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熊朝梅

领域:生物产业 学校:华中科技大学职称:副教授

主要从事新型固相萃取材料的制备和微型化固相萃取装置的设计,并实现上述萃取材料和萃取装置在环境、食品以及生物样品中的痕量/超痕量药物的分析研究;中药/天然产物活性成分的分离与分析、体内药物分析、中药指纹图谱分析和药物质量评价等。...

具体了解该专家信息,请致电:027-87555799 邮箱 haizhi@uipplus.com

教育背景

1995.09 ~ 1999.07武汉大学化学系应用化学专业,获应用化学理学学士学位;

2002.09 ~ 2007.06武汉大学化学系硕博连读,获分析化学理学博士学位;

工作经历

2007.07 ~ 2009.06华中科技大学同济医学院药学院从事博士后研究; 2009.07 ~迄今 华中科技大学同济医学院药学院从事教学和科学研究; 2011.10~2012.10加拿大滑铁卢大学访问学者

项目课题经历

1) 2012.01-2014.12,主持国家自然科学基金一项;

(2) 2012.01-2014.12,主持教育部博士点新教师基金一项;

(3) 2013.01-20114.12,主持校基金一项。

论文、成果、著作等

[1] Wei, Han; Wu, Guanghua; Chen, Jinglou; Zhang, Xuenong;Xiong, Chaomei; Lei, Yongfang; Chen, Wei; Ruan, Jinlan, (2S)-5, 2', 5'-Trihydroxy-7-Methoxyflavanone, a Natural Product from Abacopteris penangiana, Presents Neuroprotective Effects In Vitro and In Vivo, Neurochemical Research,AUG 2013, 38(8), 1686-1694

[2] Yang, Aixia; Wang, Xiaoxian;Xiong, Chaomei; Chen, Jing; Ruan, Jinlan, Quality control of tuirejieduling granules using high-performance liquid chromatography fingerprint method and simultaneous determination of four main active ingredients, Pharmacognosy Magazine, APR-JUN 2013, 9(34): 162-166

[3] Chen, Jing;Xiong, Chao-Mei; Song, Shan-Shan; Han, Pan; Ruan, Jin-Lan,Fraction of Macroporous Resin from Smilax china L. Inhibits Testosterone Propionate-Induced Prostatic Hyperplasia in Castrated Rats, Journal of Medicinal Food,JUL 2012, 15(7): 646-650

[4] Yuan, Qianying; Cai, Shaoxin; Zhang, Xuenong; Liu, Ziwei; Li, Zhaoming; Luo, Xuelai;Xiong, Chaomei; Wang, Jianping; Hu, Junbo; Ruan, Jinlan. A new protoapigenone analog RY10-4 induces apoptosis and suppresses invasion through the PI3K/Akt pathway in human breast cancer.Cancer Letters (New York, NY, United States) (2012), 324(2), 210-220.

[5] Wei, Anhua; Zhou, Daonian; Ruan, Jinlan; Cai, Yaling;Xiong, Chaomei; Wu, Guanghua. Anti-tumor and anti-angiogenic effects of Macrothelypteris viridifrons and its constituents by HPLC-DAD/MS analysis. Journal of Ethnopharmacology (2012), 139(2), 373-380.

[6] Liu, Huibin; Jiang, Chunyang;Xiong, Chaomei; Ruan, Jinlan. DEDC, a new flavonoid induces apoptosis via a ROS-dependent mechanism in human neuroblastoma SH-SY5Y cells. Toxicology In Vitro, (2012), 26(1), 16-23.

[7] Wu Guanghua; Cai Yaling; Wei Han; Wei Anhua;Xiong Chaomei; Fu Wei; Ruan Jinlan. Nephroprotective activity of Macrothelypteris oligophlebia rhizomes ethanol extract. Pharmaceutical biology (2012), 50(6), 773-7.

[8] Ruan, Jinlan; Yuan, Qianying;Xiong, Chaomei; Liu, Ziwei.Preparation of 2-(1-hydroxy-4-oxo-2,5-cyclohexadien-1-yl)-4H-pyran-4-one as antitumor agent.Faming Zhuanli Shenqing (2012),CN 102731456 A 20121017.

[9] Chen, Jinglou; Lei, Yongfang; Wu, Guanghua; Zhang, Yonghui; Fu, Wei;Xiong, Chaomei; Ruan, Jinlan. Renoprotective potential of Macrothelypteris torresiana via ameliorating oxidative stress and proinflammatory cytokines. Journal of Ethnopharmacology (2012), 139(1), 207-213.

[10]Liu, Ziwei; Yuan, Qianying; Zhang, Xuenong;Xiong, Chaomei; Xue, Pingping; Ruan, Jinlan. RY10-4, a novel anti-tumor compound, exhibited its anti-angiogenesis activity by down-regulation of the HIF-1α and inhibition phosphorylation of AKT and mTOR. Cancer Chemotherapy and Pharmacology (2012), 69(6), 1633-1640.

[11]HB Liu, YL Xiao,CM Xiong, AH Wei, JL Ruan. Apoptosis induced by a new flavonoid in human hepatoma HepG2 cells involves reactive oxygen species-mediated mitochondrial dysfunction and MAPK activation,European Journal of Pharmacology, 2011, 654(3): 209–216.

[12]YF Lei, W Fu, JL Chen,CM Xiong, GH Wu, H Wei, JLRuan.Neuroprotective effects of Abacopterin E fromAbacopteris penangianaagainst oxidative stress-induced neurotoxicity,Journal of Ethnopharmacology, 2011, 134(2): 275-280.

