2001.9-2004.7: 华中科技大学同济医学院药学院，获得药理学博士学位。

1996.9-1999.7: 同济医科大学药学院，获药物化学专业硕士学位。

1985.9-1989.7: 中国药科大学中药系，获理学学士学位。

2014.11-今: 华中科技大学同济药学院教授，硕士、博士生导师，中药与天然药物学系主任。 2011.3-2014.11: 华中科技大学同济药学院教授，硕士、博士生导师，天然药物化学与中药学系副主任；天然药物化学课程群负责人。 2009.11-2011.2: 华中科技大学同济药学院教授，硕士、博士生导师。 2002.7-2009.10: 华中科技大学同济药学院副教授，硕士生导师。 1997.1-2002.6: 华中科技大学同济医学院药学院讲师。 1992.12-1997.12: 同济医科大学药学院助教。

2018.01-2021.12：国家自然科学基金《基于多靶点机制的三种五味子属植物及其内生真菌抗AD活性成分研究》/负责/项目编号31770380。

2016.01-2019.12：国家自然科学基金《三种核桃属植物PIN1靶向抗肿瘤萘醌类成分及作用机制》/负责/项目编号21572073。

2013.01-2016.12：国家自然科学基金《金山五味子治疗阿尔茨海默症活性成分及机制》/负责/课题编号31270394。

2011.1-2013.12：国家自然科学基金《换锦花抗AD活性成分及作用机制研究》/ 负责/课题编号81072547。

2009.1-2011.12：国家自然科学基金《野核桃青果皮抗肿瘤活性成分及作用机制研究》/负责/课题编号30873361。

2010.7-2013.6: 科技部国际合作项目《石蒜属植物中化学成分治疗阿尔茨海默症的临床前研究》/ 89万 / 负责。

2013.01-2015.12：武汉市科技攻关项目《野核桃中新型凋亡诱导剂YHT-2和YHT-3抗肿瘤成药性评价》/负责。

2010.1-2012.12：教育部留学回国人员启动基金《Aspergillus fischerianus次生代谢物生物合成研究》/教外司留(2008)890号 / 负责。

2009.9-2011.8：重大新药创制专项创新药物研究项目《来源于野核桃青果皮的抗肿瘤药物的研究与开发》/ 20万 /负责。

2009.1-2009.12：中韩合作课题《从传统中药中开发出天然药物或功能性食品的新原料》/ 3万 /负责。

* Ming Zhou, Jia Zhou, Junjun Liu, Jing-Jing Liang, Xiao-Gang Peng, Fang-Fang Duan, and Han-Li Ruan*. Parasubindoles A-G, Seven Eremophilanyl Indoles from the Whole Plant of Parasenecio albus. The Journal of Organic Chemistry, 2018, Just Accepted Manuscript, DOI: 10.1021/acs.joc.8b02089, Publication Date (Web): September 10, 2018

* Jian Song, Ming Zhou, Jia Zhou, Jing-Jing Liang, Xiao-Gang Peng, Junjun Liu, and Han-Li Ruan*. Schincalactones A and B, Two 5/5/6/11/3 Fused Schinortriterpenoids with a 13-Membered Carbon Ring System from Schisandra incarnate. Organic Letters, 2018, 20 (8), 2499-2502

* Ye Liu, Heng-Yi Yu, Hong-Zhe Xu, Jun-Jun Liu, Xiang-Gao Meng, Ming Zhou, and Han-Li Ruan*. Alkaloids with Immunosuppressive Activity from the Bark of Pausinystalia yohimbe. Journal of Natural Products, 2018, 81 (8), 1841–1849

* Jingjing Liang, Xiaogang Peng, Jia Zhou, Ming Zhou, Hanli Ruan* Diarylheptanoids from the Fresh Pericarps of Juglans sigillata, Chemistry of Natural Compounds, 2018, accepted

* Wenming Wu & Hanli Ruan* Triterpenoids and lignans from the stems of Schisandra glaucescens Natural Product Research, 2018 Mar 12:1-7

* Jingjing Liang, Xiaogang Peng, Jia Zhou, Ming Zhou & Hanli Ruan* Diarylheptanoids from the fresh pericarps of Juglans sigillata, Natural Product Research, 2017 Dec 28:1-7

