht, R. Yang and S. She, ‘Determination of taurine in biological samples by reversed-phase liquid chromatography with precolumn derivatization with dinitrofluorobenzene’, Anal. Chim. Acta, 296 (1994) 249-253.

35. S. S. Hu, Z. Chen and T. Zhang, ‘Adsorptive stripping voltammetry of testosterone propionate in pharmaceutical preparations’, Fresenius’ J. Anal. Chem., 346 (10-11) (1993) 1008-10.


8. Deying Kong, Zilin Chen*, Open-tubular capillary electrochromatography using carboxylatopillar[5]arene as stationary phase, Electrophoresis, 39 (2018) 363-369.

9. Xuemei Wang, Wei Zhou, Chenlu Wang, Zilin Chen*, Cotton fiber-supported layered double hydroxides for the highly efficient adsorption of anionic organic pollutants in water, New Journal of Chemistry, 42 (2018) 9463-9471.

10. Rong Wang, Zilin Chen*, Boronate affinity monolithic column incorporated with graphene oxide for the in‐tube solid‐phase microextraction of glycoproteins. J. Sep. Sci., 41 (2018) 2767-2773.

11. Mengxia Cheng, Zilin Chen*, Recent advances in screening of enzyme inhibitor based on capillary electrophoresis. J. Pharmaceut. Anal., 8(2018)226-233.

12. Pingxiu Tang, Rong Wang, Zilin Chen*, In situ growth of Zr-based metal-organic framework UiO-66-NH2 for open-tubular capillary electrochromatography, Electrophoresis, 39(2018)2619-2625.

13. Wenqing Li, Rong Wang, Zilin Chen*, Metal-organic framework UiO-66-modified cotton for solid phase micro-extraction of non-steroidal anti-inflammatory drugs, J. Chromatogr. A, 1576(2018)19-25.

14. Rong Wang, Zhenkun Mao, Zilin Chen*, Monolithic column with polymeric deep eutectic solven

专利、著作版权等

声明:本站专家信息来源于各高校官网。