[13]YF Lei, JL Chen, YL Cai,CM Xiong, JL Ruan. Hypolipidemic potential ofLepidogrammitis drymoglossoidesin high-fat diet fed mice,International Journal of Cardiology, 2011, 147(2), 323–325.

[14]JL Chen, YF Lei, YJ Liu,CM Xiong, W Fu,JL Ruan, Extract ofCyclosorus acuminatusattenuates diabetic nephropathy in miceviamodifying peroxisome proliferators activated receptor signalling pathway, Food Chemistry, 2011, 128(3): 659-666.

[15]Y Tang,CM Xiong, DN Zhou, AH Wei, W Fu, YL Cai, JL Ruan. A new flavonoid fromMacrothelypteris torresiana. Chemistry of Natural Compounds,2010, 46(2): 209–211.

[16]XH Huang, PC Xiong,CM Xiong, YL Cai, AH Wei, JP Wang, XF Liang, JL Ruan.In vitro and in vivo antitumor activity ofMacrothelypteris torresianaand its acute/subacute oral toxicity,Phytomedicine, 2010, 17(12): 930–934.

[17]W Fu, YF Lei, JL Chen,CM Xiong, DN Zhou, GH Wu, J Chen, YL Cai, JL Ruan. Parathelypteriside attenuates cognition deficits in D-galactose treated miceby increasing antioxidant capacity and improving long-term potentiation,Neurobiology of Learning and Memory,2010, 94(3): 414–421.

[18]CM Xiong, YC Qin, B Hu.On-line separation/preconcentration of V(IV)/V(V) in environmental water samples with CTAB-modified alkyl silica microcolumn and their determination by inductively coupled plasma-optical emission spectrometry,Journal of Hazardous Materials, 2010, 178(1-3): 164–170.

[19]CM Xiong, B Hu. Headspace trapping of the hydrides on a Pd (II)-coated graphite adsorptive bar as a microextraction method for ETV-ICP-MS determination of Se, Te and Bi in seawater and human hair samples,Talanta, 2010, 81(1-2): 578–585.

[20]DN Zhou, JL Ruan, YL Cai,CM Xiong, W Fu, AH Wei. Antioxidant and hepatoprotective activity of ethanol extractArachniodes exilis(Hance) Ching,Journal of Ethnopharmacology, 2010, 129(2): 232–237.

[21]黄晓华,蔡亚玲,熊朝梅,汪建平,阮金兰.普通针毛蕨黄酮类成分原芹菜素的血浆蛋白结合率的测定,中国医院药学杂志, 2010, 30(9): 725–728.

[22]CM Xiong, JL Ruan, YL Cai, Y Tang. Extraction and determination of some psychotropic drugs in urine samples using dispersive liquid-liquid microextraction followed by high-performance liquid chromatography,Journal of Pharmaceutical and Biomedical Analysis, 2009, 49(2): 572–578.

[23]CM Xiong, M He, B Hu. Microcolumn separation/preconcentration combined with fluorinating electrothermal vaporization inductively coupled plasma mass spectrometry for determination of trace refractory elements in seawater, soil and sediment,Geostandards and Geoanalytical Research, 2009, 33(3): 385–396.

[24]CM Xiong, JL Ruan, Y Tang, YL Cai, W Fang, Y Zhu, DN Zhou. Chromatographic fingerprint analysis ofMacrothelypteris torresianaand simultaneous determination of several main constituents by LC,Chromatographia, 2009, 70: 117–124.

[25]熊朝梅,蔡亚玲,阮金兰,方伟,汤莹,祝勇,周道年,彭可垄.梯度反相高效液相色谱法测定普通针毛蕨地下部分Protoapigenone含量,医药导报, 2009, 28(8): 1077–1078.

[26]CM Xiong, M He, B Hu. On-line separation and preconcentration of inorganic arsenic and selenium species in natural water samples with CTAB-modified alkyl silica microcolumn and determination by inductively coupled plasma-optical emission spectrometry,Talanta, 2008, 76(4): 772–779.

[27]CM Xiong, B Hu, ZC Jiang. Synergic solvent extraction of rare earth elements using mixed ligand complexes of hexafluoroacetylacetone and tri-n-butylphosphate and their determination in environmental waters by low temperature ETV-ICP-MS,Atomic Spectroscopy, 2008, 29(1): 6–15.

[28]CM Xiong,B Hu. Online YPA4resin microcolumn separation/ preconcentration coupled with inductively coupled plasma optical emission spectrometry (ICP-OES) for the speciation analysis of mercury in seafood,Journal of Agricultural and Food Chemistry, 2007, 55(25): 10129–10134.

[29]CM Xiong,ZC Jiang, B Hu. Speciation of dissolved Fe(II) and Fe(III) in environmental water samples by micro-column packed withN-benzoyl-N-phenylhydroxylamine loaded on microcrystalline naphthalene and determination by electrothermal vaporization inductively coupled plasma-optical emission spectrometry,Analytica Chimica Acta,2006, 559(1): 113–119.

[30]YW Wu, ZC Jiang, B Hu,CM Xiong, YJ Li. In-situ separation and determination of palladium from platinum based on different vaporization temperatures by electrothermal vaporization inductively coupled plasma optical emission spectrometry with YPA4resin acting both as adsorption material and chemical modifier,Microchimica Acta,2004, 148(3-4): 279–284.

专利、著作版权等

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