* Jian Song, Ye Liu, Ming Zhou, Hui Cao, Xiao-Gang Peng, Jing-Jing Liang, Xiao-Ya Zhao, Ming Xiang, Han-Li Ruan*. Spiroschincarins A–E: Five Spirocyclic Nortriterpenoids from the Fruit of Schisandra incarnata. Organic Letters, 2017, 19 (5), 1196–1199

* Ye Liu, Heng-Yi Yu, Yan-Mei Wang, Tian Tian, Wen-Ming Wu, Ming Zhou, Xiang-Gao Meng, Han-Li Ruan*. Neuroprotective Lignans from the Fruits of Schisandra bicolor var. tuberculata. Journal of Natural Products, 2017, 80 (4), 1117–1124

* Ye Liu, Tian Tian, Heng-Yi Yu, Ming Zhou, Han-Li Ruan*. Nortriterpenoids from the stems and leaves of Schisandra viridis, Fitoterapia, 2017, 118: 38-41

* An Jin, Wen-Ming Wu, Han-Li Ruan*. Sesquiterpenoids and monoterpenoid coumarins from Parasenecio rubescens, Rsc Advances, 2017, 7(9), 5167–5176

* Ye Liu, Yan-Mei Wang, Wen-Ming Wu, Jian Song, Han-Li Ruan*. Triterpenoids and lignans from the fruit of Schisandra sphenanthera. Fitoterapia, 2017, 116:10–16

* Ming Zhou, Ye Liu, Jian Song, Xiao-Gang Peng, Qi Cheng, Hui Cao, Ming Xiang, and Han-Li Ruan*, Schincalide A, a Schinortriterpenoid with a Tricyclo[5.2.1.01,6]decane-Bridged System from the Stems and Leaves of Schisandra incarnate. Organic Letters, 2016, 18 (18), 4558–4561

* Wen-Ming Wu, Xu Chen, Ye Liu, Yan-Mei Wang, Tian Tian, Xiao-Ya Zhao, Juan Li, Han-Li Ruan*. Triterpenoids from the branch and leaf of Abies fargesii. Phytochemistry, 2016, 130, 301–312

* Heng-Yi Yu, Juan Li, Ye Liu, Wen-Ming Wu, Han-Li Ruan*. Triterpenoids from the fruit of Schisandra glaucescens. Fitoterapia, 2016, 113, 64–68.

* Wen-Ming Wu, Ye Liu, Xu Chen, An Jin, Ming Zhou, Tian Tian, Han-Li Ruan*, Diterpenoids from the branch and leaf of Abies fargesii, Fitoterapia, 2016, 110: 123-128.

* 毛瑞华,钟志宏,吴文明,刘叶,阮汉利*.鄂西大蓟茎叶化学成分研究[J].中草药, 2016,47(13): 2236-2240.

* Tian Tian, Ye Liu, Heng-Yi Yu, Yun-Yun Zhu, Xiao-Ya Zhao, Han-Li Ruan* Dibenzocyclooctadiene Lignans from the Fruits of Schisandra viridis, Chemistry of Natural Compounds, 2015, 51 (6):1046-1048

* An Jin, Wen-Ming Wu, Heng-Yi Yu, Ming Zhou, Ye Liu, Tian Tian, and Han-Li Ruan* Bisabolane-Type Sesquiterpenoids from the Whole Plant of Parasenecio rubescens, Journal of Natural Products, 2015, 78 (8): 2057–2066

* Yun-Yun Zhu, Xue Li, Heng-Yi Yu, Yu-Fang Xiong, Peng Zhang, Hui-Fang Pi, Han-Li Ruan* Alkaloids from the bulbs of Lycoris longituba and their neuroprotective and acetylcholinesterase inhibitory activities Archives of Pharmacal Research, 2015, 38 (5): 604-613

* Yuan Gan, Yang Zhang, Aiqian Li, Chengwu Song, Chang Chen, Yong Xu, Hanli Ruan*, Hongliang*. Jiang, A Novel Four-step Approach for Systematic Identification of Naphthoquinones in Juglans cathayensis Dode using Various Scan Functions of Liquid Chromatography-Tandem Mass Spectrometry along with Data Mining Strategies. Phytochemical Analysis, 2015, 26(6): 413–422

Zhenzhong Chen, Ling Tong, Yuanli Feng, Jizhou Wu, Xiaoya Zhao, Hanli Ruan, Huifang Pi, Peng Zhang, Ursane-type nortriterpenes with a five-membered A-ring from Rubus innominatus. Phytochemistry 2015, 116, 329-336.

* Heng-Yi Yu, Zu-Yu Chen, Bin Sun, Junjun Liu, Fan-Yu Meng, Ye Liu, Tian Tian, An Jin, and Han-Li Ruan*, Lignans from the Fruit of Schisandra glaucescens with Antioxidant and Neuroprotective Properties, Journal of Natural Products , 2014, 77 (6): 1311–1320

* An Jin, Xue Li, Yun-Yun Zhu, Heng-Yi Yu, Hui-Fang Pi, Peng Zhang, Han-Li Ruan* Four New Compounds from the Bulbs of Lycoris aurea with Neuroprotective Effects against CoCl2 and H2O2-induced SH-SY5Y Cell Injuries, Archives of Pharmacal Research 2014, 37: 315-323

* Wen-Ming Wu, Yun-Yun Zhu, Hao-ran Li, Heng-Yi Yu, Peng Zhang, Hui-Fang Pi, Han-Li Ruan* Two new alkaloids from the bulb of Lycoris sprengeri Journal of Asian Natural Products Research, 2014, 16(2): 192-199.

Ke Jiao, Huo-Yun Li, Peng Zhang, Hui-Fang Pi, Han-Li Ruan, Ji-Zhou Wu Two new ent-kaurane diterpenoids from the aerial parts of Isodon excisoides Chinese Chemical Letters 2014, 25(1): 131-133.

Ling Tong, Tu Chen, Zhenzhong Chen, Peng Zhang, Huifang Pi, Hanli Ruan, Jizhou. Wu, Anti-inflammatory activity of omphalocarpin isolated from Radix Toddaliae Asiaticae. Journal of Ethnopharmacology 2014, 155 (3), 1553-1560.

Juan Li, Hang Chang, Wenyu Zhao, Huifang Pi, Hanli Ruan, Peng. Zhang, New Alkaloids from Aconitum vaginatum. Helvetica Chimica Acta 2014, 97 (5), 689-693.

* Heng-Yi Yu, Xiao-Qiong Zhang, Xue-Li, Fan-Bo Zeng, Han-Li Ruan* 2-Methoxyjuglone Induces Apoptosis in HepG2 Human Hepatocellular Carcinoma Cells and Exhibits in Vivo Antitumor Activity in a H22 Mouse Hepatocellular Carcinoma Model, Journal of Natural Products 2013, 76(5): 889−895

* Juan Li, Jia-Xiang Sun, Heng-Yi Yu, Zu-Yu Chen, Xiao-Ya Zhao, Han-Li Ruan* Diarylheptanoids from the root bark of Juglans cathayensis, Chinese Chemical Letters 2013, 24: 521-523

* Xue Li, Heng-Yi Yu, Zhuo-Yi Wang, Hui-Fang Pi, Peng Zhang, Han-Li Ruan* Neuroprotective Compounds from the Bulbs of Lycoris radiate, Fitoterapia 2013, 88: 82-90.

Ke Jiao, Huo-Yun Li, Peng Zhang, Hui-Fang Pi, Han-Li Ruan, Ji-Zhou Wu Three new ursane-type triterpenoids from the aerial parts of Isodon excisoides Journal of Asian Natural Products Research 2013, 15(9): 962-968.

Kun Yang, Ling Tong, Chunxia Chen, Peng Zhang, Huifang Pi, Hanli Ruan, Jizhou. Wu, Therapeutic effects of extracts from Radix Toddaliae Asiaticae on collagen-induced arthritis in Balb/c mice. Journal of Ethnopharmacology 2013, 146 (1), 355-362.

* Heng-Yi Yu, Cui Hao, Fan-Yu Meng, Xue Li, Zu-Yu Chen, Xi Liang, Han-Li Ruan* Neuroprotective Lignans from the Stems of Schisandra glaucescens Planta Medica 2012, 78: 1962-1966

* Jia-Xiang Sun, Xiao-Ya Zhao, Xiao-Fang Fu, Heng-Yi Yu, Xue Li, Shu-Ming Li, Han-Li Ruan* Three new naphthalenyl glycosides from the root bark of Juglans cathayensis, Chemical and Pharmaceutical Bulletin 2012, 60: 785-789.

Kathrin Mundt, Beate Wollinsky, Han-Li Ruan, Tianjiao Zhu and Shu-Ming Li, Identification of the verruculogen prenyltransferase FtmPT3 by a combination of chemical, bioinformatic and biochemical approaches. Chembiochem 2012, Nov 26; 13(17): 2583-2592 (This paper was selected as issue cover)

* Fan-Yu Meng, Jia-Xiang Sun, Xue Li, Heng-Yi Yu, Shu-Ming Li, and Han-Li Ruan*. Schiglautone A, a New Tricyclic Triterpenoid with a Unique 6/7/9-Fused Skeleton from the Stems of Schisandra glaucescens. Organic Letters, 2011, 13 (6): 1502–1505

* Fan-Yu Meng, Jia-Xiang Sun, Xue Li, Hui-Fang Pi, Peng Zhang, Han-Li Ruan*. Triterpenoids from the Stems of Schisandra glaucescens. Helvetica Chimica Acta, 2011, 94(10):1778-1785

* Heng-Yi Yu, Xue Li, Fan-Yu Meng, Hui-Fang Pi, Peng Zhang, Han-Li Ruan* Naphthoquinones from the root barks of Juglans cathayensis Dode. Journal of Asian Natural Products Research, 2011, 13 (7): 581-587.

Li, Lujun; Zhang, Yue; Zhang, Peng; Pi, Huifang; Ruan, Hanli; Wu, Jizhou. Appraisal of anti-inflammatory and free radical scavenging activities of ethanol extract of Ilex ficoidea Hemsl and Ilex centrochinensis S.Y. Hu. Environmental Toxicology and Pharmacology 2011, 32(2), 122-127.

Zhang, Yue; Li, Lu-Jun; Zhang, Peng; Pi, Hui-Fang; Ruan, Han-Li; Wu, Ji-Zhou. Three New E-Secoursane Triterpenoid Saponins from the Leaves of Ilex dunniana. Helvetica Chimica Acta 2011, 94(12): 2207-2214.

Chen Chunxia, Zhang Peng, Pi Huifang, Ruan Hanli, Hu Zehua,Wu Jizhou. Extracts of Arisaema rhizomatum C.E.C. Fischer attenuate inflammatory response on collagen-induced arthritis in BALB/c mice. Journal of Ethnopharmacology. 2011, 133: 573-582

Li, Lu-Jun; Zhang, Yue; Zhang, Peng; Pi, Hui-Fang; Ruan, Han-Li; Wu, Ji-Zhou. Flavans from the leaf of Ilex centrochinensis. Journal of Asian Natural Products Research 2011, 13(4): 367-372.

Li, Lu-Jun; Zhang, Yue; Zhang, Peng; Pi, Hui-Fang; Ruan, Han-Li; Wu, Ji-Zhou. Two new 5,8-quinoflavans from the leaf of Ilex centrochinensis. Journal of Asian Natural Products Research 2011, 13(4): 341-345.

* 陈超，胡钰，孙家祥，皮慧芳，张鹏，阮汉利*. 野核桃叶化学成分研究. 中草药, 2011，42(11), 2177-2180

张悦, 李陆军, 张鹏, 皮慧芳, 阮汉利, 吴继洲.冬青属两种植物的抗炎作用及自由基清除能力研究. 华中科技大学学报(医学版), 2011, 40(1), 71-74.

* 张悦，阮汉利*，张勇慧，皮慧芳，吴继洲 鄂西大蓟根的化学成分的研究 天然产物研究与开发，2010, 22(1): 58-59

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